(52 nodes) Synthesis of PC network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102236050	Solute carrier family 44 member 2; Belongs to the CTL (choline transporter-like) family. (837 aa)
	LOC102219135	Uncharacterized protein; Belongs to the type-B carboxylesterase/lipase family. (1090 aa)
	chpt1	Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (382 aa)
	LPIN2	Lipin 2. (831 aa)
	chat	Choline O-acetyltransferase a; Belongs to the carnitine/choline acetyltransferase family. (676 aa)
	LOC102224728	Major facilitator superfamily domain containing 2B. (608 aa)
	ABHD1	Abhydrolase domain containing 1. (422 aa)
	LOC102230116	Choline kinase beta. (487 aa)
	lpin1	Si:ch73-21k16.1. (902 aa)
	LPCAT1	Lysophosphatidylcholine acyltransferase 1. (474 aa)
	abhd3	Abhydrolase domain containing 3. (412 aa)
	cept1	Choline/ethanolamine phosphotransferase 1b; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (423 aa)
	MFSD2A	Major facilitator superfamily domain containing 2aa. (520 aa)
	LOC102221217	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (390 aa)
	LOC102229928	Abhydrolase domain containing 15a. (499 aa)
	LOC102232864	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	stard10	StAR-related lipid transfer (START) domain containing 10. (262 aa)
	LOC102219566	Phosphatase, orphan 2. (244 aa)
	pctp	Phosphatidylcholine transfer protein. (212 aa)
	ABHD2	Abhydrolase domain containing 2b. (436 aa)
	slc44a5	Solute carrier family 44 member 5b; Belongs to the CTL (choline transporter-like) family. (713 aa)
	LOC102222257	START domain containing 14. (262 aa)
	LOC102224007	Lysophosphatidylcholine acyltransferase 1. (497 aa)
	LOC102217403	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (215 aa)
	LOC102234135	Solute carrier family 44 member 1b; Belongs to the CTL (choline transporter-like) family. (742 aa)
	LOC102218840	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family. (633 aa)
	LOC102237732	StAR-related lipid transfer (START) domain containing 15. (275 aa)
	LOC102217388	Uncharacterized protein; Belongs to the CTL (choline transporter-like) family. (654 aa)
	mfsd2a	Major facilitator superfamily domain containing 2ab. (515 aa)
	pemt	Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family. (238 aa)
	LOC102221099	Lipin 1. (960 aa)
	LOC102229890	Zgc:171501. (487 aa)
	LOC102221937	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (356 aa)
	LOC102237852	Zgc:123305. (985 aa)
	LOC102233739	Phosphate cytidylyltransferase 1, choline, alpha a. (380 aa)
	Phospho1	Phosphatase, orphan 1. (274 aa)
	M4AZL9_XIPMA	Uncharacterized protein. (281 aa)
	LOC102218083	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (543 aa)
	ENSXMAP00000020901	COesterase domain-containing protein. (83 aa)
	LOC102234606	Abhydrolase domain containing 2a. (431 aa)
	slc44a4	Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (718 aa)
	LOC102233830	Zgc:86598; Belongs to the protein kinase superfamily. (394 aa)
	LOC102223556	Phosphate cytidylyltransferase 1, choline, beta b. (356 aa)
	LOC102238080	Hydrolase_4 domain-containing protein. (548 aa)
	LOC102225161	Choline kinase alpha. (418 aa)
	CSNK2A2	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
	LOC102229902	Zgc:63569; Belongs to the CTL (choline transporter-like) family. (728 aa)
	ENSXMAP00000034487	COesterase domain-containing protein. (250 aa)
	pcyt1b	Phosphate cytidylyltransferase 1, choline, beta a. (361 aa)
	LOC102228807	Lipin 2. (949 aa)
	stard7	StAR-related lipid transfer (START) domain containing 7. (413 aa)
	LOC102216626	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (596 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSNK2A2	LOC102217403	ENSXMAP00000032258	ENSXMAP00000014181	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.982
CSNK2A2	LOC102221217	ENSXMAP00000032258	ENSXMAP00000007876	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.943
CSNK2A2	LOC102221937	ENSXMAP00000032258	ENSXMAP00000018470	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	0.900
CSNK2A2	LOC102232864	ENSXMAP00000032258	ENSXMAP00000010327	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.982
CSNK2A2	LOC102233830	ENSXMAP00000032258	ENSXMAP00000025584	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	Zgc:86598; Belongs to the protein kinase superfamily.	0.943
LOC102217403	CSNK2A2	ENSXMAP00000014181	ENSXMAP00000032258	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	0.982
LOC102217403	LOC102221217	ENSXMAP00000014181	ENSXMAP00000007876	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.982
LOC102217403	LOC102221937	ENSXMAP00000014181	ENSXMAP00000018470	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.	0.982
LOC102217403	LOC102232864	ENSXMAP00000014181	ENSXMAP00000010327	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.900
LOC102217403	LOC102233830	ENSXMAP00000014181	ENSXMAP00000025584	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Zgc:86598; Belongs to the protein kinase superfamily.	0.982
LOC102218840	LOC102225161	ENSXMAP00000014858	ENSXMAP00000031998	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Choline kinase alpha.	0.902
LOC102218840	LOC102230116	ENSXMAP00000014858	ENSXMAP00000004658	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Choline kinase beta.	0.901
LOC102218840	M4AZL9_XIPMA	ENSXMAP00000014858	ENSXMAP00000019914	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Uncharacterized protein.	0.900
LOC102218840	Phospho1	ENSXMAP00000014858	ENSXMAP00000019786	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Phosphatase, orphan 1.	0.902
LOC102218840	chat	ENSXMAP00000014858	ENSXMAP00000003019	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	Choline O-acetyltransferase a; Belongs to the carnitine/choline acetyltransferase family.	0.901
LOC102221099	LOC102225161	ENSXMAP00000017598	ENSXMAP00000031998	Lipin 1.	Choline kinase alpha.	0.452
LOC102221099	LOC102230116	ENSXMAP00000017598	ENSXMAP00000004658	Lipin 1.	Choline kinase beta.	0.452
LOC102221099	cept1	ENSXMAP00000017598	ENSXMAP00000006019	Lipin 1.	Choline/ethanolamine phosphotransferase 1b; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.722
LOC102221099	chpt1	ENSXMAP00000017598	ENSXMAP00000001484	Lipin 1.	Choline phosphotransferase 1; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.722
LOC102221217	CSNK2A2	ENSXMAP00000007876	ENSXMAP00000032258	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.	0.943