57 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ppp4r1	WRNPLPNID domain-containing protein. (970 aa)
	LOC102227958	Chromodomain helicase DNA binding protein 4a. (1585 aa)
	LOC102216396	Activating transcription factor 1. (310 aa)
	LOC102222342	Tribbles pseudokinase 1. (361 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (389 aa)
	LOC102217254	Ribosomal protein S6 kinase. (783 aa)
	LOC102225341	cAMP responsive element modulator a. (111 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC102223777	Serine/threonine-protein phosphatase. (309 aa)
	LOC102223674	Mitogen-activated protein kinase. (361 aa)
	LOC102218102	Mitogen-activated protein kinase. (357 aa)
	nab1	NGFI-A binding protein 1a (EGR1 binding protein 1). (508 aa)
	LOC102236567	Uncharacterized protein. (1780 aa)
	fosl1	FOS-like antigen 1a. (337 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1064 aa)
	egr2	Early growth response 2b. (446 aa)
	vrk3	VRK serine/threonine kinase 3. (527 aa)
	LOC102220269	Ribosomal protein S6 kinase. (794 aa)
	LOC102229921	Ribosomal protein S6 kinase. (775 aa)
	LOC102236340	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (366 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (219 aa)
	LOC102234393	Inhibitor of DNA binding 3. (116 aa)
	LOC102235687	Ribosomal protein S6 kinase. (769 aa)
	fnbp4	Formin binding protein 4. (877 aa)
	LOC102237417	JunB proto-oncogene, AP-1 transcription factor subunit a. (330 aa)
	ascl1	Achaete-scute family bHLH transcription factor 1a. (199 aa)
	M4AZP2_XIPMA	Achaete-scute family bHLH transcription factor 1b. (179 aa)
	JUND	BZIP domain-containing protein. (314 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
	LOC102231047	Mitogen-activated protein kinase. (360 aa)
	SRF	Serum response factor. (597 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1189 aa)
	LOC102237594	BHLH domain-containing protein. (458 aa)
	LOC102223904	Inhibitor of DNA binding 4. (154 aa)
	LOC102221737	cAMP responsive element binding protein 1. (317 aa)
	LOC102225341-2	KID domain-containing protein. (223 aa)
	ppp4r4	Protein phosphatase 4, regulatory subunit 4. (908 aa)
	LOC102237032	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	egr3	Early growth response 3. (410 aa)
	SGK1	Non-specific serine/threonine protein kinase. (612 aa)
	ENSXMAP00000032717	Protein kinase domain-containing protein. (97 aa)
	ENSXMAP00000032804	BZIP domain-containing protein. (108 aa)
	elk1	ETS transcription factor ELK1. (527 aa)
	ENSXMAP00000033891	BZIP domain-containing protein. (90 aa)
	LOC102233752	Mitogen-activated protein kinase. (435 aa)
	nab2	NGFI-A binding protein 2 (EGR1 binding protein 2). (499 aa)
	LOC102229912	MADS-box domain-containing protein. (469 aa)
	dusp7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	mapkapk2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (376 aa)
	mapk15	Mitogen-activated protein kinase. (611 aa)
	trib2	Tribbles pseudokinase 2. (344 aa)
	creb1	Uncharacterized protein. (351 aa)
	LOC102223324	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (227 aa)
	ENSXMAP00000041640	Si:dkey-23i12.7. (128 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP3	LOC102218102	ENSXMAP00000017930	ENSXMAP00000010371	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102223324	ENSXMAP00000017930	ENSXMAP00000040198	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.901
DUSP3	LOC102223674	ENSXMAP00000017930	ENSXMAP00000010282	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102231047	ENSXMAP00000017930	ENSXMAP00000021619	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102233752	ENSXMAP00000017930	ENSXMAP00000034299	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102237032	ENSXMAP00000017930	ENSXMAP00000028528	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.945
DUSP3	mapk1	ENSXMAP00000017930	ENSXMAP00000006468	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.945
DUSP3	mapk7	ENSXMAP00000017930	ENSXMAP00000013808	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.476
DUSP3	vrk3	ENSXMAP00000017930	ENSXMAP00000014252	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	VRK serine/threonine kinase 3.	0.550
ENSXMAP00000032717	ENSXMAP00000032804	ENSXMAP00000032717	ENSXMAP00000032804	Protein kinase domain-containing protein.	BZIP domain-containing protein.	0.442
ENSXMAP00000032717	LOC102216396	ENSXMAP00000032717	ENSXMAP00000002221	Protein kinase domain-containing protein.	Activating transcription factor 1.	0.442
ENSXMAP00000032717	LOC102221737	ENSXMAP00000032717	ENSXMAP00000024327	Protein kinase domain-containing protein.	cAMP responsive element binding protein 1.	0.478
ENSXMAP00000032717	LOC102225341	ENSXMAP00000032717	ENSXMAP00000006374	Protein kinase domain-containing protein.	cAMP responsive element modulator a.	0.450
ENSXMAP00000032717	LOC102225341-2	ENSXMAP00000032717	ENSXMAP00000025696	Protein kinase domain-containing protein.	KID domain-containing protein.	0.450
ENSXMAP00000032717	creb1	ENSXMAP00000032717	ENSXMAP00000039297	Protein kinase domain-containing protein.	Uncharacterized protein.	0.450
ENSXMAP00000032804	ENSXMAP00000032717	ENSXMAP00000032804	ENSXMAP00000032717	BZIP domain-containing protein.	Protein kinase domain-containing protein.	0.442
ENSXMAP00000032804	LOC102217254	ENSXMAP00000032804	ENSXMAP00000005281	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.565
ENSXMAP00000032804	LOC102220269	ENSXMAP00000032804	ENSXMAP00000014403	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.483
ENSXMAP00000032804	LOC102229921	ENSXMAP00000032804	ENSXMAP00000015765	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.565
ENSXMAP00000032804	LOC102235687	ENSXMAP00000032804	ENSXMAP00000018960	BZIP domain-containing protein.	Ribosomal protein S6 kinase.	0.483