70 items (Xiphophorus maculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ckap4	Uncharacterized protein. (548 aa)
	arhgap21	Rho GTPase activating protein 21a. (1836 aa)
	DEPDC1B	DEP domain containing 1B. (532 aa)
	fam83b	Family with sequence similarity 83 member B. (917 aa)
	LOC102219781	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1154 aa)
	LOC102220041	Si:ch73-74h11.1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1395 aa)
	LOC102225266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (159 aa)
	sema4c	Uncharacterized protein; Belongs to the semaphorin family. (861 aa)
	rock1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1380 aa)
	VANGL1	Vang-like protein. (531 aa)
	txnl1	Thioredoxin-like 1. (289 aa)
	LOC102225731	Rho GTPase activating protein 35b. (1529 aa)
	LOC102219831	Eph receptor A2 b. (991 aa)
	LOC102217211	Uncharacterized protein. (351 aa)
	ktn1	Kinectin 1. (1247 aa)
	heg1	Heart development protein with EGF-like domains 1. (1128 aa)
	LOC102222332	Rho GTPase activating protein 21b. (1785 aa)
	LOC102224638	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1090 aa)
	LOC102229869	RNA binding motif protein 39b. (499 aa)
	sema4g	Uncharacterized protein; Belongs to the semaphorin family. (844 aa)
	LOC102232428	Microtubule-associated protein. (1115 aa)
	cirbp	Cold inducible RNA binding protein b. (183 aa)
	wdr6	WD repeat domain 6. (1245 aa)
	LOC102226201	Eph receptor A2 a. (975 aa)
	ENSXMAP00000021349	Uncharacterized protein. (155 aa)
	ENSXMAP00000022188	Calponin-homology (CH) domain-containing protein. (116 aa)
	ENSXMAP00000022830	CCDC144C domain-containing protein. (314 aa)
	ENSXMAP00000023342	Uncharacterized protein. (118 aa)
	rbmx	RNA binding motif protein X-linked. (383 aa)
	LOC102216658	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (2014 aa)
	arhgap5	Rho GTPase activating protein 5. (1499 aa)
	PTPN20	Protein tyrosine phosphatase non-receptor type 20. (254 aa)
	LOC102225447	Uncharacterized protein; Belongs to the semaphorin family. (880 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	LOC102232724	Catenin (cadherin-associated protein), delta 2b. (1236 aa)
	PKP4	Plakophilin 4. (1198 aa)
	kctd10	Potassium channel tetramerization domain containing 10. (308 aa)
	CKB-2	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	arhgap35	Uncharacterized protein. (1552 aa)
	LOC102232213	Potassium channel tetramerization domain containing 13. (376 aa)
	ENSXMAP00000033641	Uncharacterized protein. (1266 aa)
	ubxn11	UBX domain protein 11. (465 aa)
	SEMA4F	Ssemaphorin 4F; Belongs to the semaphorin family. (843 aa)
	ENSXMAP00000034603	Uncharacterized protein. (96 aa)
	LOC102235017	Uncharacterized protein. (329 aa)
	tmod3	Tropomodulin 2. (360 aa)
	ENSXMAP00000035053	Uncharacterized protein. (267 aa)
	rasal2	RAS protein activator like 2. (1386 aa)
	ENSXMAP00000035508	KIND domain-containing protein. (207 aa)
	ddx4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family. (639 aa)
	cpd	Carboxypeptidase D, a. (1362 aa)
	ENSXMAP00000037100	Si:ch211-272n13.3. (300 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	tnfaip1	Tumor necrosis factor, alpha-induced protein 1 (endothelial). (326 aa)
	CCDC88A	Coiled-coil domain containing 88A. (1900 aa)
	ENSXMAP00000041784	DUF3496 domain-containing protein. (514 aa)
	ptpn13	Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2385 aa)
	LOC102224646	Coiled-coil domain containing 88Aa. (1155 aa)
	lemd3	LEM domain containing 3. (830 aa)
	map4	Microtubule-associated protein. (1439 aa)
	flot2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (450 aa)
	VANGL2	VANGL planar cell polarity protein 2. (635 aa)
	rrbp1	Ribosome binding protein 1a. (1130 aa)
	CKB	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	LOC102218395	Coiled-coil domain containing 88C. (1823 aa)
	FLOT2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (441 aa)
	nisch	Nischarin. (1422 aa)
	rnd3	Rho family GTPase 3a. (284 aa)
	LOC102235908	Catenin (cadherin-associated protein), delta 2a. (1262 aa)
	LOC102217702	Vang-like protein. (525 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSXMAP00000022188	LOC102224646	ENSXMAP00000022188	ENSXMAP00000004689	Calponin-homology (CH) domain-containing protein.	Coiled-coil domain containing 88Aa.	0.585
ENSXMAP00000022830	ENSXMAP00000041784	ENSXMAP00000022830	ENSXMAP00000041784	CCDC144C domain-containing protein.	DUF3496 domain-containing protein.	0.612
ENSXMAP00000037100	ENSXMAP00000041784	ENSXMAP00000037100	ENSXMAP00000041784	Si:ch211-272n13.3.	DUF3496 domain-containing protein.	0.542
ENSXMAP00000041784	ENSXMAP00000022830	ENSXMAP00000041784	ENSXMAP00000022830	DUF3496 domain-containing protein.	CCDC144C domain-containing protein.	0.612
ENSXMAP00000041784	ENSXMAP00000037100	ENSXMAP00000041784	ENSXMAP00000037100	DUF3496 domain-containing protein.	Si:ch211-272n13.3.	0.542
FLOT2	LOC102225266	ENSXMAP00000006993	ENSXMAP00000001534	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.460
FLOT2	cav1	ENSXMAP00000006993	ENSXMAP00000025385	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.460
FLOT2	cav3	ENSXMAP00000006993	ENSXMAP00000038231	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.504
LOC102216658	LOC102217702	ENSXMAP00000024015	ENSXMAP00000001154	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Vang-like protein.	0.540
LOC102216658	LOC102219831	ENSXMAP00000024015	ENSXMAP00000012348	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Eph receptor A2 b.	0.427
LOC102216658	LOC102226201	ENSXMAP00000024015	ENSXMAP00000021260	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Eph receptor A2 a.	0.427
LOC102216658	VANGL1	ENSXMAP00000024015	ENSXMAP00000002799	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Vang-like protein.	0.540
LOC102216658	VANGL2	ENSXMAP00000024015	ENSXMAP00000005603	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	VANGL planar cell polarity protein 2.	0.540
LOC102216658	rnd3	ENSXMAP00000024015	ENSXMAP00000007936	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	Rho family GTPase 3a.	0.488
LOC102217211	rnd3	ENSXMAP00000012493	ENSXMAP00000007936	Uncharacterized protein.	Rho family GTPase 3a.	0.410
LOC102217702	LOC102216658	ENSXMAP00000001154	ENSXMAP00000024015	Vang-like protein.	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family.	0.540
LOC102217702	cav3	ENSXMAP00000001154	ENSXMAP00000038231	Vang-like protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.410
LOC102217702	rnd3	ENSXMAP00000001154	ENSXMAP00000007936	Vang-like protein.	Rho family GTPase 3a.	0.430
LOC102217702	rock1	ENSXMAP00000001154	ENSXMAP00000002437	Vang-like protein.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.417
LOC102219781	LOC102232724	ENSXMAP00000011137	ENSXMAP00000026173	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Catenin (cadherin-associated protein), delta 2b.	0.497