STRINGSTRING
ENSXMAP00000023013 ENSXMAP00000023013 ENSXMAP00000041243 ENSXMAP00000041243 ENSXMAP00000041023 ENSXMAP00000041023 ENSXMAP00000040541 ENSXMAP00000040541 ENSXMAP00000040449 ENSXMAP00000040449 ENSXMAP00000039989 ENSXMAP00000039989 LOC102222917 LOC102222917 rad50 rad50 ENSXMAP00000039044 ENSXMAP00000039044 ENSXMAP00000038955 ENSXMAP00000038955 ENSXMAP00000038433 ENSXMAP00000038433 Xrcc4 Xrcc4 ENSXMAP00000037293 ENSXMAP00000037293 ENSXMAP00000037127 ENSXMAP00000037127 ENSXMAP00000037091 ENSXMAP00000037091 ENSXMAP00000036662 ENSXMAP00000036662 dntt dntt ENSXMAP00000036529 ENSXMAP00000036529 ENSXMAP00000036123 ENSXMAP00000036123 ENSXMAP00000035028 ENSXMAP00000035028 ENSXMAP00000033462 ENSXMAP00000033462 tdp1 tdp1 xrcc6 xrcc6 LOC102231167 LOC102231167 ENSXMAP00000032554 ENSXMAP00000032554 ENSXMAP00000032360 ENSXMAP00000032360 ENSXMAP00000031861 ENSXMAP00000031861 ENSXMAP00000031118 ENSXMAP00000031118 ENSXMAP00000030905 ENSXMAP00000030905 pias4 pias4 ENSXMAP00000029359 ENSXMAP00000029359 ENSXMAP00000029079 ENSXMAP00000029079 ENSXMAP00000029005 ENSXMAP00000029005 ankrd11 ankrd11 ENSXMAP00000027743 ENSXMAP00000027743 kat5 kat5 tdp2 tdp2 ube2n ube2n ENSXMAP00000026730 ENSXMAP00000026730 ENSXMAP00000026594 ENSXMAP00000026594 ENSXMAP00000025747 ENSXMAP00000025747 ENSXMAP00000025675 ENSXMAP00000025675 ENSXMAP00000025658 ENSXMAP00000025658 LOC102217251 LOC102217251 ENSXMAP00000024331 ENSXMAP00000024331 ENSXMAP00000023263 ENSXMAP00000023263 dclre1c dclre1c ENSXMAP00000021844 ENSXMAP00000021844 ENSXMAP00000021343 ENSXMAP00000021343 ENSXMAP00000021087 ENSXMAP00000021087 poll poll ENSXMAP00000020862 ENSXMAP00000020862 HIST1H2BA HIST1H2BA LOC102223183 LOC102223183 LOC102222618 LOC102222618 Ube2v2 Ube2v2 LOC102235067 LOC102235067 tp53bp1 tp53bp1 rnf8 rnf8 atm atm LOC102226689 LOC102226689 xrcc5 xrcc5 lig4 lig4 paxip1 paxip1 LOC102223059 LOC102223059 tmem182 tmem182 mdc1 mdc1 nhej1 nhej1 M4A7C9_XIPMA M4A7C9_XIPMA M4A7C6_XIPMA M4A7C6_XIPMA brca1 brca1 Nsd2 Nsd2 nbn nbn LOC102225258 LOC102225258 mre11 mre11 cnppd1 cnppd1 prkdc prkdc polm polm rif1 rif1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSXMAP00000023013Histone H2B; Belongs to the histone H2B family. (156 aa)
ENSXMAP00000041243Histone H2B; Belongs to the histone H2B family. (111 aa)
ENSXMAP00000041023Reverse transcriptase domain-containing protein. (1125 aa)
ENSXMAP00000040541Reverse transcriptase domain-containing protein. (262 aa)
ENSXMAP00000040449Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
ENSXMAP00000039989Reverse transcriptase domain-containing protein. (1275 aa)
LOC102222917Endo/exonuclease/phosphatase domain-containing protein. (345 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
ENSXMAP00000039044Reverse transcriptase domain-containing protein. (866 aa)
ENSXMAP00000038955Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (145 aa)
ENSXMAP00000038433Zgc:171759; Belongs to the histone H2B family. (130 aa)
Xrcc4Uncharacterized protein. (296 aa)
ENSXMAP00000037293Reverse transcriptase domain-containing protein. (1238 aa)
ENSXMAP00000037127Reverse transcriptase domain-containing protein. (930 aa)
ENSXMAP00000037091Reverse transcriptase domain-containing protein. (1291 aa)
ENSXMAP00000036662Reverse transcriptase domain-containing protein. (971 aa)
dnttDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (497 aa)
ENSXMAP00000036529Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSXMAP00000036123Histone H2B; Belongs to the histone H2B family. (111 aa)
ENSXMAP00000035028Reverse transcriptase domain-containing protein. (852 aa)
ENSXMAP00000033462Histone H2B; Belongs to the histone H2B family. (158 aa)
tdp1Tyrosyl-DNA phosphodiesterase 1. (620 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (610 aa)
LOC102231167Transmembrane protein 182b. (244 aa)
ENSXMAP00000032554Histone H2B; Belongs to the histone H2B family. (112 aa)
ENSXMAP00000032360Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (158 aa)
ENSXMAP00000031861Reverse transcriptase domain-containing protein. (1319 aa)
ENSXMAP00000031118PWWP domain-containing protein. (158 aa)
ENSXMAP00000030905Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
ENSXMAP00000029359Histone H2B; Belongs to the histone H2B family. (115 aa)
ENSXMAP00000029079annotation not available (95 aa)
ENSXMAP00000029005Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)
ankrd11Ankyrin repeat domain 11. (2826 aa)
ENSXMAP00000027743Reverse transcriptase domain-containing protein. (1187 aa)
kat5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (560 aa)
tdp2Tyrosyl-DNA phosphodiesterase 2b. (359 aa)
ube2nUbiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
ENSXMAP00000026730Histone H2B; Belongs to the histone H2B family. (150 aa)
ENSXMAP00000026594Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
ENSXMAP00000025747Histone H2B; Belongs to the histone H2B family. (120 aa)
ENSXMAP00000025675Reverse transcriptase domain-containing protein. (988 aa)
ENSXMAP00000025658Endo/exonuclease/phosphatase domain-containing protein. (477 aa)
LOC102217251Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSXMAP00000024331Histone H2B; Belongs to the histone H2B family. (111 aa)
ENSXMAP00000023263Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (93 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (578 aa)
ENSXMAP00000021844Reverse transcriptase domain-containing protein. (1319 aa)
ENSXMAP00000021343Reverse transcriptase domain-containing protein. (1291 aa)
ENSXMAP00000021087Reverse transcriptase domain-containing protein. (832 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (599 aa)
ENSXMAP00000020862Uncharacterized protein; Belongs to the histone H2A family. (245 aa)
HIST1H2BAHistone H2B; Belongs to the histone H2B family. (116 aa)
LOC102223183Histone H2B; Belongs to the histone H2B family. (124 aa)
LOC102222618Histone H2A; Belongs to the histone H2A family. (138 aa)
Ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (181 aa)
LOC102235067Histone H2B; Belongs to the histone H2B family. (122 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1252 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (473 aa)
atmATM serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2875 aa)
LOC102226689X-ray repair complementing defective repair in Chinese hamster cells 4. (338 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (722 aa)
lig4DNA ligase. (909 aa)
paxip1PAX interacting (with transcription-activation domain) protein 1. (1068 aa)
LOC102223059Uncharacterized protein. (250 aa)
tmem182Transmembrane protein 182a. (246 aa)
mdc1Uncharacterized protein. (2106 aa)
nhej1Nonhomologous end-joining factor 1. (305 aa)
M4A7C9_XIPMAHistone H2B; Belongs to the histone H2B family. (134 aa)
M4A7C6_XIPMAHistone H2B; Belongs to the histone H2B family. (128 aa)
brca1Uncharacterized protein. (1370 aa)
Nsd2Nuclear receptor binding SET domain protein 2. (464 aa)
nbnNibrin. (831 aa)
LOC102225258UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (743 aa)
cnppd1Cyclin Pas1/PHO80 domain containing 1. (430 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4072 aa)
polmDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (502 aa)
rif1Replication timing regulatory factor 1. (2191 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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