38 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1306 aa)
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
	spns1	Spinster homolog 1 (Drosophila). (504 aa)
	LOC102216483	Ig-like domain-containing protein. (387 aa)
	LOC102231050	Ig-like domain-containing protein. (387 aa)
	LOC102233390	Tyrosine-protein kinase. (537 aa)
	LOC102218230	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	LOC111608140	Ig-like domain-containing protein. (550 aa)
	LOC102236431	Si:dkey-24p1.1. (1046 aa)
	LOC102235251	Polymeric immunoglobulin receptor. (335 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	LOC102225882	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	SHC4	SHC adaptor protein 4. (538 aa)
	LOC102229810	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1309 aa)
	LOC111608137	Uncharacterized protein. (636 aa)
	grap2	GRB2 related adaptor protein 2a. (288 aa)
	ENSXMAP00000040025	Ig-like domain-containing protein. (456 aa)
	LOC111608142	Ig-like domain-containing protein. (425 aa)
	LOC102234613	Spinster homolog 3 (Drosophila). (511 aa)
	vav2	Vav 2 guanine nucleotide exchange factor. (880 aa)
	LOC111608023	Uncharacterized protein. (1041 aa)
	LOC102237794	Tyrosine-protein kinase. (537 aa)
	LOC102235527	Uncharacterized protein. (1099 aa)
	ENSXMAP00000031522	Si:ch73-380l3.2. (294 aa)
	ENSXMAP00000031251	Uncharacterized protein. (339 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (864 aa)
	LOC102229675	Vav 3 guanine nucleotide exchange factor b. (862 aa)
	siglec15	Uncharacterized protein. (295 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (456 aa)
	LOC111608191	Uncharacterized protein. (508 aa)
	ENSXMAP00000024020	Uncharacterized protein. (1170 aa)
	syk	Tyrosine-protein kinase. (627 aa)
	tyrobp	Uncharacterized protein. (108 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (907 aa)
	LOC102226157	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1152 aa)
	lck	Tyrosine-protein kinase. (500 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (844 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	LOC102218230	ENSXMAP00000020890	ENSXMAP00000008625	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.533
CSDE1	LOC102225882	ENSXMAP00000020890	ENSXMAP00000004675	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.533
CSDE1	LOC102226157	ENSXMAP00000020890	ENSXMAP00000020887	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.533
CSDE1	LOC102233390	ENSXMAP00000020890	ENSXMAP00000009749	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.436
CSDE1	LOC102237794	ENSXMAP00000020890	ENSXMAP00000035149	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.436
CSDE1	SHC4	ENSXMAP00000020890	ENSXMAP00000002265	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 4.	0.419
CSDE1	grb2	ENSXMAP00000020890	ENSXMAP00000004986	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.673
CSDE1	lck	ENSXMAP00000020890	ENSXMAP00000019019	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.423
CSDE1	pik3cb	ENSXMAP00000020890	ENSXMAP00000022787	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.533
CSDE1	shc1	ENSXMAP00000020890	ENSXMAP00000026437	Cold shock domain containing E1, RNA-binding.	SHC (Src homology 2 domain containing) transforming protein 1.	0.419
ENSXMAP00000031251	tyrobp	ENSXMAP00000031251	ENSXMAP00000023372	Uncharacterized protein.	Uncharacterized protein.	0.424
ENSXMAP00000031522	tyrobp	ENSXMAP00000031522	ENSXMAP00000023372	Si:ch73-380l3.2.	Uncharacterized protein.	0.424
ENSXMAP00000040025	tyrobp	ENSXMAP00000040025	ENSXMAP00000023372	Ig-like domain-containing protein.	Uncharacterized protein.	0.411
LOC102216483	tyrobp	ENSXMAP00000010608	ENSXMAP00000023372	Ig-like domain-containing protein.	Uncharacterized protein.	0.424
LOC102218230	CSDE1	ENSXMAP00000008625	ENSXMAP00000020890	Zgc:158659; Belongs to the PI3/PI4-kinase family.	Cold shock domain containing E1, RNA-binding.	0.533
LOC102218230	LOC102229675	ENSXMAP00000008625	ENSXMAP00000026677	Zgc:158659; Belongs to the PI3/PI4-kinase family.	Vav 3 guanine nucleotide exchange factor b.	0.748
LOC102218230	LOC102229810	ENSXMAP00000008625	ENSXMAP00000001838	Zgc:158659; Belongs to the PI3/PI4-kinase family.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.757
LOC102218230	VAV1	ENSXMAP00000008625	ENSXMAP00000015628	Zgc:158659; Belongs to the PI3/PI4-kinase family.	Vav guanine nucleotide exchange factor 1.	0.748
LOC102218230	VAV3	ENSXMAP00000008625	ENSXMAP00000028041	Zgc:158659; Belongs to the PI3/PI4-kinase family.	Vav guanine nucleotide exchange factor 3.	0.748
LOC102218230	grap2	ENSXMAP00000008625	ENSXMAP00000000013	Zgc:158659; Belongs to the PI3/PI4-kinase family.	GRB2 related adaptor protein 2a.	0.440