59 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	txndc5	Thioredoxin domain containing 5; Belongs to the protein disulfide isomerase family. (412 aa)
	ap4b1	Adaptor related protein complex 4 subunit beta 1. (800 aa)
	ctsz	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	SULF2	Sulfatase 2. (833 aa)
	LOC102227528	Si:ch211-11n16.2. (655 aa)
	dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6. (877 aa)
	LOC102230901	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
	ap1m1	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (423 aa)
	M3ZDQ5_XIPMA	Vesicle-associated membrane protein 2. (103 aa)
	clvs2	Clavesin 2. (355 aa)
	zfyve19	Zinc finger, FYVE domain containing 19. (425 aa)
	ap4e1	Adaptor related protein complex 4 subunit epsilon 1. (836 aa)
	ap4m1	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (442 aa)
	LOC102234718	Zinc finger, FYVE domain containing 1. (776 aa)
	cltb	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (215 aa)
	LOC102225782	Uncharacterized protein. (278 aa)
	M4AAD5_XIPMA	Zgc:92912. (125 aa)
	LOC102225969	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	LOC102232862	Amyloid beta (A4) precursor protein b. (752 aa)
	LOC102223910	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (860 aa)
	CLVS1	Clavesin 1. (328 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (772 aa)
	dnase2	Deoxyribonuclease II, lysosomal. (379 aa)
	LOC102234294	Arrestin, beta 1. (417 aa)
	ZFYVE1	Uncharacterized protein. (783 aa)
	tbrg4	Transforming growth factor beta regulator 4. (634 aa)
	chmp2a	Charged multivesicular body protein 2A. (221 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
	LOC102220326	Deoxyribonuclease II beta. (352 aa)
	LOC102224851	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (520 aa)
	arrb2	Arrestin, beta 2a. (494 aa)
	LOC111610521	Vesicle-associated membrane protein 1. (119 aa)
	m6pr	Mannose-6-phosphate receptor (cation dependent). (276 aa)
	ENSXMAP00000023898	SH3 domain-containing protein. (93 aa)
	LOC102232031	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
	LOC102233820	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (170 aa)
	gns	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (534 aa)
	ENSXMAP00000025967	Uncharacterized protein. (94 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
	ap1g1	AP-1 complex subunit gamma. (820 aa)
	LOC102224842	Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family. (423 aa)
	APP	Amyloid beta precursor protein. (763 aa)
	rsph9	Radial spoke head 9 homolog. (275 aa)
	sh3gl2	SH3 domain containing GRB2 like 2a, endophilin A1. (360 aa)
	sulf1	Sulfatase 1. (1146 aa)
	LOC102222582	Extracellular sulfatase. (885 aa)
	ap1m2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (436 aa)
	LOC102231683	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (885 aa)
	ENSXMAP00000034409	Adaptin_N domain-containing protein. (215 aa)
	vamp7	Synaptobrevin-like 1; Belongs to the synaptobrevin family. (220 aa)
	LOC102220591	Uncharacterized protein. (357 aa)
	ap5m1	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (517 aa)
	LOC102227723	Uncharacterized protein. (351 aa)
	LOC102229676	Vesicle-associated membrane protein 8 (endobrevin). (122 aa)
	ap4s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (144 aa)
	ENSXMAP00000039056	V-SNARE coiled-coil homology domain-containing protein. (103 aa)
	LOC102231073	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (202 aa)
	ap1s3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (156 aa)
	LOC102219080	AP-1 complex subunit gamma. (794 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP1S2	ENSXMAP00000025967	ENSXMAP00000015887	ENSXMAP00000025967	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Uncharacterized protein.	0.639
AP1S2	ENSXMAP00000034409	ENSXMAP00000015887	ENSXMAP00000034409	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptin_N domain-containing protein.	0.672
AP1S2	LOC102219080	ENSXMAP00000015887	ENSXMAP00000040034	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit gamma.	0.840
AP1S2	LOC102224842	ENSXMAP00000015887	ENSXMAP00000030170	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.	0.803
AP1S2	LOC102224851	ENSXMAP00000015887	ENSXMAP00000019024	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.	0.431
AP1S2	ap1g1	ENSXMAP00000015887	ENSXMAP00000029725	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit gamma.	0.862
AP1S2	ap1m1	ENSXMAP00000015887	ENSXMAP00000000639	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.803
AP1S2	ap1m2	ENSXMAP00000015887	ENSXMAP00000032951	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.805
AP1S2	ap4b1	ENSXMAP00000015887	ENSXMAP00000004405	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptor related protein complex 4 subunit beta 1.	0.830
AP1S2	ap4e1	ENSXMAP00000015887	ENSXMAP00000006788	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptor related protein complex 4 subunit epsilon 1.	0.672
AP1S2	ap4m1	ENSXMAP00000015887	ENSXMAP00000006791	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.803
AP1S2	ap5m1	ENSXMAP00000015887	ENSXMAP00000036862	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	0.615
AP1S2	clta	ENSXMAP00000015887	ENSXMAP00000026246	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.659
AP1S2	cltb	ENSXMAP00000015887	ENSXMAP00000009891	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.659
AP1S2	dnajc6	ENSXMAP00000015887	ENSXMAP00000002245	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	DnaJ (Hsp40) homolog, subfamily C, member 6.	0.611
AP1S2	gns	ENSXMAP00000015887	ENSXMAP00000025542	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.	0.431
AP1S2	rsph9	ENSXMAP00000015887	ENSXMAP00000030957	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Radial spoke head 9 homolog.	0.615
AP1S2	vamp7	ENSXMAP00000015887	ENSXMAP00000034575	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Synaptobrevin-like 1; Belongs to the synaptobrevin family.	0.413
APP	ap4b1	ENSXMAP00000030447	ENSXMAP00000004405	Amyloid beta precursor protein.	Adaptor related protein complex 4 subunit beta 1.	0.472
APP	ap4s1	ENSXMAP00000030447	ENSXMAP00000038684	Amyloid beta precursor protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.470