47 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
	LOC102223777	Serine/threonine-protein phosphatase. (309 aa)
	LOC102223674	Mitogen-activated protein kinase. (361 aa)
	ppp4r1	WRNPLPNID domain-containing protein. (970 aa)
	atf7	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (488 aa)
	LOC102218102	Mitogen-activated protein kinase. (357 aa)
	LOC102220269	Ribosomal protein S6 kinase. (794 aa)
	LOC102229921	Ribosomal protein S6 kinase. (775 aa)
	vrk3	VRK serine/threonine kinase 3. (527 aa)
	creb5	cAMP responsive element binding protein 5b. (509 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1064 aa)
	LOC102236340	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (366 aa)
	DUSP3	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (219 aa)
	LOC102235687	Ribosomal protein S6 kinase. (769 aa)
	fnbp4	Formin binding protein 4. (877 aa)
	LOC102231047	Mitogen-activated protein kinase. (360 aa)
	atf2	Activating transcription factor 2. (521 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1189 aa)
	ENSXMAP00000023172	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (288 aa)
	LOC102237941	Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (504 aa)
	LOC102221737	cAMP responsive element binding protein 1. (317 aa)
	LOC102237237	Mitogen-activated protein kinase. (420 aa)
	LOC102225341-2	KID domain-containing protein. (223 aa)
	ppp4r4	Protein phosphatase 4, regulatory subunit 4. (908 aa)
	LOC102237032	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	ENSXMAP00000032804	BZIP domain-containing protein. (108 aa)
	elk1	ETS transcription factor ELK1. (527 aa)
	LOC102233752	Mitogen-activated protein kinase. (435 aa)
	mapk8	Mitogen-activated protein kinase. (384 aa)
	dusp7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
	LOC102234094	Mitogen-activated protein kinase. (457 aa)
	mapkapk2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (376 aa)
	mapk15	Mitogen-activated protein kinase. (611 aa)
	creb1	Uncharacterized protein. (351 aa)
	LOC102223324	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (227 aa)
	LOC102223022	V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (381 aa)
	LOC102237102	BZIP domain-containing protein. (545 aa)
	LOC102216396	Activating transcription factor 1. (310 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	LOC102226271	JunE proto-oncogene, AP-1 transcription factor subunit. (324 aa)
	LOC102224057	V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (364 aa)
	mapk10	Mitogen-activated protein kinase. (401 aa)
	dusp6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (389 aa)
	LOC102217254	Ribosomal protein S6 kinase. (783 aa)
	LOC102225341	cAMP responsive element modulator a. (111 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP3	LOC102218102	ENSXMAP00000017930	ENSXMAP00000010371	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102223324	ENSXMAP00000017930	ENSXMAP00000040198	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.901
DUSP3	LOC102223674	ENSXMAP00000017930	ENSXMAP00000010282	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102231047	ENSXMAP00000017930	ENSXMAP00000021619	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102233752	ENSXMAP00000017930	ENSXMAP00000034299	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.780
DUSP3	LOC102234094	ENSXMAP00000017930	ENSXMAP00000035566	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.758
DUSP3	LOC102237032	ENSXMAP00000017930	ENSXMAP00000028528	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.945
DUSP3	LOC102237237	ENSXMAP00000017930	ENSXMAP00000024361	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.758
DUSP3	mapk1	ENSXMAP00000017930	ENSXMAP00000006468	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.945
DUSP3	mapk10	ENSXMAP00000017930	ENSXMAP00000004516	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.758
DUSP3	mapk7	ENSXMAP00000017930	ENSXMAP00000013808	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.476
DUSP3	mapk8	ENSXMAP00000017930	ENSXMAP00000034641	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase.	0.758
DUSP3	vrk3	ENSXMAP00000017930	ENSXMAP00000014252	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	VRK serine/threonine kinase 3.	0.550
ENSXMAP00000023172	LOC102218102	ENSXMAP00000023172	ENSXMAP00000010371	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.583
ENSXMAP00000023172	LOC102223022	ENSXMAP00000023172	ENSXMAP00000041213	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	V-fos FBJ murine osteosarcoma viral oncogene homolog Aa.	0.951
ENSXMAP00000023172	LOC102223674	ENSXMAP00000023172	ENSXMAP00000010282	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.583
ENSXMAP00000023172	LOC102224057	ENSXMAP00000023172	ENSXMAP00000004024	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	V-fos FBJ murine osteosarcoma viral oncogene homolog Ab.	0.989
ENSXMAP00000023172	LOC102231047	ENSXMAP00000023172	ENSXMAP00000021619	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.583
ENSXMAP00000023172	LOC102233752	ENSXMAP00000023172	ENSXMAP00000034299	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.583
ENSXMAP00000023172	LOC102234094	ENSXMAP00000023172	ENSXMAP00000035566	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Mitogen-activated protein kinase.	0.855