(50 nodes) snRNP Assembly network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prmt5	Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (652 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	tpr	Translocated promoter region b, nuclear basket protein. (2281 aa)
	seh1l	SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (383 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	nup153	Nucleoporin 153. (1493 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	clns1a	Chloride channel, nucleotide-sensitive, 1A. (250 aa)
	nup155	Nucleoporin 155. (1346 aa)
	NUP62	Nucleoporin 62. (549 aa)
	nup188	Nucleoporin 188. (1628 aa)
	M3ZX48_XIPMA	Uncharacterized protein. (352 aa)
	WDR77	WD repeat domain 77. (334 aa)
	ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (766 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	gemin2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (258 aa)
	nup50	Nucleoporin 50. (446 aa)
	LOC102236588	Nucleoporin 42. (425 aa)
	nup214	Nup214_FG domain-containing protein. (1990 aa)
	ndc1	NDC1 transmembrane nucleoporin. (669 aa)
	pom121	POM121 transmembrane nucleoporin. (1160 aa)
	nup133	Nucleoporin 133. (1138 aa)
	nup85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (654 aa)
	Snrpf	Small nuclear ribonucleoprotein polypeptide F. (85 aa)
	M4AWA9_XIPMA	Translocated promoter region a, nuclear basket protein. (1776 aa)
	sec13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
	gemin7	Gem (nuclear organelle) associated protein 7. (128 aa)
	nup88	Nucleoporin 88. (721 aa)
	nup37	Nucleoporin 37. (326 aa)
	ENSXMAP00000021805	Uncharacterized protein. (210 aa)
	nup93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (820 aa)
	ENSXMAP00000022713	Small nuclear ribonucleoprotein-associated protein. (234 aa)
	ENSXMAP00000023550	Peptidase S59 domain-containing protein. (211 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1445 aa)
	rae1	Ribonucleic acid export 1. (369 aa)
	ENSXMAP00000024626	Uncharacterized protein. (312 aa)
	gemin8	Gem (nuclear organelle) associated protein 8. (194 aa)
	nup43	Nucleoporin 43. (370 aa)
	aaas	Achalasia, adrenocortical insufficiency, alacrimia. (518 aa)
	Nup98	Nup96 domain-containing protein. (374 aa)
	nup35	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (296 aa)
	nup58	Nucleoporin 58. (594 aa)
	LOC102218559	RAN binding protein 2. (2916 aa)
	nup210	Nucleoporin 210. (1881 aa)
	LOC102216861	Survival of motor neuron 1, telomeric. (283 aa)
	snupn	Snurportin 1. (372 aa)
	gemin4	Gem (nuclear organelle) associated protein 4. (1121 aa)
	nup160	Nucleoporin 160. (1416 aa)
	NUP54	Nucleoporin 54. (621 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000021805	ENSXMAP00000023550	ENSXMAP00000021805	ENSXMAP00000023550	Uncharacterized protein.	Peptidase S59 domain-containing protein.	0.955
ENSXMAP00000021805	ENSXMAP00000024626	ENSXMAP00000021805	ENSXMAP00000024626	Uncharacterized protein.	Uncharacterized protein.	0.985
ENSXMAP00000021805	LOC102218559	ENSXMAP00000021805	ENSXMAP00000034618	Uncharacterized protein.	RAN binding protein 2.	0.999
ENSXMAP00000021805	LOC102236588	ENSXMAP00000021805	ENSXMAP00000010673	Uncharacterized protein.	Nucleoporin 42.	0.596
ENSXMAP00000021805	M3ZX48_XIPMA	ENSXMAP00000021805	ENSXMAP00000006792	Uncharacterized protein.	Uncharacterized protein.	0.955
ENSXMAP00000021805	M4AWA9_XIPMA	ENSXMAP00000021805	ENSXMAP00000018754	Uncharacterized protein.	Translocated promoter region a, nuclear basket protein.	0.916
ENSXMAP00000021805	NUP54	ENSXMAP00000021805	ENSXMAP00000041182	Uncharacterized protein.	Nucleoporin 54.	0.986
ENSXMAP00000021805	NUP62	ENSXMAP00000021805	ENSXMAP00000005170	Uncharacterized protein.	Nucleoporin 62.	0.979
ENSXMAP00000021805	Nup98	ENSXMAP00000021805	ENSXMAP00000032029	Uncharacterized protein.	Nup96 domain-containing protein.	0.955
ENSXMAP00000021805	Snrpf	ENSXMAP00000021805	ENSXMAP00000015470	Uncharacterized protein.	Small nuclear ribonucleoprotein polypeptide F.	0.510
ENSXMAP00000021805	WDR77	ENSXMAP00000021805	ENSXMAP00000007192	Uncharacterized protein.	WD repeat domain 77.	0.554
ENSXMAP00000021805	aaas	ENSXMAP00000021805	ENSXMAP00000029480	Uncharacterized protein.	Achalasia, adrenocortical insufficiency, alacrimia.	0.977
ENSXMAP00000021805	ddx20	ENSXMAP00000021805	ENSXMAP00000007598	Uncharacterized protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.565
ENSXMAP00000021805	gemin4	ENSXMAP00000021805	ENSXMAP00000040514	Uncharacterized protein.	Gem (nuclear organelle) associated protein 4.	0.472
ENSXMAP00000021805	gemin5	ENSXMAP00000021805	ENSXMAP00000023967	Uncharacterized protein.	Gem (nuclear organelle) associated protein 5.	0.508
ENSXMAP00000021805	gemin8	ENSXMAP00000021805	ENSXMAP00000027460	Uncharacterized protein.	Gem (nuclear organelle) associated protein 8.	0.534
ENSXMAP00000021805	ndc1	ENSXMAP00000021805	ENSXMAP00000012914	Uncharacterized protein.	NDC1 transmembrane nucleoporin.	0.954
ENSXMAP00000021805	nup133	ENSXMAP00000021805	ENSXMAP00000014178	Uncharacterized protein.	Nucleoporin 133.	0.999
ENSXMAP00000021805	nup153	ENSXMAP00000021805	ENSXMAP00000003443	Uncharacterized protein.	Nucleoporin 153.	0.982
ENSXMAP00000021805	nup155	ENSXMAP00000021805	ENSXMAP00000005128	Uncharacterized protein.	Nucleoporin 155.	0.987