(26 nodes) Metabolism of nitric oxide: NOS3 activation and regulation network (Xiphophorus maculatus)

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Known Interactions

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Predicted Interactions

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Your Input:
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	nosip	Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. (300 aa)
	LOC102237893	FH2 domain-containing protein. (351 aa)
	LOC102236992	Cytoglobin 2; Belongs to the globin family. (175 aa)
	FMN1	Formin 1. (1299 aa)
	LOC102218115	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
	LOC102218377	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
	zdhhc21	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
	wasl	WASP like actin nucleation promoting factor a. (482 aa)
	spr	Sepiapterin reductase b. (265 aa)
	nostrin	Nitric oxide synthase trafficking. (576 aa)
	LOC102223910	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (860 aa)
	LOC102218425	Dimethylarginine dimethylaminohydrolase 2. (290 aa)
	was	WASP actin nucleation promoting factor a. (530 aa)
	LOC102219662	GLOBIN domain-containing protein; Belongs to the globin family. (177 aa)
	LOC102228105	WH1 domain-containing protein. (366 aa)
	DDAH1	Dimethylarginine dimethylaminohydrolase 1. (450 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC102221167	WASP like actin nucleation promoting factor b. (495 aa)
	LOC102232504	Non-specific serine/threonine protein kinase. (503 aa)
	LOC102221843	Formin 1. (1126 aa)
	recql	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (642 aa)
	LOC102231683	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa)
	LOC102237954	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC102235952	FH2 domain-containing protein. (1495 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102218115	LOC102218377	ENSXMAP00000008332	ENSXMAP00000008338	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.900
LOC102218115	LOC102232504	ENSXMAP00000008332	ENSXMAP00000029766	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Non-specific serine/threonine protein kinase.	0.673
LOC102218115	LOC102237954	ENSXMAP00000008332	ENSXMAP00000035637	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.673
LOC102218115	cav3	ENSXMAP00000008332	ENSXMAP00000038231	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.423
LOC102218115	spr	ENSXMAP00000008332	ENSXMAP00000010744	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	Sepiapterin reductase b.	0.519
LOC102218377	LOC102218115	ENSXMAP00000008338	ENSXMAP00000008332	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.900
LOC102218377	LOC102232504	ENSXMAP00000008338	ENSXMAP00000029766	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Non-specific serine/threonine protein kinase.	0.673
LOC102218377	LOC102237954	ENSXMAP00000008338	ENSXMAP00000035637	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.673
LOC102218377	cav3	ENSXMAP00000008338	ENSXMAP00000038231	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.423
LOC102218377	spr	ENSXMAP00000008338	ENSXMAP00000010744	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	Sepiapterin reductase b.	0.519
LOC102221167	LOC102223910	ENSXMAP00000029369	ENSXMAP00000012252	WASP like actin nucleation promoting factor b.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.476
LOC102221167	LOC102225266	ENSXMAP00000029369	ENSXMAP00000001534	WASP like actin nucleation promoting factor b.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.454
LOC102221167	LOC102231683	ENSXMAP00000029369	ENSXMAP00000033302	WASP like actin nucleation promoting factor b.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.476
LOC102221167	cav1	ENSXMAP00000029369	ENSXMAP00000025385	WASP like actin nucleation promoting factor b.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.502
LOC102221167	cav3	ENSXMAP00000029369	ENSXMAP00000038231	WASP like actin nucleation promoting factor b.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.578
LOC102221167	nostrin	ENSXMAP00000029369	ENSXMAP00000011866	WASP like actin nucleation promoting factor b.	Nitric oxide synthase trafficking.	0.585
LOC102223910	LOC102221167	ENSXMAP00000012252	ENSXMAP00000029369	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	WASP like actin nucleation promoting factor b.	0.476
LOC102223910	LOC102225266	ENSXMAP00000012252	ENSXMAP00000001534	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.500
LOC102223910	LOC102228105	ENSXMAP00000012252	ENSXMAP00000025043	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	WH1 domain-containing protein.	0.402
LOC102223910	cav1	ENSXMAP00000012252	ENSXMAP00000025385	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.563