STRINGSTRING
ddb1 ddb1 ercc6 ercc6 rfc5 rfc5 gtf2h5 gtf2h5 pole4 pole4 ercc3 ercc3 gtf2h1 gtf2h1 lig1 lig1 pold3 pold3 pole pole ercc4 ercc4 pole2 pole2 rad23a rad23a LOC102228171 LOC102228171 rfc1 rfc1 RPA1 RPA1 pold1 pold1 mnat1 mnat1 gtf2h4 gtf2h4 cul4b cul4b pold4 pold4 RAD23B RAD23B rpa2 rpa2 pcna pcna pold2 pold2 ercc8 ercc8 ercc1 ercc1 ercc5 ercc5 xpc xpc ccnh ccnh ddb2 ddb2 xpa xpa rfc2 rfc2 rfc4 rfc4 rbx1 rbx1 rpa3 rpa3 cdk7 cdk7 ercc2 ercc2 LOC102230232 LOC102230232 rpa1 rpa1 pole3 pole3 LOC102217136 LOC102217136 rfc3 rfc3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ddb1Damage-specific DNA binding protein 1. (1081 aa)
ercc6Excision repair cross-complementation group 6. (1470 aa)
rfc5Replication factor C (activator 1) 5. (335 aa)
gtf2h5General transcription factor IIH, polypeptide 5. (71 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (129 aa)
ercc3Excision repair cross-complementation group 3. (783 aa)
gtf2h1General transcription factor IIH, polypeptide 1. (550 aa)
lig1DNA ligase. (595 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (438 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2281 aa)
ercc4Excision repair cross-complementation group 4. (893 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa)
rad23aRAD23 homolog A, nucleotide excision repair protein a. (369 aa)
LOC102228171Centrin, EF-hand protein, 2. (174 aa)
rfc1Replication factor C subunit 1. (1195 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (700 aa)
pold1DNA polymerase. (1105 aa)
mnat1MNAT1 component of CDK activating kinase. (291 aa)
gtf2h4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (464 aa)
cul4bCullin 4B; Belongs to the cullin family. (867 aa)
pold4Si:dkey-28b4.7. (108 aa)
RAD23BRAD23 homolog B, nucleotide excision repair protein. (394 aa)
rpa2Replication protein A2. (278 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (528 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
ercc1Excision repair cross-complementation group 1. (350 aa)
ercc5Excision repair cross-complementation group 5. (1097 aa)
xpcXeroderma pigmentosum, complementation group C. (934 aa)
ccnhCyclin H; Belongs to the cyclin family. (319 aa)
ddb2Damage-specific DNA binding protein 2. (490 aa)
xpaXeroderma pigmentosum, complementation group A. (276 aa)
rfc2Replication factor C (activator 1) 2. (357 aa)
rfc4Replication factor C (activator 1) 4. (357 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (149 aa)
rpa3Replication protein A3. (122 aa)
cdk7Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
LOC102230232RPA_C domain-containing protein. (247 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (600 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
LOC102217136General transcription factor IIH subunit. (392 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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