(53 nodes) Glycolysis network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	bpgm	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (279 aa)
	LOC102223990	Triosephosphate isomerase. (247 aa)
	LOC102225387	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (516 aa)
	LOC102229411	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	eno1	Enolase 1a, (alpha). (432 aa)
	LOC102226750	Hexokinase 2. (916 aa)
	LOC102216735	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (793 aa)
	LOC102237407	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	LOC102232942	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	LOC102234000	Glyceraldehyde-3-phosphate dehydrogenase. (335 aa)
	LOC102232711	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (787 aa)
	LOC102227534	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	tpi1	Triosephosphate isomerase. (296 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (333 aa)
	LOC102236105	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	adpgk	ADP-dependent glucokinase. (494 aa)
	LOC102227865	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	LOC102225230	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	LOC102222010	Hexokinase domain containing 1. (934 aa)
	LOC102232621	ADP-dependent glucokinase 2. (493 aa)
	LOC102220680	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	pdxp	Pyridoxal (pyridoxine, vitamin B6) phosphatase; Belongs to the HAD-like hydrolase superfamily. (315 aa)
	LOC102232138	Pyruvate kinase; Belongs to the pyruvate kinase family. (538 aa)
	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (529 aa)
	LOC102229255	Enolase 1b, (alpha). (434 aa)
	LOC102217518	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b. (537 aa)
	pgk1	Phosphoglycerate kinase. (400 aa)
	LOC102225638	Pyruvate kinase; Belongs to the pyruvate kinase family. (554 aa)
	gckr	Uncharacterized protein. (599 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	LOC102219400	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (293 aa)
	LOC102232392	Phosphotransferase. (491 aa)
	LOC102223392	Enolase 2. (434 aa)
	ENSXMAP00000024626	Uncharacterized protein. (312 aa)
	eno3	Enolase 3, (beta, muscle). (434 aa)
	LOC102230006	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b. (477 aa)
	pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (524 aa)
	eno2	Uncharacterized protein. (434 aa)
	gck	Phosphotransferase. (478 aa)
	LOC102227832	Uncharacterized protein. (923 aa)
	LOC102219543	Pyruvate kinase; Belongs to the pyruvate kinase family. (557 aa)
	fam126b	Zgc:158316. (638 aa)
	LOC102220922	Glucosamine-6-phosphate isomerase. (275 aa)
	LOC102231764	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (835 aa)
	LOC102222621	Glyceraldehyde-3-phosphate dehydrogenase. (334 aa)
	eno4	Enolase 4. (603 aa)
	LOC102228980	Hexokinase 1. (931 aa)
	mycbpap	Uncharacterized protein. (653 aa)
	LOC102217219	Si:dkey-96f10.1. (470 aa)
	LOC102224342	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (871 aa)
	LOC102227514	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a. (505 aa)
	gnpda2	Glucosamine-6-phosphate isomerase. (277 aa)
	pgp	Phosphoglycolate phosphatase; Belongs to the HAD-like hydrolase superfamily. (312 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102216735	LOC102217219	ENSXMAP00000006499	ENSXMAP00000035318	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Si:dkey-96f10.1.	0.778
LOC102216735	LOC102217518	ENSXMAP00000006499	ENSXMAP00000017790	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b.	0.778
LOC102216735	LOC102219400	ENSXMAP00000006499	ENSXMAP00000022744	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.572
LOC102216735	LOC102219543	ENSXMAP00000006499	ENSXMAP00000029823	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.702
LOC102216735	LOC102220680	ENSXMAP00000006499	ENSXMAP00000015722	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	0.914
LOC102216735	LOC102220922	ENSXMAP00000006499	ENSXMAP00000030227	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Glucosamine-6-phosphate isomerase.	0.434
LOC102216735	LOC102222010	ENSXMAP00000006499	ENSXMAP00000014578	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Hexokinase domain containing 1.	0.847
LOC102216735	LOC102222621	ENSXMAP00000006499	ENSXMAP00000001007	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.530
LOC102216735	LOC102223392	ENSXMAP00000006499	ENSXMAP00000023105	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Enolase 2.	0.596
LOC102216735	LOC102223990	ENSXMAP00000006499	ENSXMAP00000001175	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Triosephosphate isomerase.	0.824
LOC102216735	LOC102225230	ENSXMAP00000006499	ENSXMAP00000013819	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.948
LOC102216735	LOC102225387	ENSXMAP00000006499	ENSXMAP00000001308	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	0.778
LOC102216735	LOC102225638	ENSXMAP00000006499	ENSXMAP00000021177	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Pyruvate kinase; Belongs to the pyruvate kinase family.	0.738
LOC102216735	LOC102226750	ENSXMAP00000006499	ENSXMAP00000004833	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Hexokinase 2.	0.830
LOC102216735	LOC102227514	ENSXMAP00000006499	ENSXMAP00000035933	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a.	0.778
LOC102216735	LOC102227534	ENSXMAP00000006499	ENSXMAP00000010791	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.948
LOC102216735	LOC102227832	ENSXMAP00000006499	ENSXMAP00000029420	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Uncharacterized protein.	0.830
LOC102216735	LOC102227865	ENSXMAP00000006499	ENSXMAP00000012733	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.532
LOC102216735	LOC102228980	ENSXMAP00000006499	ENSXMAP00000032057	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Hexokinase 1.	0.830
LOC102216735	LOC102229255	ENSXMAP00000006499	ENSXMAP00000017486	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.	Enolase 1b, (alpha).	0.596