(55 nodes) Amino sugar and nucleotide sugar metabolism network (Xiphophorus maculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102231329	Glutamine--fructose-6-phosphate transaminase 1. (682 aa)
	pgm1	Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (561 aa)
	galt	Galactose-1-phosphate uridylyltransferase; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (356 aa)
	LOC102223025	Chitinase, acidic.3; Belongs to the glycosyl hydrolase 18 family. (469 aa)
	LOC111605809	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (454 aa)
	gmppa	GDP-mannose pyrophosphorylase Ab. (427 aa)
	LOC102226750	Hexokinase 2. (916 aa)
	renbp	Renin binding protein. (397 aa)
	LOC102229508	UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
	LOC102234677	UTP--glucose-1-phosphate uridylyltransferase. (504 aa)
	tsta3	Tissue specific transplantation antigen P35B. (315 aa)
	gmds	GDP-mannose 4,6-dehydratase. (399 aa)
	LOC102224063	Cytidine monophospho-N-acetylneuraminic acid hydroxylase. (593 aa)
	fcsk	Fucose kinase. (1088 aa)
	LOC102237407	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	pgm3	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (545 aa)
	galk1	Galactokinase 1. (393 aa)
	LOC102226546	Glucuronokinase with putative uridyl pyrophosphorylase. (495 aa)
	LOC102236979	Glutamine-fructose-6-phosphate transaminase 2. (685 aa)
	nagk	N-acetylglucosamine kinase. (349 aa)
	LOC102230600	Rieske domain-containing protein. (595 aa)
	uap1	UDP-N-acetylglucosamine pyrophosphorylase 1. (520 aa)
	pgm2	Phosphoglucomutase 2. (611 aa)
	mpi	Mannose phosphate isomerase. (422 aa)
	npl	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); Belongs to the DapA family. (305 aa)
	fpgt	Fucose-1-phosphate guanylyltransferase. (579 aa)
	gmppb	GDP-mannose pyrophosphorylase B. (360 aa)
	LOC102222010	Hexokinase domain containing 1. (934 aa)
	LOC102216731	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (304 aa)
	LOC102222329	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (474 aa)
	uap1l1	UDP-N-acetylglucosamine pyrophosphorylase 1, like 1. (504 aa)
	LOC102235298	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (299 aa)
	gale	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (352 aa)
	LOC102226091	Uncharacterized protein; Belongs to the phosphohexose mutase family. (564 aa)
	gnpnat1	Glucosamine 6-phosphate N-acetyltransferase. (184 aa)
	gpi	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	LOC102232392	Phosphotransferase. (491 aa)
	nanp	N-acetylneuraminic acid phosphatase. (243 aa)
	hexb	Beta-hexosaminidase. (549 aa)
	gck	Phosphotransferase. (478 aa)
	LOC102227832	Uncharacterized protein. (923 aa)
	LOC102229320	Beta-hexosaminidase. (530 aa)
	LOC102220922	Glucosamine-6-phosphate isomerase. (275 aa)
	gne	Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (764 aa)
	LOC102216980	Uncharacterized protein. (466 aa)
	LOC102228980	Hexokinase 1. (931 aa)
	amdhd2	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (406 aa)
	nans	N-acetylneuraminic acid synthase a. (359 aa)
	ugdh	UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (496 aa)
	LOC102216714	Chitin synthase 1. (1423 aa)
	gnpda2	Glucosamine-6-phosphate isomerase. (277 aa)
	LOC102231992	Cytochrome b5 reductase 4. (531 aa)
	LOC102216741	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family. (454 aa)
	LOC102216878	Uncharacterized protein. (465 aa)
	LOC102225448	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (492 aa)

Your Current Organism:

Xiphophorus maculatus

NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102216714	gne	ENSXMAP00000034920	ENSXMAP00000031439	Chitin synthase 1.	Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase.	0.900
LOC102216714	uap1	ENSXMAP00000034920	ENSXMAP00000011766	Chitin synthase 1.	UDP-N-acetylglucosamine pyrophosphorylase 1.	0.935
LOC102216714	uap1l1	ENSXMAP00000034920	ENSXMAP00000016801	Chitin synthase 1.	UDP-N-acetylglucosamine pyrophosphorylase 1, like 1.	0.935
LOC102216731	LOC102224063	ENSXMAP00000015600	ENSXMAP00000006398	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytidine monophospho-N-acetylneuraminic acid hydroxylase.	0.900
LOC102216731	LOC102230600	ENSXMAP00000015600	ENSXMAP00000010021	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Rieske domain-containing protein.	0.900
LOC102216731	LOC102231992	ENSXMAP00000015600	ENSXMAP00000037312	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Cytochrome b5 reductase 4.	0.957
LOC102216731	LOC102235298	ENSXMAP00000015600	ENSXMAP00000017454	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.902
LOC102216741	LOC102229320	ENSXMAP00000038527	ENSXMAP00000029868	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase.	0.947
LOC102216741	hexb	ENSXMAP00000038527	ENSXMAP00000026394	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase.	0.947
LOC102216741	nagk	ENSXMAP00000038527	ENSXMAP00000008845	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family.	N-acetylglucosamine kinase.	0.900
LOC102216741	renbp	ENSXMAP00000038527	ENSXMAP00000004842	Oviductal glycoprotein 1; Belongs to the glycosyl hydrolase 18 family.	Renin binding protein.	0.900
LOC102216878	LOC102216980	ENSXMAP00000039258	ENSXMAP00000031656	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC102216878	LOC102224063	ENSXMAP00000039258	ENSXMAP00000006398	Uncharacterized protein.	Cytidine monophospho-N-acetylneuraminic acid hydroxylase.	0.910
LOC102216878	LOC102230600	ENSXMAP00000039258	ENSXMAP00000010021	Uncharacterized protein.	Rieske domain-containing protein.	0.910
LOC102216878	nanp	ENSXMAP00000039258	ENSXMAP00000024523	Uncharacterized protein.	N-acetylneuraminic acid phosphatase.	0.923
LOC102216878	nans	ENSXMAP00000039258	ENSXMAP00000032659	Uncharacterized protein.	N-acetylneuraminic acid synthase a.	0.958
LOC102216980	LOC102216878	ENSXMAP00000031656	ENSXMAP00000039258	Uncharacterized protein.	Uncharacterized protein.	0.901
LOC102216980	LOC102224063	ENSXMAP00000031656	ENSXMAP00000006398	Uncharacterized protein.	Cytidine monophospho-N-acetylneuraminic acid hydroxylase.	0.910
LOC102216980	LOC102230600	ENSXMAP00000031656	ENSXMAP00000010021	Uncharacterized protein.	Rieske domain-containing protein.	0.910
LOC102216980	nanp	ENSXMAP00000031656	ENSXMAP00000024523	Uncharacterized protein.	N-acetylneuraminic acid phosphatase.	0.923