48 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ppp2r5b	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (522 aa)
	LOC102227689	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
	lrp4	Low density lipoprotein receptor-related protein 4. (1836 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	lrp6	Low density lipoprotein receptor-related protein 6. (1610 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (423 aa)
	zisupton	Uncharacterized protein. (1379 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
	ppp2r5c	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (525 aa)
	LOC102229857	Si:ch211-93g23.2. (273 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	hmgxb3	HMG box domain containing 3. (1265 aa)
	LOC102223777	Serine/threonine-protein phosphatase. (309 aa)
	LOC102228256	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	LOC102216940	Uncharacterized protein. (603 aa)
	dvl2	Dishevelled segment polarity protein 2. (763 aa)
	LOC102236245	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (433 aa)
	ppp2r5a	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (515 aa)
	LOC102233479	Dishevelled segment polarity protein 3a. (686 aa)
	Fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
	LOC102237243	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
	axin1	Axin 1. (850 aa)
	ppp2r5e	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (478 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	gsk3a	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC102222565	APC membrane recruitment protein 1. (955 aa)
	ENSXMAP00000026472	DIX domain-containing protein. (55 aa)
	LOC102217180	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (579 aa)
	ENSXMAP00000029934	Protein phosphatase 2, regulatory subunit B', delta. (259 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	dvl1	Dishevelled segment polarity protein 1a. (720 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2527 aa)
	ENSXMAP00000033237	Glycogen synthase kinase binding protein. (142 aa)
	LOC102232349	Zgc:162396. (272 aa)
	wnt1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	ENSXMAP00000035407	FZ domain-containing protein. (199 aa)
	LOC102238120	Uncharacterized protein. (917 aa)
	lrp5	Low density lipoprotein receptor-related protein 5. (1649 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	LOC102228510	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
	csnk1a1	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (353 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC102228925	Uncharacterized protein. (881 aa)
	Ppp2r5d	Uncharacterized protein. (196 aa)
	wnt8b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
	ENSXMAP00000041150	APC_N_CC domain-containing protein. (426 aa)
	LOC102232095	Zgc:162780. (280 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000026472	ENSXMAP00000035407	ENSXMAP00000026472	ENSXMAP00000035407	DIX domain-containing protein.	FZ domain-containing protein.	0.536
ENSXMAP00000026472	ENSXMAP00000041150	ENSXMAP00000026472	ENSXMAP00000041150	DIX domain-containing protein.	APC_N_CC domain-containing protein.	0.534
ENSXMAP00000026472	Fzd8	ENSXMAP00000026472	ENSXMAP00000019636	DIX domain-containing protein.	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.480
ENSXMAP00000026472	LOC102227689	ENSXMAP00000026472	ENSXMAP00000001349	DIX domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.480
ENSXMAP00000026472	LOC102228256	ENSXMAP00000026472	ENSXMAP00000010484	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.508
ENSXMAP00000026472	LOC102228510	ENSXMAP00000026472	ENSXMAP00000037867	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.508
ENSXMAP00000026472	LOC102228925	ENSXMAP00000026472	ENSXMAP00000039602	DIX domain-containing protein.	Uncharacterized protein.	0.696
ENSXMAP00000026472	LOC102236245	ENSXMAP00000026472	ENSXMAP00000016621	DIX domain-containing protein.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.535
ENSXMAP00000026472	LOC102237243	ENSXMAP00000026472	ENSXMAP00000020391	DIX domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.480
ENSXMAP00000026472	LOC102238120	ENSXMAP00000026472	ENSXMAP00000036695	DIX domain-containing protein.	Uncharacterized protein.	0.536
ENSXMAP00000026472	apc2	ENSXMAP00000026472	ENSXMAP00000032932	DIX domain-containing protein.	APC regulator of WNT signaling pathway 2.	0.534
ENSXMAP00000026472	axin1	ENSXMAP00000026472	ENSXMAP00000020486	DIX domain-containing protein.	Axin 1.	0.696
ENSXMAP00000026472	csnk1a1	ENSXMAP00000026472	ENSXMAP00000037915	DIX domain-containing protein.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.570
ENSXMAP00000026472	ctnnb1	ENSXMAP00000026472	ENSXMAP00000037480	DIX domain-containing protein.	Catenin (cadherin-associated protein), beta 1.	0.625
ENSXMAP00000026472	gsk3a	ENSXMAP00000026472	ENSXMAP00000026075	DIX domain-containing protein.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.535
ENSXMAP00000026472	gsk3b	ENSXMAP00000026472	ENSXMAP00000004053	DIX domain-containing protein.	Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.	0.535
ENSXMAP00000026472	lrp5	ENSXMAP00000026472	ENSXMAP00000037096	DIX domain-containing protein.	Low density lipoprotein receptor-related protein 5.	0.524
ENSXMAP00000026472	lrp6	ENSXMAP00000026472	ENSXMAP00000002816	DIX domain-containing protein.	Low density lipoprotein receptor-related protein 6.	0.524
ENSXMAP00000026472	wnt1	ENSXMAP00000026472	ENSXMAP00000035020	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.576
ENSXMAP00000026472	wnt3a	ENSXMAP00000026472	ENSXMAP00000005800	DIX domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.497