STRINGSTRING
ankle2 ankle2 VANGL1 VANGL1 dock5 dock5 lman1 lman1 lemd3 lemd3 kalrn kalrn LOC102228072 LOC102228072 iqgap2 iqgap2 LOC102223754 LOC102223754 vrk2 vrk2 letm1 letm1 arhgap21 arhgap21 dock4 dock4 DEPDC1B DEPDC1B M4A4T1_XIPMA M4A4T1_XIPMA M4A4T4_XIPMA M4A4T4_XIPMA arhgap1 arhgap1 LOC102232283 LOC102232283 ykt6 ykt6 tfrc tfrc LOC102219781 LOC102219781 LOC102220041 LOC102220041 LOC102226457 LOC102226457 pak2 pak2 LOC102225731 LOC102225731 LOC102217692 LOC102217692 LOC102233521 LOC102233521 LOC102219831 LOC102219831 LOC102217211 LOC102217211 M4ADK6_XIPMA M4ADK6_XIPMA LOC102233819 LOC102233819 LOC102222464 LOC102222464 itsn1 itsn1 ktn1 ktn1 VAV1 VAV1 LOC102221116 LOC102221116 cyfip1 cyfip1 LOC102222332 LOC102222332 LOC102224638 LOC102224638 LOC102224276 LOC102224276 LOC102229869 LOC102229869 arhgef16 arhgef16 map3k10 map3k10 ndufs3 ndufs3 LOC102226201 LOC102226201 pgrmc2 pgrmc2 ENSXMAP00000022039 ENSXMAP00000022039 elmo2 elmo2 LOC102219790 LOC102219790 LOC102217174 LOC102217174 map3k9 map3k9 prex1 prex1 ENSXMAP00000024129 ENSXMAP00000024129 arhgap5 arhgap5 LOC102225344 LOC102225344 LOC102219903 LOC102219903 elmo1 elmo1 cav1 cav1 mpp3 mpp3 LOC102229025 LOC102229025 LOC102235998 LOC102235998 LOC102230899 LOC102230899 LOC102229675 LOC102229675 VAV3 VAV3 mcf2 mcf2 arhgap35 arhgap35 stbd1 stbd1 DOCK2 DOCK2 dock3 dock3 CDC42 CDC42 LOC102233691 LOC102233691 LOC102225392 LOC102225392 ophn1 ophn1 LOC102230535 LOC102230535 lamtor1 lamtor1 LOC102227542 LOC102227542 stx5 stx5 LOC102226130 LOC102226130 LOC102222129 LOC102222129 mpp7 mpp7 LOC106699750 LOC106699750 PLEKHG3 PLEKHG3 pld1 pld1 letm2 letm2 cav3 cav3 vav2 vav2 LOC102217093 LOC102217093 dock1 dock1 LOC102227975 LOC102227975 kiaa0355 kiaa0355 LOC102217553 LOC102217553 LOC102225458-2 LOC102225458-2 LOC102226251 LOC102226251 ndufa5 ndufa5 arfgap3 arfgap3 ARHGEF26 ARHGEF26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ankle2Ankyrin repeat and LEM domain containing 2. (970 aa)
VANGL1Vang-like protein. (531 aa)
dock5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1799 aa)
lman1Lectin, mannose-binding, 1. (509 aa)
lemd3LEM domain containing 3. (830 aa)
kalrnKalirin RhoGEF kinase a. (2855 aa)
LOC102228072Diaphanous-related formin 3. (1213 aa)
iqgap2IQ motif containing GTPase activating protein 2. (1662 aa)
LOC102223754Ras homolog family member Gb. (191 aa)
vrk2VRK serine/threonine kinase 2. (562 aa)
letm1Leucine zipper-EF-hand containing transmembrane protein 1. (769 aa)
arhgap21Rho GTPase activating protein 21a. (1836 aa)
dock4Dedicator of cytokinesis 4b; Belongs to the DOCK family. (1929 aa)
DEPDC1BDEP domain containing 1B. (532 aa)
M4A4T1_XIPMAUncharacterized protein. (119 aa)
M4A4T4_XIPMARas homolog gene family, member Gd. (101 aa)
arhgap1Uncharacterized protein. (430 aa)
LOC102232283Zgc:92107. (1140 aa)
ykt6YKT6 v-SNARE homolog (S. cerevisiae); Belongs to the synaptobrevin family. (198 aa)
tfrcTransferrin receptor 1a. (770 aa)
LOC102219781Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1154 aa)
LOC102220041Si:ch73-74h11.1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1395 aa)
LOC102226457Rho GTPase activating protein 39. (1040 aa)
pak2Non-specific serine/threonine protein kinase. (526 aa)
LOC102225731Rho GTPase activating protein 35b. (1529 aa)
LOC102217692Rho GDP dissociation inhibitor (GDI) alpha. (198 aa)
LOC102233521Mcf.2 cell line derived transforming sequence-like a. (1180 aa)
LOC102219831Eph receptor A2 b. (991 aa)
LOC102217211Uncharacterized protein. (351 aa)
M4ADK6_XIPMACDC42 effector protein (Rho GTPase binding) 1a. (198 aa)
LOC102233819TNNI3 interacting kinase. (835 aa)
LOC102222464Trio Rho guanine nucleotide exchange factor a. (2882 aa)
itsn1Intersectin 1 (SH3 domain protein). (1557 aa)
ktn1Kinectin 1. (1247 aa)
VAV1Vav guanine nucleotide exchange factor 1. (844 aa)
LOC102221116Uncharacterized protein; Belongs to the DOCK family. (1948 aa)
cyfip1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
LOC102222332Rho GTPase activating protein 21b. (1785 aa)
LOC102224638Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1090 aa)
LOC102224276Membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3); Belongs to the MAGUK family. (604 aa)
LOC102229869RNA binding motif protein 39b. (499 aa)
arhgef16Rho guanine nucleotide exchange factor (GEF) 16. (715 aa)
map3k10Mitogen-activated protein kinase kinase kinase. (1101 aa)
ndufs3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (316 aa)
LOC102226201Eph receptor A2 a. (975 aa)
pgrmc2Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (198 aa)
ENSXMAP00000022039Extended synaptotagmin-like protein 1b. (1008 aa)
elmo2Engulfment and cell motility 2. (721 aa)
LOC102219790RAB7a, member RAS oncogene family. (207 aa)
LOC102217174Mitogen-activated protein kinase kinase kinase. (1021 aa)
map3k9Mitogen-activated protein kinase kinase kinase. (1049 aa)
prex1Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1675 aa)
ENSXMAP00000024129MCF.2 cell line derived transforming sequence-like 2. (1173 aa)
arhgap5Rho GTPase activating protein 5. (1499 aa)
LOC102225344Mcf.2 cell line derived transforming sequence-like b. (1270 aa)
LOC102219903Uncharacterized protein. (210 aa)
elmo1Engulfment and cell motility 1. (740 aa)
cav1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
mpp3Membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3); Belongs to the MAGUK family. (636 aa)
LOC102229025Membrane protein, palmitoylated 7b (MAGUK p55 subfamily member 7); Belongs to the MAGUK family. (524 aa)
LOC102235998Rho GDP dissociation inhibitor (GDI) gamma. (222 aa)
LOC102230899Mitogen-activated protein kinase kinase kinase. (1041 aa)
LOC102229675Vav 3 guanine nucleotide exchange factor b. (862 aa)
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)
mcf2MCF.2 cell line derived transforming sequence a. (1163 aa)
arhgap35Uncharacterized protein. (1552 aa)
stbd1CBM20 domain-containing protein. (884 aa)
DOCK2Dedicator of cytokinesis 2; Belongs to the DOCK family. (1839 aa)
dock3Uncharacterized protein; Belongs to the DOCK family. (2127 aa)
CDC42Cell division cycle 42. (191 aa)
LOC102233691Melanoma cell adhesion molecule a. (618 aa)
LOC102225392Non-specific serine/threonine protein kinase. (652 aa)
ophn1Oligophrenin 1. (801 aa)
LOC102230535Uncharacterized protein. (207 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
LOC102227542VAMP (vesicle-associated membrane protein)-associated protein B and C. (263 aa)
stx5Syntaxin 5A; Belongs to the syntaxin family. (330 aa)
LOC102226130Cell division cycle 42. (191 aa)
LOC102222129Non-specific serine/threonine protein kinase. (507 aa)
mpp7Membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7); Belongs to the MAGUK family. (577 aa)
LOC106699750CDC42 effector protein (Rho GTPase binding) 1b. (348 aa)
PLEKHG3Pleckstrin homology and RhoGEF domain containing G3. (1372 aa)
pld1Phospholipase. (1058 aa)
letm2Leucine zipper-EF-hand containing transmembrane protein 2. (495 aa)
cav3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
vav2Vav 2 guanine nucleotide exchange factor. (880 aa)
LOC102217093Extended synaptotagmin-like protein 1a. (908 aa)
dock1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1873 aa)
LOC102227975Uncharacterized protein. (3143 aa)
kiaa0355Si:ch211-79l17.1. (1087 aa)
LOC102217553Phospholipase. (1031 aa)
LOC102225458-2Heat shock 10 protein 1; Belongs to the GroES chaperonin family. (103 aa)
LOC102226251MCF.2 cell line derived transforming sequence b. (1013 aa)
ndufa5NADH:ubiquinone oxidoreductase subunit A5. (101 aa)
arfgap3ADP-ribosylation factor GTPase activating protein 3. (575 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (962 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: low (16%) [HD]