55 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102225499	AP complex subunit beta. (953 aa)
	LOC102222615	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1793 aa)
	DNM1	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (641 aa)
	dcx	Uncharacterized protein. (350 aa)
	M4ADB4_XIPMA	ANK_REP_REGION domain-containing protein. (456 aa)
	LOC102223910	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (860 aa)
	dnm3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (830 aa)
	l1cam	L1 cell adhesion molecule, paralog a. (1262 aa)
	ENSXMAP00000032245	Death domain-containing protein. (126 aa)
	LOC102222365	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1557 aa)
	chl1	Cell adhesion molecule L1-like b. (1200 aa)
	pak1	Non-specific serine/threonine protein kinase. (559 aa)
	ENSXMAP00000039242	Si:ch211-1o7.3. (430 aa)
	ENSXMAP00000038886	Uncharacterized protein. (519 aa)
	nfasc	Neurofascin homolog (chicken) a. (1374 aa)
	LOC102227723	Uncharacterized protein. (351 aa)
	LOC102218752	Uncharacterized protein. (1285 aa)
	LOC102231683	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa)
	LOC102237800	Hemicentin 2. (4044 aa)
	LOC102229798	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (929 aa)
	cntn2	Contactin 2. (1034 aa)
	LOC102226400	Ankyrin 1, erythrocytic b. (1643 aa)
	hmcn1	Hemicentin 1. (5413 aa)
	sh3gl2	SH3 domain containing GRB2 like 2a, endophilin A1. (360 aa)
	LOC102220395	Uncharacterized protein. (1828 aa)
	ENSXMAP00000031612	Uncharacterized protein. (494 aa)
	ENSXMAP00000031262	ANK_REP_REGION domain-containing protein. (133 aa)
	ENSXMAP00000030930	Death domain-containing protein. (5769 aa)
	LOC102237689	Uncharacterized protein. (1179 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	map2k2	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
	PAK3	Non-specific serine/threonine protein kinase. (574 aa)
	LOC102237032	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
	dnm1	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (861 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
	NRCAM	Uncharacterized protein. (1331 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1239 aa)
	ENSXMAP00000023898	SH3 domain-containing protein. (93 aa)
	LOC102231625	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (834 aa)
	LOC102236976	Ankyrin 1, erythrocytic a. (1710 aa)
	gap43	Growth associated protein 43. (237 aa)
	MCMDC2	Minichromosome maintenance domain containing 2. (649 aa)
	LOC102231067	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (926 aa)
	LOC102230406	Uncharacterized protein. (1171 aa)
	LOC102233459	Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1749 aa)
	LOC102222452	Syndecan binding protein (syntenin) 2. (302 aa)
	lypla2	Lysophospholipase 2. (236 aa)
	nrcam	Neuronal cell adhesion molecule a. (1305 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1209 aa)
	ank2	Ankyrin 2. (1644 aa)
	ankdd1b	Ankyrin repeat and death domain containing 1B. (547 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
	M3ZRB4_XIPMA	GED domain-containing protein. (176 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNM1	ENSXMAP00000023898	ENSXMAP00000012861	ENSXMAP00000023898	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3 domain-containing protein.	0.593
DNM1	LOC102225499	ENSXMAP00000012861	ENSXMAP00000013423	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit beta.	0.558
DNM1	LOC102227723	ENSXMAP00000012861	ENSXMAP00000038290	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Uncharacterized protein.	0.593
DNM1	LOC102229798	ENSXMAP00000012861	ENSXMAP00000002768	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.600
DNM1	LOC102231067	ENSXMAP00000012861	ENSXMAP00000001071	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.459
DNM1	M3ZRB4_XIPMA	ENSXMAP00000012861	ENSXMAP00000004757	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	GED domain-containing protein.	0.792
DNM1	ap2m1	ENSXMAP00000012861	ENSXMAP00000029293	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.558
DNM1	ap2s1	ENSXMAP00000012861	ENSXMAP00000004239	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.492
DNM1	clta	ENSXMAP00000012861	ENSXMAP00000026246	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.523
DNM1	sh3gl2	ENSXMAP00000012861	ENSXMAP00000032012	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	SH3 domain containing GRB2 like 2a, endophilin A1.	0.593
ENSXMAP00000023898	DNM1	ENSXMAP00000023898	ENSXMAP00000012861	SH3 domain-containing protein.	Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.593
ENSXMAP00000023898	LOC102223910	ENSXMAP00000023898	ENSXMAP00000012252	SH3 domain-containing protein.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.595
ENSXMAP00000023898	LOC102225499	ENSXMAP00000023898	ENSXMAP00000013423	SH3 domain-containing protein.	AP complex subunit beta.	0.450
ENSXMAP00000023898	LOC102229798	ENSXMAP00000023898	ENSXMAP00000002768	SH3 domain-containing protein.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.584
ENSXMAP00000023898	LOC102231625	ENSXMAP00000023898	ENSXMAP00000018308	SH3 domain-containing protein.	Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.593
ENSXMAP00000023898	LOC102231683	ENSXMAP00000023898	ENSXMAP00000033302	SH3 domain-containing protein.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.599
ENSXMAP00000023898	LOC102237032	ENSXMAP00000023898	ENSXMAP00000028528	SH3 domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.433
ENSXMAP00000023898	M3ZRB4_XIPMA	ENSXMAP00000023898	ENSXMAP00000004757	SH3 domain-containing protein.	GED domain-containing protein.	0.593
ENSXMAP00000023898	ap2m1	ENSXMAP00000023898	ENSXMAP00000029293	SH3 domain-containing protein.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.567
ENSXMAP00000023898	ap2s1	ENSXMAP00000023898	ENSXMAP00000004239	SH3 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.506