STRINGSTRING
M3ZCY4_XIPMA M3ZCY4_XIPMA fam102b fam102b LOC102232368 LOC102232368 fgf3 fgf3 fgf19 fgf19 fgf1 fgf1 LOC102231120 LOC102231120 erbb3 erbb3 LOC102217013 LOC102217013 fgf7 fgf7 M3ZJA3_XIPMA M3ZJA3_XIPMA LOC102236577 LOC102236577 LOC102237875 LOC102237875 esr1 esr1 ppp2r1b ppp2r1b FGF6 FGF6 hgf hgf LOC102225882 LOC102225882 grb2 grb2 LOC102220089 LOC102220089 LOC102231273 LOC102231273 mapk1 mapk1 STRN STRN akt1 akt1 LOC102223754 LOC102223754 ppp2r5c ppp2r5c pik3ap1 pik3ap1 lrrc40 lrrc40 LOC102225368 LOC102225368 ppp2ca ppp2ca klb klb kl kl LOC111610852 LOC111610852 pdgfrb pdgfrb LOC102218230 LOC102218230 LOC102226090 LOC102226090 ppp2r5b ppp2r5b LOC102228937 LOC102228937 M4A2Z4_XIPMA M4A2Z4_XIPMA fndc3b fndc3b strn3 strn3 LOC102223777 LOC102223777 M4A4T1_XIPMA M4A4T1_XIPMA M4A4T4_XIPMA M4A4T4_XIPMA LOC102233809 LOC102233809 LOC102233390 LOC102233390 vtcn1 vtcn1 hbegf hbegf fgf10 fgf10 LOC102232343 LOC102232343 LOC102226637 LOC102226637 ppp4r1 ppp4r1 LOC102218636 LOC102218636 LOC102220912 LOC102220912 traf6 traf6 akt2 akt2 LOC102232076 LOC102232076 INSC INSC pten pten kit kit LOC102224088 LOC102224088 LOC102216436 LOC102216436 pdgfra pdgfra met met il1rap il1rap LOC102235425 LOC102235425 LOC102226863 LOC102226863 PIP5K1A PIP5K1A gab2 gab2 tgfa tgfa LOC102231767 LOC102231767 LOC102225656 LOC102225656 LOC102236062 LOC102236062 LOC102228479 LOC102228479 ppp2r5a ppp2r5a LOC102224365 LOC102224365 LOC102237809 LOC102237809 pik3r1 pik3r1 LOC102227076 LOC102227076 LOC102217478 LOC102217478 LOC102216451 LOC102216451 lck lck LOC102218168 LOC102218168 fnbp4 fnbp4 M4AZN9_XIPMA M4AZN9_XIPMA LOC111607689 LOC111607689 LOC111609260 LOC111609260 LOC102226157 LOC102226157 pip4k2a pip4k2a LOC102232383 LOC102232383 LOC102218549 LOC102218549 LOC102229304 LOC102229304 ppp2r5e ppp2r5e relch relch LOC102233791 LOC102233791 LOC102231629 LOC102231629 pik3cb pik3cb LOC111609196 LOC111609196 insr insr pik3r3 pik3r3 LOC102225224 LOC102225224 LOC102221770 LOC102221770 LOC102219809 LOC102219809 SRC SRC pip5kl1 pip5kl1 LOC102225687 LOC102225687 LOC102231344 LOC102231344 fndc3a fndc3a LOC102233151 LOC102233151 ppp4r4 ppp4r4 gab1 gab1 LCT LCT PHLPP2 PHLPP2 LOC102217180 LOC102217180 FGF13 FGF13 LOC102237032 LOC102237032 ENSXMAP00000028632 ENSXMAP00000028632 PTEN PTEN LOC102222446 LOC102222446 erbb4 erbb4 LOC102235496 LOC102235496 LOC102236685 LOC102236685 FGF6-2 FGF6-2 LOC102225657 LOC102225657 LOC102229665 LOC102229665 LOC102232504 LOC102232504 ENSXMAP00000029934 ENSXMAP00000029934 ENSXMAP00000029947 ENSXMAP00000029947 pik3cd pik3cd LOC102224699 LOC102224699 ppp2cb ppp2cb pip5k1c pip5k1c lctl lctl fgf17 fgf17 ins ins LOC102232037 LOC102232037 LOC102236879 LOC102236879 LOC102225708 LOC102225708 ENSXMAP00000032566 ENSXMAP00000032566 pip4k2c pip4k2c LOC102217141 LOC102217141 fgf16 fgf16 LOC102227153 LOC102227153 fgf5 fgf5 LOC102228238 LOC102228238 LOC102237749 LOC102237749 fgf2 fgf2 LOC111606142 LOC111606142 morn2 morn2 fgf4 fgf4 LOC102237794 LOC102237794 LOC102230481 LOC102230481 PIP4K2B PIP4K2B myd88 myd88 frs2 frs2 LOC102237954 LOC102237954 fgf18 fgf18 LOC102227197 LOC102227197 ENSXMAP00000036386 ENSXMAP00000036386 LOC102233436 LOC102233436 erbb2 erbb2 btc btc flt3 flt3 ENSXMAP00000037713 ENSXMAP00000037713 irak4 irak4 pdgfa pdgfa LOC102223666 LOC102223666 Ppp2r5d Ppp2r5d LOC102232905 LOC102232905 cd276 cd276 strn4 strn4 LOC102235349 LOC102235349 LOC102235704 LOC102235704
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
M3ZCY4_XIPMAUncharacterized protein; Belongs to the heparin-binding growth factors family. (90 aa)
fam102bFamily with sequence similarity 102 member Bb. (439 aa)
LOC102232368Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (522 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (248 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf1Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (167 aa)
LOC102231120PPM-type phosphatase domain-containing protein. (1684 aa)
erbb3Protein kinase domain-containing protein. (1413 aa)
LOC102217013Uncharacterized protein. (1848 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
M3ZJA3_XIPMAEpidermal growth factor. (946 aa)
LOC102236577Uncharacterized protein. (408 aa)
LOC102237875Family with sequence similarity 102 member Aa. (385 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (612 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
hgfHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (719 aa)
LOC102225882Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC102220089IGv domain-containing protein. (247 aa)
LOC102231273Tribbles pseudokinase 3. (351 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
STRNStriatin. (779 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
LOC102223754Ras homolog family member Gb. (191 aa)
ppp2r5cSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (525 aa)
pik3ap1Phosphoinositide-3-kinase adaptor protein 1. (872 aa)
lrrc40Leucine rich repeat containing 40. (597 aa)
LOC102225368Neuregulin 3b. (785 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
klbKlotho beta. (1051 aa)
klKlotho. (977 aa)
LOC111610852DBB domain-containing protein. (606 aa)
pdgfrbPlatelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1102 aa)
LOC102218230Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC102226090Family with sequence similarity 102 member Ba. (366 aa)
ppp2r5bSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (522 aa)
LOC102228937Melanoma receptor tyrosine-protein kinase; Probable receptor with tyrosine-protein kinase activity. (1167 aa)
M4A2Z4_XIPMAReceptor protein-tyrosine kinase. (1155 aa)
fndc3bFibronectin type III domain containing 3Ba. (1209 aa)
strn3Striatin, calmodulin binding protein 3. (704 aa)
LOC102223777Serine/threonine-protein phosphatase. (309 aa)
M4A4T1_XIPMAUncharacterized protein. (119 aa)
M4A4T4_XIPMARas homolog gene family, member Gd. (101 aa)
LOC102233809Fibroblast growth factor receptor 2. (1129 aa)
LOC102233390Tyrosine-protein kinase. (537 aa)
vtcn1V-set domain containing T cell activation inhibitor 1. (272 aa)
hbegfHeparin-binding EGF-like growth factor. (236 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
LOC102232343Epithelial mitogen homolog (mouse). (164 aa)
LOC102226637EGF-like domain-containing protein. (153 aa)
ppp4r1WRNPLPNID domain-containing protein. (970 aa)
LOC102218636PH domain-containing protein. (763 aa)
LOC102220912Crystallin, beta B1, like 3; Belongs to the beta/gamma-crystallin family. (254 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
LOC102232076Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (221 aa)
INSCINSC spindle orientation adaptor protein. (545 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (441 aa)
kitMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (978 aa)
LOC102224088Lactase-like a; Belongs to the glycosyl hydrolase 1 family. (565 aa)
LOC102216436Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (728 aa)
pdgfraPlatelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1457 aa)
metMET proto-oncogene, receptor tyrosine kinase. (1418 aa)
il1rapUncharacterized protein. (734 aa)
LOC102235425Uncharacterized protein. (726 aa)
LOC102226863Insulin receptor substrate 2a. (1061 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (595 aa)
gab2GRB2-associated binding protein 2. (676 aa)
tgfaTransforming growth factor, alpha. (245 aa)
LOC102231767Receptor protein-tyrosine kinase. (1376 aa)
LOC102225656Fibroblast growth factor receptor. (697 aa)
LOC102236062Receptor protein-tyrosine kinase. (1209 aa)
LOC102228479Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
ppp2r5aSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (515 aa)
LOC102224365Striatin, calmodulin binding protein. (780 aa)
LOC102237809Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (955 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
LOC102227076Tyrosine-protein kinase receptor. (1357 aa)
LOC102217478Kit ligand a. (270 aa)
LOC102216451Fibroblast growth factor receptor. (700 aa)
lckTyrosine-protein kinase. (500 aa)
LOC102218168PIPK domain-containing protein. (669 aa)
fnbp4Formin binding protein 4. (877 aa)
M4AZN9_XIPMAUncharacterized protein. (169 aa)
LOC111607689Uncharacterized protein. (224 aa)
LOC111609260Uncharacterized protein. (623 aa)
LOC102226157Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1152 aa)
pip4k2aPhosphatidylinositol-5-phosphate 4-kinase, type II, alpha a. (443 aa)
LOC102232383Thioesterase superfamily member 4. (282 aa)
LOC102218549Neuregulin 2a. (731 aa)
LOC102229304Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
ppp2r5eSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (478 aa)
relchRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1189 aa)
LOC102233791Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
LOC102231629Fibroblast growth factor receptor. (831 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
LOC111609196Uncharacterized protein. (406 aa)
insrTyrosine-protein kinase receptor. (1337 aa)
pik3r3Uncharacterized protein. (473 aa)
LOC102225224Family with sequence similarity 102 member Ab. (374 aa)
LOC102221770Estrogen receptor 2b. (668 aa)
LOC102219809Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (413 aa)
SRCTyrosine-protein kinase. (550 aa)
pip5kl1Phosphatidylinositol-4-phosphate 5-kinase-like 1. (461 aa)
LOC102225687PH domain and leucine rich repeat protein phosphatase 1. (1772 aa)
LOC102231344Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (265 aa)
fndc3aFibronectin type III domain containing 3A. (1239 aa)
LOC102233151Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
ppp4r4Protein phosphatase 4, regulatory subunit 4. (908 aa)
gab1GRB2-associated binding protein 1. (765 aa)
LCTLactase. (1830 aa)
PHLPP2PH domain and leucine rich repeat protein phosphatase 2. (1400 aa)
LOC102217180Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (579 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC102237032Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
ENSXMAP00000028632Uncharacterized protein. (125 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (447 aa)
LOC102222446Phosphatidylinositol-4-phosphate 5-kinase, type I, beta b. (573 aa)
erbb4Receptor protein-tyrosine kinase. (1450 aa)
LOC102235496Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
LOC102236685Neuregulin 2b. (714 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC102225657Phosphatidylinositol-4-phosphate 5-kinase, type I, beta a. (501 aa)
LOC102229665Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa)
LOC102232504Non-specific serine/threonine protein kinase. (503 aa)
ENSXMAP00000029934Protein phosphatase 2, regulatory subunit B', delta. (259 aa)
ENSXMAP00000029947EGF-like domain-containing protein. (104 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC102224699Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
pip5k1cPhosphatidylinositol-4-phosphate 5-kinase, type I, gamma a. (725 aa)
lctlLactase-like b; Belongs to the glycosyl hydrolase 1 family. (585 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (140 aa)
LOC102232037Estrogen receptor 2a. (579 aa)
LOC102236879Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (177 aa)
LOC102225708Erb-b2 receptor tyrosine kinase 3b. (1365 aa)
ENSXMAP00000032566Uncharacterized protein. (154 aa)
pip4k2cPhosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (419 aa)
LOC102217141Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (158 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
LOC102227153Insulin receptor substrate 2b. (1117 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa)
LOC102228238Fibroblast growth factor receptor. (815 aa)
LOC102237749Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (240 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC111606142Receptor protein-tyrosine kinase. (1132 aa)
morn2Uncharacterized protein. (133 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
LOC102237794Tyrosine-protein kinase. (537 aa)
LOC102230481Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (428 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
frs2Fibroblast growth factor receptor substrate 2b. (521 aa)
LOC102237954Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC102227197Tyrosine-protein kinase. (542 aa)
ENSXMAP00000036386EGF-like domain-containing protein. (96 aa)
LOC102233436Uncharacterized protein. (466 aa)
erbb2Receptor protein-tyrosine kinase. (1286 aa)
btcEGF-like domain-containing protein. (189 aa)
flt3Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1005 aa)
ENSXMAP00000037713Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (634 aa)
irak4Interleukin-1 receptor-associated kinase 4. (462 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (228 aa)
LOC102223666EGF-like domain-containing protein. (623 aa)
Ppp2r5dUncharacterized protein. (196 aa)
LOC102232905Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b. (647 aa)
cd276CD276 molecule. (298 aa)
strn4Striatin, calmodulin binding protein 4. (772 aa)
LOC102235349PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (570 aa)
LOC102235704Uncharacterized protein. (552 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: low (16%) [HD]