STRINGSTRING
LOC102217142 LOC102217142 LOC102218819 LOC102218819 LOC102225266 LOC102225266 SHC4 SHC4 M3ZJA3_XIPMA M3ZJA3_XIPMA LOC102236577 LOC102236577 LOC102221502 LOC102221502 gng7 gng7 esr1 esr1 foxo3 foxo3 LOC102225882 LOC102225882 LOC102230034 LOC102230034 PRMT8 PRMT8 LOC102233053 LOC102233053 LOC102225341 LOC102225341 STRN STRN GNG4 GNG4 akt1 akt1 gnb5 gnb5 LOC102218115 LOC102218115 LOC102218377 LOC102218377 zdhhc21 zdhhc21 LOC102218230 LOC102218230 strn3 strn3 LOC102235773 LOC102235773 LOC102236744 LOC102236744 LOC102232343 LOC102232343 LOC102226637 LOC102226637 LOC102235525 LOC102235525 LOC102232995 LOC102232995 LOC102225716 LOC102225716 LOC102220072 LOC102220072 SPHK1 SPHK1 akt2 akt2 gng10 gng10 LOC102216436 LOC102216436 LOC102218551 LOC102218551 gng2 gng2 LOC102235425 LOC102235425 uhmk1 uhmk1 LOC102219207 LOC102219207 LOC102223913 LOC102223913 LOC102220588 LOC102220588 zdhhc7 zdhhc7 LOC102224365 LOC102224365 GNG5 GNG5 LOC102225297 LOC102225297 pik3r1 pik3r1 pdpk1 pdpk1 gnb1 gnb1 LOC102226157 LOC102226157 CSDE1 CSDE1 LOC102226671 LOC102226671 LOC102236489 LOC102236489 LOC102218679-2 LOC102218679-2 LOC102227659 LOC102227659 pik3r3 pik3r3 LOC111611086 LOC111611086 LOC102223235 LOC102223235 LOC102221737 LOC102221737 hras hras LOC102221770 LOC102221770 SRC SRC LOC102222110 LOC102222110 cav1 cav1 LOC102225341-2 LOC102225341-2 ENSXMAP00000026312 ENSXMAP00000026312 LOC102223147 LOC102223147 shc1 shc1 LOC102228806 LOC102228806 GNB4 GNB4 LOC102222625 LOC102222625 gnb3 gnb3 LOC102232504 LOC102232504 LOC102232037 LOC102232037 SPHK1-2 SPHK1-2 LOC102227870 LOC102227870 elk1 elk1 KRAS KRAS LOC102221045 LOC102221045 cav2 cav2 ENSXMAP00000034655 ENSXMAP00000034655 LOC102218202 LOC102218202 LOC102230695 LOC102230695 LOC102237954 LOC102237954 LOC102216981 LOC102216981 LOC102227197 LOC102227197 LOC102218539 LOC102218539 LOC102233436 LOC102233436 LOC102219229 LOC102219229 LOC102232628 LOC102232628 LOC102220768 LOC102220768 cav3 cav3 LOC102231022 LOC102231022 LOC102235279 LOC102235279 creb1 creb1 LOC102238393 LOC102238393 strn4 strn4 prkcz prkcz hspb1 hspb1 gng3 gng3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102217142Sphingosine-1-phosphate receptor 3a; Belongs to the G-protein coupled receptor 1 family. (396 aa)
LOC102218819Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (199 aa)
LOC102225266Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
SHC4SHC adaptor protein 4. (538 aa)
M3ZJA3_XIPMAEpidermal growth factor. (946 aa)
LOC102236577Uncharacterized protein. (408 aa)
LOC102221502Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
gng7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
esr1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (612 aa)
foxo3Forkhead protein FoxO5. (664 aa)
LOC102225882Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102230034Uncharacterized protein. (354 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (454 aa)
LOC102233053Exportin 1 (CRM1 homolog, yeast) a. (1066 aa)
LOC102225341cAMP responsive element modulator a. (111 aa)
STRNStriatin. (779 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (224 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
gnb5Guanine nucleotide binding protein (G protein), beta 5a. (361 aa)
LOC102218115Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
LOC102218377Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
zdhhc21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
LOC102218230Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
strn3Striatin, calmodulin binding protein 3. (704 aa)
LOC102235773Cyclin-dependent kinase inhibitor 1Bb. (194 aa)
LOC102236744Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
LOC102232343Epithelial mitogen homolog (mouse). (164 aa)
LOC102226637EGF-like domain-containing protein. (153 aa)
LOC102235525Protein arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (348 aa)
LOC102232995Zgc:55558. (187 aa)
LOC102225716Guanine nucleotide binding protein (G protein), beta polypeptide 2. (340 aa)
LOC102220072Uncharacterized protein. (376 aa)
SPHK1Sphingosine kinase 1. (564 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC102216436Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (728 aa)
LOC102218551ZP domain-containing protein. (512 aa)
gng2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
LOC102235425Uncharacterized protein. (726 aa)
uhmk1U2AF homology motif (UHM) kinase 1. (437 aa)
LOC102219207Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (188 aa)
LOC102223913Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (193 aa)
LOC102220588Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
zdhhc7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (320 aa)
LOC102224365Striatin, calmodulin binding protein. (780 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
LOC102225297Guanine nucleotide binding protein (G protein), beta 5b. (395 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
gnb1Guanine nucleotide binding protein (G protein), beta polypeptide 1a. (340 aa)
LOC102226157Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1152 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (907 aa)
LOC102226671Protein arginine methyltransferase 8b; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (405 aa)
LOC102236489Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2. (350 aa)
LOC102218679-2Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b. (355 aa)
LOC102227659Uncharacterized protein. (354 aa)
pik3r3Uncharacterized protein. (473 aa)
LOC111611086ZP domain-containing protein. (305 aa)
LOC102223235Uncharacterized protein. (354 aa)
LOC102221737cAMP responsive element binding protein 1. (317 aa)
hrasHRas proto-oncogene, GTPase a. (211 aa)
LOC102221770Estrogen receptor 2b. (668 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC102222110Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
LOC102225341-2KID domain-containing protein. (223 aa)
ENSXMAP00000026312ZP domain-containing protein. (365 aa)
LOC102223147Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b. (382 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (456 aa)
LOC102228806Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
GNB4G protein subunit beta 4. (345 aa)
LOC102222625Guanine nucleotide binding protein (G protein) alpha v1. (361 aa)
gnb3Guanine nucleotide binding protein (G protein), beta polypeptide 3a. (365 aa)
LOC102232504Non-specific serine/threonine protein kinase. (503 aa)
LOC102232037Estrogen receptor 2a. (579 aa)
SPHK1-2Sphingosine kinase 1. (548 aa)
LOC102227870Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
elk1ETS transcription factor ELK1. (527 aa)
KRASV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC102221045Tyrosine-protein kinase receptor. (1416 aa)
cav2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ENSXMAP00000034655ZP domain-containing protein. (377 aa)
LOC102218202Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
LOC102230695Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC102237954Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC102216981Exportin 1 (CRM1 homolog, yeast) b. (1071 aa)
LOC102227197Tyrosine-protein kinase. (542 aa)
LOC102218539Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
LOC102233436Uncharacterized protein. (466 aa)
LOC102219229Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (100 aa)
LOC102232628Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
LOC102220768Guanine nucleotide binding protein (G protein), beta polypeptide 1b. (340 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
LOC102231022Guanine nucleotide binding protein (G protein), gamma 13a. (67 aa)
LOC102235279Tyrosine-protein kinase receptor. (1386 aa)
creb1Uncharacterized protein. (351 aa)
LOC102238393Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
strn4Striatin, calmodulin binding protein 4. (772 aa)
prkczProtein kinase C. (564 aa)
hspb1Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (202 aa)
gng3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.