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gfm1 gfm1 mvd mvd lonp1 lonp1 mlh1 mlh1 LOC102224127 LOC102224127 mlh3 mlh3 mrps5 mrps5 galk2 galk2 mrps9 mrps9 rps16 rps16 LOC102221193 LOC102221193 EFL1 EFL1 rps2 rps2 pms2 pms2 top2a top2a LOC102226546 LOC102226546 top2b top2b eftud2 eftud2 mvk mvk galk1 galk1 lonp2 lonp2 pms1 pms1 gfm2 gfm2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
gfm1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (748 aa)
mvdDiphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (403 aa)
lonp1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (990 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (754 aa)
LOC102224127Tr-type G domain-containing protein. (858 aa)
mlh3MutL homolog 3 (E. coli). (1151 aa)
mrps5Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (405 aa)
galk2Galactokinase 2. (458 aa)
mrps9Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (380 aa)
rps16Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
LOC102221193Eukaryotic translation elongation factor 2b. (884 aa)
EFL1Elongation factor like GTPase 1. (1105 aa)
rps2Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (279 aa)
pms2PMS1 homolog 2, mismatch repair system component. (826 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1536 aa)
LOC102226546Glucuronokinase with putative uridyl pyrophosphorylase. (495 aa)
top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1589 aa)
eftud2Elongation factor Tu GTP binding domain containing 2. (971 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
galk1Galactokinase 1. (393 aa)
lonp2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (841 aa)
pms1PMS1 homolog 1, mismatch repair system component. (860 aa)
gfm2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (765 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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