(5 nodes) XPG/Rad2 endonuclease network (Xiphophorus maculatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	gen1	Uncharacterized protein. (897 aa)
	ercc5	Excision repair cross-complementation group 5. (1097 aa)
	exo1	Exonuclease 1. (777 aa)
	fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
	LOC102220076	Zgc:110269. (347 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102220076	ercc5	ENSXMAP00000004359	ENSXMAP00000019246	Zgc:110269.	Excision repair cross-complementation group 5.	0.403
LOC102220076	exo1	ENSXMAP00000004359	ENSXMAP00000010534	Zgc:110269.	Exonuclease 1.	0.840
LOC102220076	fen1	ENSXMAP00000004359	ENSXMAP00000006136	Zgc:110269.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.905
ercc5	LOC102220076	ENSXMAP00000019246	ENSXMAP00000004359	Excision repair cross-complementation group 5.	Zgc:110269.	0.403
ercc5	exo1	ENSXMAP00000019246	ENSXMAP00000010534	Excision repair cross-complementation group 5.	Exonuclease 1.	0.422
ercc5	fen1	ENSXMAP00000019246	ENSXMAP00000006136	Excision repair cross-complementation group 5.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.403
exo1	LOC102220076	ENSXMAP00000010534	ENSXMAP00000004359	Exonuclease 1.	Zgc:110269.	0.840
exo1	ercc5	ENSXMAP00000010534	ENSXMAP00000019246	Exonuclease 1.	Excision repair cross-complementation group 5.	0.422
exo1	fen1	ENSXMAP00000010534	ENSXMAP00000006136	Exonuclease 1.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.840
exo1	gen1	ENSXMAP00000010534	ENSXMAP00000031938	Exonuclease 1.	Uncharacterized protein.	0.719
fen1	LOC102220076	ENSXMAP00000006136	ENSXMAP00000004359	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Zgc:110269.	0.905
fen1	ercc5	ENSXMAP00000006136	ENSXMAP00000019246	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Excision repair cross-complementation group 5.	0.403
fen1	exo1	ENSXMAP00000006136	ENSXMAP00000010534	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Exonuclease 1.	0.840
gen1	exo1	ENSXMAP00000031938	ENSXMAP00000010534	Uncharacterized protein.	Exonuclease 1.	0.719