(16 nodes) (2021) Whole genome sequencing of a snailfish from the Yap Trench (~7,000 m) clarifies the molecular mechanisms underlying adaptation to the deep sea. network (Xiphophorus maculatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	exo1	Exonuclease 1. (777 aa)
	rad9a	Cell cycle checkpoint control protein; Belongs to the rad9 family. (389 aa)
	LOC102223346	Polycystic kidney disease 2-like 1. (644 aa)
	LOC102217699	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	AANAT	Arylalkylamine N-acetyltransferase 1. (255 aa)
	rad52	RAD52 homolog, DNA repair protein. (445 aa)
	LOC102235421	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	LOC102217954	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (345 aa)
	rad51c	RAD51 paralog C. (352 aa)
	LOC102226079	Arylalkylamine N-acetyltransferase 2. (208 aa)
	COX1	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (518 aa)
	ercc1	Excision repair cross-complementation group 1. (350 aa)
	csf3r	Colony stimulating factor 3 receptor (granulocyte). (837 aa)
	xrcc3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (364 aa)
	cutc	CutC copper transporter homolog (E. coli). (251 aa)
	LOC102225070	Interleukin 12 receptor, beta 2a. (804 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AANAT	LOC102226079	ENSXMAP00000037201	ENSXMAP00000000129	Arylalkylamine N-acetyltransferase 1.	Arylalkylamine N-acetyltransferase 2.	0.903
COX1	exo1	ENSXMAP00000020458	ENSXMAP00000010534	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	Exonuclease 1.	0.564
LOC102217699	LOC102223346	ENSXMAP00000041383	ENSXMAP00000007808	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Polycystic kidney disease 2-like 1.	0.409
LOC102217699	LOC102225070	ENSXMAP00000041383	ENSXMAP00000011696	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Interleukin 12 receptor, beta 2a.	0.564
LOC102217699	csf3r	ENSXMAP00000041383	ENSXMAP00000014758	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Colony stimulating factor 3 receptor (granulocyte).	0.574
LOC102217699	rad51c	ENSXMAP00000041383	ENSXMAP00000003353	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	RAD51 paralog C.	0.444
LOC102217954	LOC102223346	ENSXMAP00000029528	ENSXMAP00000007808	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Polycystic kidney disease 2-like 1.	0.409
LOC102217954	LOC102225070	ENSXMAP00000029528	ENSXMAP00000011696	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Interleukin 12 receptor, beta 2a.	0.564
LOC102217954	csf3r	ENSXMAP00000029528	ENSXMAP00000014758	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Colony stimulating factor 3 receptor (granulocyte).	0.574
LOC102217954	rad51c	ENSXMAP00000029528	ENSXMAP00000003353	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	RAD51 paralog C.	0.444
LOC102223346	LOC102217699	ENSXMAP00000007808	ENSXMAP00000041383	Polycystic kidney disease 2-like 1.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.409
LOC102223346	LOC102217954	ENSXMAP00000007808	ENSXMAP00000029528	Polycystic kidney disease 2-like 1.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.409
LOC102223346	LOC102225070	ENSXMAP00000007808	ENSXMAP00000011696	Polycystic kidney disease 2-like 1.	Interleukin 12 receptor, beta 2a.	0.425
LOC102223346	LOC102235421	ENSXMAP00000007808	ENSXMAP00000033354	Polycystic kidney disease 2-like 1.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.409
LOC102223346	csf3r	ENSXMAP00000007808	ENSXMAP00000014758	Polycystic kidney disease 2-like 1.	Colony stimulating factor 3 receptor (granulocyte).	0.459
LOC102223346	ercc1	ENSXMAP00000007808	ENSXMAP00000015840	Polycystic kidney disease 2-like 1.	Excision repair cross-complementation group 1.	0.409
LOC102223346	exo1	ENSXMAP00000007808	ENSXMAP00000010534	Polycystic kidney disease 2-like 1.	Exonuclease 1.	0.508
LOC102223346	rad51c	ENSXMAP00000007808	ENSXMAP00000003353	Polycystic kidney disease 2-like 1.	RAD51 paralog C.	0.401
LOC102223346	rad9a	ENSXMAP00000007808	ENSXMAP00000009919	Polycystic kidney disease 2-like 1.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.460
LOC102225070	LOC102217699	ENSXMAP00000011696	ENSXMAP00000041383	Interleukin 12 receptor, beta 2a.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.564