127 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	madd	MAP-kinase activating death domain. (1563 aa)
	RAB39B	RAB39B, member RAS oncogene family. (213 aa)
	LOC102230820	RAB38c, member of RAS oncogene family. (260 aa)
	LOC111612265	VPS9 domain-containing protein. (975 aa)
	LOC102219021	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (257 aa)
	M3ZED6_XIPMA	Uncharacterized protein. (857 aa)
	M3ZFP1_XIPMA	SH3 and SYLF domain containing 1. (276 aa)
	trappc4	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (219 aa)
	jph2	Junctophilin 2. (827 aa)
	trappc10	Trafficking protein particle complex 10. (1264 aa)
	rin1	Si:ch211-168d1.3. (787 aa)
	LOC102238002	Unc-51 like autophagy activating kinase 1a. (892 aa)
	dennd4b	DENN/MADD domain containing 4B. (1505 aa)
	mon1a	MON1 secretory trafficking family member A. (521 aa)
	dennd1b	DENN domain containing 1B. (877 aa)
	hps1	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (663 aa)
	hps4	HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (611 aa)
	rab32	RAB32a, member RAS oncogene family. (213 aa)
	LOC102232710	Uncharacterized protein. (218 aa)
	rab8a	RAB8A, member RAS oncogene family. (206 aa)
	LOC102219839	Uncharacterized protein. (1519 aa)
	rab35	RAB35, member RAS oncogene family b. (184 aa)
	LOC102220770	UDENN domain-containing protein. (1095 aa)
	LOC102236184	Zgc:171927. (214 aa)
	dennd2d	DENN/MADD domain containing 2Da. (604 aa)
	sbf1	SET binding factor 1. (1823 aa)
	RSPH1	Radial spoke head component 1. (228 aa)
	rab14	Uncharacterized protein. (215 aa)
	LOC102230523	Uncharacterized protein. (145 aa)
	LOC102231865	Uncharacterized protein. (203 aa)
	ulk2	Unc-51 like autophagy activating kinase 2. (1041 aa)
	jph3	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (786 aa)
	rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (474 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	trappc1	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (135 aa)
	dennd1a	DENN/MADD domain containing 1A. (947 aa)
	RIN2	Ras and Rab interactor 2. (948 aa)
	dennd6a	DENN/MADD domain containing 6Aa. (595 aa)
	als2	Alsin Rho guanine nucleotide exchange factor ALS2 b. (1628 aa)
	dennd2b	Suppression of tumorigenicity 5. (1134 aa)
	ankrd27	Ankyrin repeat domain 27 (VPS9 domain). (1035 aa)
	rab21	RAB21, member RAS oncogene family. (220 aa)
	trappc3	Trafficking protein particle complex subunit; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (180 aa)
	trappc11	Trafficking protein particle complex 11. (1123 aa)
	vps9d1	VPS9 domain containing 1. (659 aa)
	akt2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	LOC102237980	Uncharacterized protein. (223 aa)
	morn3	MORN repeat containing 3. (223 aa)
	LOC102237419	RAB15, member RAS oncogene family. (210 aa)
	LOC102219654	UDENN domain-containing protein. (1127 aa)
	rab3gap1	RAB3 GTPase activating protein subunit 1. (967 aa)
	ccz1	CCZ1 homolog, vacuolar protein trafficking and biogenesis associated. (480 aa)
	rsph10b	Radial spoke head 10 homolog B. (756 aa)
	LOC102234551	Uncharacterized protein. (215 aa)
	gripap1	GRIP1 associated protein 1. (879 aa)
	dennd6b	DENN/MADD domain containing 6B. (570 aa)
	dennd3	DENN/MADD domain containing 3a. (1263 aa)
	LOC102218920	Uncharacterized protein. (202 aa)
	rab13	Uncharacterized protein. (200 aa)
	LOC102224645	MON1 secretory trafficking family member Bb. (609 aa)
	LOC102230474	RAB38b, member of RAS oncogene family. (218 aa)
	armc5	Armadillo repeat containing 5. (1132 aa)
	LOC102230863	Uncharacterized protein. (189 aa)
	LOC102224939	RAB5B, member RAS oncogene family. (216 aa)
	LOC102219512	Trafficking protein particle complex 6b-like. (163 aa)
	LOC102237454	RAB guanine nucleotide exchange factor (GEF) 1, like. (510 aa)
	rab3gap2	RAB3 GTPase activating protein subunit 2 (non-catalytic). (1373 aa)
	wdr54	WD repeat domain 54. (336 aa)
	M4AYK1_XIPMA	RAB9B, member RAS oncogene family. (206 aa)
	ENSXMAP00000020639	Uncharacterized protein. (111 aa)
	ENSXMAP00000020860	RAB3A interacting protein (rabin3)-like 1. (168 aa)
	trappc13	Trafficking protein particle complex 13. (417 aa)
	morn4	MORN repeat containing 4. (146 aa)
	trappc8	Trafficking protein particle complex 8. (1451 aa)
	dennd5a	DENN/MADD domain containing 5A. (1289 aa)
	LOC102232639	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (442 aa)
	LOC102219790	RAB7a, member RAS oncogene family. (207 aa)
	LOC102230669	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (447 aa)
	garem1	GRB2 associated, regulator of MAPK1. (869 aa)
	morn5	MORN repeat containing 5. (178 aa)
	rab8b	Multiple EGF-like-domains 8. (207 aa)
	rab18	RAB18A, member RAS oncogene family. (204 aa)
	dennd4a	DENN/MADD domain containing 4A. (1685 aa)
	LOC102220727	RAB42, member RAS oncogene family a. (218 aa)
	LOC102227378	RAB18B, member RAS oncogene family. (205 aa)
	rab12	RAB12, member RAS oncogene family. (244 aa)
	rab5c	RAB5C, member RAS oncogene family. (220 aa)
	trappc9	Trafficking protein particle complex 9. (996 aa)
	LOC102225655	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (447 aa)
	LOC111611895	Uncharacterized protein. (787 aa)
	LOC102236001	Ras and Rab interactor 2. (1085 aa)
	LOC102221304	Lebercilin LCA5. (806 aa)
	LOC102228872	Si:dkey-34d22.5. (222 aa)
	gapvd1	GTPase activating protein and VPS9 domains 1. (1485 aa)
	LOC102221989	RAB5A, member RAS oncogene family, a. (216 aa)
	rab3a	RAB3A, member RAS oncogene family, b. (219 aa)
	DENND4A	DENN domain containing 4A. (1970 aa)
	ulk1	Unc-51 like autophagy activating kinase 1. (1064 aa)
	LOC102232504	Non-specific serine/threonine protein kinase. (503 aa)
	LOC102221052	CHM Rab escort protein. (697 aa)
	rab3ip	RAB3A interacting protein (rabin3). (440 aa)
	LOC102228070	Zgc:162171. (227 aa)
	TRAPPC5	Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi. (188 aa)
	LOC102226755	Si:dkey-16l2.16. (209 aa)
	LOC102231109	Uncharacterized protein. (223 aa)
	LOC102230535	Uncharacterized protein. (207 aa)
	trappc2	Trafficking protein particle complex 2. (140 aa)
	LOC102220700	Si:ch211-146m13.3. (857 aa)
	dennd4c	DENN/MADD domain containing 4C. (1910 aa)
	LOC102237954	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	sbf2	SET binding factor 2. (1901 aa)
	rab10	RAB10, member RAS oncogene family. (208 aa)
	LOC102233132	RAB5A, member RAS oncogene family, b. (216 aa)
	ENSXMAP00000037633	SH2 domain-containing protein. (134 aa)
	trappc12	Trafficking protein particle complex 12. (814 aa)
	LOC102236931	ZRAB1B, member RAS oncogene family a. (201 aa)
	jph1	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (693 aa)
	DENND2A	DENN domain containing 2A. (1031 aa)
	LOC102219409	RAB8A, member RAS oncogene family. (206 aa)
	rab27a	RAB27A, member RAS oncogene family. (220 aa)
	RAB38	RAB38, member RAS oncogene family. (238 aa)
	LOC102236167	Si:dkey-76b14.2. (915 aa)
	LOC102224444	DENN/MADD domain containing 5B. (1270 aa)
	LOC102236163	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
	dennd2c	DENN/MADD domain containing 2C. (921 aa)
	LOC102229808	RAB27B, member RAS oncogene family. (218 aa)
	trappc2l	Trafficking protein particle complex 2-like. (143 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND2A	LOC102221052	ENSXMAP00000038554	ENSXMAP00000029837	DENN domain containing 2A.	CHM Rab escort protein.	0.469
DENND2A	LOC102226755	ENSXMAP00000038554	ENSXMAP00000032280	DENN domain containing 2A.	Si:dkey-16l2.16.	0.689
DENND2A	rab35	ENSXMAP00000038554	ENSXMAP00000004030	DENN domain containing 2A.	RAB35, member RAS oncogene family b.	0.689
ENSXMAP00000020639	LOC102218920	ENSXMAP00000020639	ENSXMAP00000015808	Uncharacterized protein.	Uncharacterized protein.	0.808
ENSXMAP00000020639	LOC102219512	ENSXMAP00000020639	ENSXMAP00000018237	Uncharacterized protein.	Trafficking protein particle complex 6b-like.	0.974
ENSXMAP00000020639	LOC102221304	ENSXMAP00000020639	ENSXMAP00000027278	Uncharacterized protein.	Lebercilin LCA5.	0.951
ENSXMAP00000020639	LOC102225655	ENSXMAP00000020639	ENSXMAP00000027133	Uncharacterized protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.482
ENSXMAP00000020639	LOC102230669	ENSXMAP00000020639	ENSXMAP00000023085	Uncharacterized protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.482
ENSXMAP00000020639	LOC102231865	ENSXMAP00000020639	ENSXMAP00000005770	Uncharacterized protein.	Uncharacterized protein.	0.808
ENSXMAP00000020639	LOC102232639	ENSXMAP00000020639	ENSXMAP00000022139	Uncharacterized protein.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.482
ENSXMAP00000020639	LOC102236184	ENSXMAP00000020639	ENSXMAP00000004695	Uncharacterized protein.	Zgc:171927.	0.808
ENSXMAP00000020639	LOC102236931	ENSXMAP00000020639	ENSXMAP00000037874	Uncharacterized protein.	ZRAB1B, member RAS oncogene family a.	0.808
ENSXMAP00000020639	TRAPPC5	ENSXMAP00000020639	ENSXMAP00000031728	Uncharacterized protein.	Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.	0.401
ENSXMAP00000020639	trappc1	ENSXMAP00000020639	ENSXMAP00000007392	Uncharacterized protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.984
ENSXMAP00000020639	trappc10	ENSXMAP00000020639	ENSXMAP00000001282	Uncharacterized protein.	Trafficking protein particle complex 10.	0.982
ENSXMAP00000020639	trappc11	ENSXMAP00000020639	ENSXMAP00000011033	Uncharacterized protein.	Trafficking protein particle complex 11.	0.963
ENSXMAP00000020639	trappc12	ENSXMAP00000020639	ENSXMAP00000037739	Uncharacterized protein.	Trafficking protein particle complex 12.	0.901
ENSXMAP00000020639	trappc13	ENSXMAP00000020639	ENSXMAP00000020984	Uncharacterized protein.	Trafficking protein particle complex 13.	0.870
ENSXMAP00000020639	trappc2	ENSXMAP00000020639	ENSXMAP00000034229	Uncharacterized protein.	Trafficking protein particle complex 2.	0.974
ENSXMAP00000020639	trappc2l	ENSXMAP00000020639	ENSXMAP00000041218	Uncharacterized protein.	Trafficking protein particle complex 2-like.	0.976