STRINGSTRING
LOC111611362 LOC111611362 rps27a rps27a LOC102235594 LOC102235594 skil skil itgb8 itgb8 furin furin zfyve9 zfyve9 LOC102216881 LOC102216881 itgb6 itgb6 LOC102234947 LOC102234947 e2f4 e2f4 FBN1 FBN1 LOC102238136 LOC102238136 LOC102223216 LOC102223216 smad3 smad3 parp1 parp1 cdk9 cdk9 Uba52 Uba52 TGFB3 TGFB3 LOC102224322 LOC102224322 cdk19 cdk19 LOC102228719 LOC102228719 LOC102233360 LOC102233360 itgb5 itgb5 ncor1 ncor1 LOC102236989 LOC102236989 mapk1 mapk1 cgn cgn ccnc ccnc M3ZZL9_XIPMA M3ZZL9_XIPMA irx6 irx6 LOC102229697 LOC102229697 men1 men1 LOC102234136 LOC102234136 LOC102233950 LOC102233950 cbl cbl kxd1 kxd1 LOC102228037 LOC102228037 cdk8 cdk8 snw1 snw1 tfdp1 tfdp1 meis1 meis1 LOC111607616 LOC111607616 LOC102227933 LOC102227933 LOC102222703 LOC102222703 LOC111609651 LOC111609651 LOC102223745 LOC102223745 TGFBR2 TGFBR2 rbl1 rbl1 tgfb3 tgfb3 LOC102223661 LOC102223661 LOC102222190 LOC102222190 LOC102224049 LOC102224049 sp1 sp1 LOC102219610 LOC102219610 LOC102224124 LOC102224124 LOC102237417 LOC102237417 LOC102229617 LOC102229617 smad2 smad2 LOC102225323 LOC102225323 ldlrad4 ldlrad4 ENSXMAP00000022599 ENSXMAP00000022599 ubb ubb LTBP3 LTBP3 LOC102238111 LOC102238111 ENSXMAP00000023904 ENSXMAP00000023904 SMURF2 SMURF2 LOC102229696 LOC102229696 LOC102231627 LOC102231627 ski ski ENSXMAP00000026764 ENSXMAP00000026764 irx1 irx1 LOC111606295 LOC111606295 LOC102237032 LOC102237032 ltbp2 ltbp2 ccnq ccnq LOC102231514 LOC102231514 LOC102222459 LOC102222459 meis2 meis2 irx5 irx5 rnf111 rnf111 PARD3 PARD3 SMAD4 SMAD4 ENSXMAP00000031631 ENSXMAP00000031631 atp1b4 atp1b4 strap strap LOC102232128 LOC102232128 LOC102221802 LOC102221802 fkbp1b fkbp1b stub1 stub1 ncor2 ncor2 smurf1 smurf1 LOC102235802 LOC102235802 LOC102237871 LOC102237871 itgb3 itgb3 LOC102226335 LOC102226335 irx2 irx2 ENSXMAP00000036141 ENSXMAP00000036141 ENSXMAP00000036468 ENSXMAP00000036468 ENSXMAP00000037217 ENSXMAP00000037217 nedd4l nedd4l smad7 smad7 bambi bambi LOC102237712 LOC102237712 LOC102233047 LOC102233047 ccnt2 ccnt2 irx3 irx3 ccnk ccnk LOC102222719 LOC102222719 prkcz prkcz arhgef18 arhgef18 SMAD3 SMAD3 ENSXMAP00000041178 ENSXMAP00000041178 LOC102228760 LOC102228760 LOC111606272 LOC111606272
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC111611362Iroquois-class homeodomain protein irx-4-B-like. (476 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC102235594NEDD8 ubiquitin like modifier. (79 aa)
skilSKI-like proto-oncogene a. (771 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (760 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (844 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1167 aa)
LOC102216881Transforming growth factor beta; Belongs to the TGF-beta family. (394 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (665 aa)
LOC102234947Par-3 family cell polarity regulator beta b. (1206 aa)
e2f4E2F transcription factor 4. (389 aa)
FBN1Fibrillin 1. (2818 aa)
LOC102238136Myeloid ecotropic viral integration site 3. (419 aa)
LOC102223216Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
cdk9Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
Uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (355 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
LOC102224322Mothers against decapentaplegic homolog. (467 aa)
cdk19Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (449 aa)
LOC102228719Mothers against decapentaplegic homolog. (503 aa)
LOC102233360Iroquois homeobox 4a. (476 aa)
itgb5Integrin beta; Belongs to the integrin beta chain family. (797 aa)
ncor1Nuclear receptor corepressor 1. (2164 aa)
LOC102236989Par-3 family cell polarity regulator alpha, b. (1386 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
cgnCingulin a. (1198 aa)
ccncCyclin C; Belongs to the cyclin family. (305 aa)
M3ZZL9_XIPMAE2F transcription factor 5. (159 aa)
irx6Iroquois homeobox 6a. (476 aa)
LOC102229697CYCLIN domain-containing protein; Belongs to the cyclin family. (175 aa)
men1Multiple endocrine neoplasia I. (626 aa)
LOC102234136SMAD specific E3 ubiquitin protein ligase 2. (722 aa)
LOC102233950Uncharacterized protein. (858 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (953 aa)
kxd1KxDL motif containing 1. (184 aa)
LOC102228037Cyclin T1; Belongs to the cyclin family. (668 aa)
cdk8Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (464 aa)
snw1SNW domain containing 1. (536 aa)
tfdp1Transcription factor. (410 aa)
meis1Meis homeobox 1 b. (409 aa)
LOC111607616Par-3 family cell polarity regulator beta a. (1266 aa)
LOC102227933Iroquois homeobox 7. (323 aa)
LOC102222703Tripartite motif containing 33. (1297 aa)
LOC111609651Si:dkey-235d18.5. (598 aa)
LOC102223745Iroquois homeobox 4b. (392 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (539 aa)
rbl1Retinoblastoma-like 1 (p107). (1055 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC102223661Uncharacterized protein. (1526 aa)
LOC102222190Peptidylprolyl isomerase. (108 aa)
LOC102224049V-ski avian sarcoma viral oncogene homolog b. (698 aa)
sp1Sp1 transcription factor. (658 aa)
LOC102219610Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2490 aa)
LOC102224124Homeobox domain-containing protein. (379 aa)
LOC102237417JunB proto-oncogene, AP-1 transcription factor subunit a. (330 aa)
LOC102229617Ubiquitin-like domain-containing protein. (83 aa)
smad2Mothers against decapentaplegic homolog. (474 aa)
LOC102225323Mothers against decapentaplegic homolog. (563 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (326 aa)
ENSXMAP00000022599Uncharacterized protein. (289 aa)
ubbUbiquitin B. (838 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1234 aa)
LOC102238111Homeobox domain-containing protein. (535 aa)
ENSXMAP00000023904Latent transforming growth factor beta binding protein 1. (1106 aa)
SMURF2E3 ubiquitin-protein ligase. (776 aa)
LOC102229696Par-6 family cell polarity regulator alpha. (422 aa)
LOC102231627Iroquois homeobox 1a. (492 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (718 aa)
ENSXMAP00000026764Uncharacterized protein. (597 aa)
irx1Homeobox domain-containing protein. (442 aa)
LOC111606295Mohawk homeobox a. (359 aa)
LOC102237032Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
ltbp2Uncharacterized protein. (1631 aa)
ccnqCyclin Q; Belongs to the cyclin family. (233 aa)
LOC102231514Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (598 aa)
LOC102222459Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (805 aa)
meis2Meis homeobox 2a. (470 aa)
irx5Iroquois homeobox 5a. (452 aa)
rnf111Ring finger protein 111. (1021 aa)
PARD3Par-3 family cell polarity regulator. (1396 aa)
SMAD4Mothers against decapentaplegic homolog. (512 aa)
ENSXMAP00000031631Integrin_b_cyt domain-containing protein. (97 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (338 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
LOC102232128Prostate transmembrane protein, androgen induced 1. (324 aa)
LOC102221802Integrin beta; Belongs to the integrin beta chain family. (791 aa)
fkbp1bPeptidylprolyl isomerase. (110 aa)
stub1STIP1 homology and U-Box containing protein 1. (284 aa)
ncor2Nuclear receptor corepressor 2. (2323 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
LOC102235802TGFB-induced factor homeobox 1. (327 aa)
LOC102237871F11 receptor, tandem duplicate 1. (300 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (792 aa)
LOC102226335Peptidylprolyl isomerase. (177 aa)
irx2Iroquois homeobox 2a. (508 aa)
ENSXMAP00000036141Ubiquitin-like domain-containing protein. (75 aa)
ENSXMAP00000036468Uncharacterized protein. (103 aa)
ENSXMAP00000037217Uncharacterized protein. (264 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1014 aa)
smad7Mothers against decapentaplegic homolog. (378 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
LOC102237712Cbl proto-oncogene C, E3 ubiquitin protein ligase. (566 aa)
LOC102233047Homeobox domain-containing protein. (401 aa)
ccnt2Cyclin T2; Belongs to the cyclin family. (682 aa)
irx3Iroquois homeobox 3a. (450 aa)
ccnkCyclin K; Belongs to the cyclin family. (541 aa)
LOC102222719Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
prkczProtein kinase C. (564 aa)
arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1697 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSXMAP00000041178E2F transcription factor 5. (149 aa)
LOC102228760Mohawk homeobox b. (400 aa)
LOC111606272Mohawk homeobox a. (343 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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