(21 nodes) Ras family network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	arhgap5	Rho GTPase activating protein 5. (1499 aa)
	LOC102223553	Zgc:171704. (211 aa)
	LOC102235584	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (1324 aa)
	arhgap35	Uncharacterized protein. (1552 aa)
	rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (618 aa)
	rab28	Uncharacterized protein. (277 aa)
	rem2	RAS (RAD and GEM)-like GTP binding 2. (307 aa)
	LOC102229352	Ras homolog family member T1a. (736 aa)
	LOC102226126	Si:dkeyp-59c12.1. (199 aa)
	rab20	RAB20, member RAS oncogene family. (269 aa)
	LOC102234049	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (1076 aa)
	rergl	RERG/RAS-like b. (206 aa)
	LOC102224464	Uncharacterized protein. (302 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2328 aa)
	rasl10a	RAS-like, family 10, member A. (203 aa)
	rasl11b	RAS-like, family 11, member B. (244 aa)
	LOC102225731	Rho GTPase activating protein 35b. (1529 aa)
	LOC102218104	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1129 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1223 aa)
	lrrk1	Uncharacterized protein. (2017 aa)
	LOC102219294	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (660 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP2	LOC102218104	ENSXMAP00000002433	ENSXMAP00000009517	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	0.902
LOC102218104	AGAP2	ENSXMAP00000009517	ENSXMAP00000002433	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	0.902
LOC102219294	LOC102229352	ENSXMAP00000041596	ENSXMAP00000031300	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Ras homolog family member T1a.	0.901
LOC102219294	rhot2	ENSXMAP00000041596	ENSXMAP00000030301	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.901
LOC102225731	arhgap35	ENSXMAP00000011881	ENSXMAP00000029773	Rho GTPase activating protein 35b.	Uncharacterized protein.	0.901
LOC102225731	arhgap5	ENSXMAP00000011881	ENSXMAP00000024386	Rho GTPase activating protein 35b.	Rho GTPase activating protein 5.	0.901
LOC102229352	LOC102219294	ENSXMAP00000031300	ENSXMAP00000041596	Ras homolog family member T1a.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.901
LOC102229352	rhot2	ENSXMAP00000031300	ENSXMAP00000030301	Ras homolog family member T1a.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.901
arhgap35	LOC102225731	ENSXMAP00000029773	ENSXMAP00000011881	Uncharacterized protein.	Rho GTPase activating protein 35b.	0.901
arhgap35	arhgap5	ENSXMAP00000029773	ENSXMAP00000024386	Uncharacterized protein.	Rho GTPase activating protein 5.	0.901
arhgap5	LOC102225731	ENSXMAP00000024386	ENSXMAP00000011881	Rho GTPase activating protein 5.	Rho GTPase activating protein 35b.	0.901
arhgap5	arhgap35	ENSXMAP00000024386	ENSXMAP00000029773	Rho GTPase activating protein 5.	Uncharacterized protein.	0.901
rhot2	LOC102219294	ENSXMAP00000030301	ENSXMAP00000041596	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.901
rhot2	LOC102229352	ENSXMAP00000030301	ENSXMAP00000031300	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Ras homolog family member T1a.	0.901