44 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAK3	Non-specific serine/threonine protein kinase. (574 aa)
	dbt	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (508 aa)
	LOC102223926	Non-specific serine/threonine protein kinase. (610 aa)
	ralgapa1	Ral GTPase activating protein, alpha subunit 1 (catalytic). (2029 aa)
	rock2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
	LOC102226138	Nipsnap homolog 2. (327 aa)
	osbpl11	Oxysterol-binding protein; Belongs to the OSBP family. (715 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	NIPSNAP2	NIPSNAP domain-containing protein. (276 aa)
	wdr11	WD repeat domain 11. (1240 aa)
	pak6	Non-specific serine/threonine protein kinase. (696 aa)
	fam91a1	Family with sequence similarity 91 member A1. (832 aa)
	VANGL1	Vang-like protein. (531 aa)
	nipsnap1	Nipsnap homolog 1 (C. elegans). (278 aa)
	rock1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1380 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (748 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	tmem59	Transmembrane protein 59. (325 aa)
	uaca	Uveal autoantigen with coiled-coil domains and ankyrin repeats b. (1352 aa)
	pak5	Non-specific serine/threonine protein kinase. (782 aa)
	LOC102219024	Tyrosine-protein kinase. (447 aa)
	LOC102226016	Junction plakoglobin a. (721 aa)
	pak1	Non-specific serine/threonine protein kinase. (559 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	slc1a5	Amino acid transporter. (530 aa)
	LOC102222129	Non-specific serine/threonine protein kinase. (507 aa)
	LOC102236845	Tyrosine-protein kinase. (610 aa)
	lamtor1	Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
	LOC102230535	Uncharacterized protein. (207 aa)
	LOC102225392	Non-specific serine/threonine protein kinase. (652 aa)
	ralgapa2	Ral GTPase activating protein, alpha subunit 2 (catalytic). (2048 aa)
	tfrc	Transferrin receptor 1a. (770 aa)
	LOC102235998	Rho GDP dissociation inhibitor (GDI) gamma. (222 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC102219903	Uncharacterized protein. (210 aa)
	LOC102219790	RAB7a, member RAS oncogene family. (207 aa)
	lck	Tyrosine-protein kinase. (500 aa)
	SPATA5	Spermatogenesis associated 5. (900 aa)
	CSK	Tyrosine-protein kinase. (451 aa)
	nsfl1c	NSFL1 (p97) cofactor (p47). (374 aa)
	mtr	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1271 aa)
	LOC102234371	Zgc:136908; Belongs to the AAA ATPase family. (810 aa)
	LOC102217692	Rho GDP dissociation inhibitor (GDI) alpha. (198 aa)
	pak2	Non-specific serine/threonine protein kinase. (526 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	LOC102226016	ENSXMAP00000016789	ENSXMAP00000039861	Tyrosine-protein kinase.	Junction plakoglobin a.	0.441
CSK	LOC102234371	ENSXMAP00000016789	ENSXMAP00000012347	Tyrosine-protein kinase.	Zgc:136908; Belongs to the AAA ATPase family.	0.419
CSK	LOC102236845	ENSXMAP00000016789	ENSXMAP00000033996	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.449
CSK	SPATA5	ENSXMAP00000016789	ENSXMAP00000018399	Tyrosine-protein kinase.	Spermatogenesis associated 5.	0.419
CSK	cav3	ENSXMAP00000016789	ENSXMAP00000038231	Tyrosine-protein kinase.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.487
CSK	dbt	ENSXMAP00000016789	ENSXMAP00000010812	Tyrosine-protein kinase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.418
CSK	lck	ENSXMAP00000016789	ENSXMAP00000019019	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.696
CSK	nsfl1c	ENSXMAP00000016789	ENSXMAP00000016740	Tyrosine-protein kinase.	NSFL1 (p97) cofactor (p47).	0.461
CSK	spata5l1	ENSXMAP00000016789	ENSXMAP00000002301	Tyrosine-protein kinase.	Spermatogenesis associated 5-like 1.	0.419
CSK	tmem59	ENSXMAP00000016789	ENSXMAP00000000459	Tyrosine-protein kinase.	Transmembrane protein 59.	0.435
CSK	uaca	ENSXMAP00000016789	ENSXMAP00000000383	Tyrosine-protein kinase.	Uveal autoantigen with coiled-coil domains and ankyrin repeats b.	0.435
CSK	vcp	ENSXMAP00000016789	ENSXMAP00000007519	Tyrosine-protein kinase.	Valosin containing protein; Belongs to the AAA ATPase family.	0.419
LOC102219024	LOC102226016	ENSXMAP00000040411	ENSXMAP00000039861	Tyrosine-protein kinase.	Junction plakoglobin a.	0.441
LOC102219024	LOC102234371	ENSXMAP00000040411	ENSXMAP00000012347	Tyrosine-protein kinase.	Zgc:136908; Belongs to the AAA ATPase family.	0.419
LOC102219024	LOC102236845	ENSXMAP00000040411	ENSXMAP00000033996	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.449
LOC102219024	SPATA5	ENSXMAP00000040411	ENSXMAP00000018399	Tyrosine-protein kinase.	Spermatogenesis associated 5.	0.419
LOC102219024	cav3	ENSXMAP00000040411	ENSXMAP00000038231	Tyrosine-protein kinase.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.487
LOC102219024	dbt	ENSXMAP00000040411	ENSXMAP00000010812	Tyrosine-protein kinase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.418
LOC102219024	lck	ENSXMAP00000040411	ENSXMAP00000019019	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.697
LOC102219024	nsfl1c	ENSXMAP00000040411	ENSXMAP00000016740	Tyrosine-protein kinase.	NSFL1 (p97) cofactor (p47).	0.461