STRINGSTRING
LOC102225395 LOC102225395 nprl3 nprl3 LOC102219029 LOC102219029 rheb rheb LOC102225386 LOC102225386 LOC102227689 LOC102227689 Mtor Mtor wnt6 wnt6 LOC102238002 LOC102238002 LOC102237095 LOC102237095 atp6v1c1 atp6v1c1 LOC102236577 LOC102236577 seh1l seh1l LOC102225926 LOC102225926 lrp6 lrp6 LOC102218432 LOC102218432 LOC102229074 LOC102229074 LOC102224028 LOC102224028 map2k1 map2k1 LOC102233783 LOC102233783 gsk3b gsk3b LOC102229577 LOC102229577 wnt2 wnt2 LOC102234531 LOC102234531 LOC102225882 LOC102225882 lpin1 lpin1 rps6kb2 rps6kb2 tti1 tti1 LOC102223583 LOC102223583 LOC102221578 LOC102221578 grb2 grb2 LOC102223352 LOC102223352 LOC102220204 LOC102220204 wnt3a wnt3a wnt9a wnt9a ulk2 ulk2 rps6 rps6 LOC102218548 LOC102218548 LOC102226568 LOC102226568 mapk1 mapk1 PRKCA PRKCA akt1 akt1 WNT7A WNT7A slc38a9 slc38a9 STRADB STRADB LOC102229429 LOC102229429 eif4e2 eif4e2 LOC102218230 LOC102218230 slc3a2 slc3a2 wnt4 wnt4 prr5 prr5 LOC102223878 LOC102223878 Wnt16 Wnt16 atp6v1a atp6v1a LOC102228256 LOC102228256 LOC102226088 LOC102226088 wnt10b wnt10b prkaa2 prkaa2 LOC102232995 LOC102232995 rps6ka6 rps6ka6 flcn flcn LOC102229095 LOC102229095 ATP6V1B2 ATP6V1B2 akt2 akt2 pten pten ATP6V1A ATP6V1A LOC102236796 LOC102236796 LOC102222201 LOC102222201 wnt11 wnt11 LOC102216436 LOC102216436 LOC102216940 LOC102216940 akt1s1 akt1s1 LOC102220269 LOC102220269 LOC102235425 LOC102235425 LOC102230854 LOC102230854 rictor rictor atp6v1f atp6v1f dvl2 dvl2 LOC102224423 LOC102224423 lamtor3 lamtor3 slc7a5 slc7a5 LOC102219925 LOC102219925 prkaa1 prkaa1 LOC102222710 LOC102222710 nprl2 nprl2 Fzd9 Fzd9 LOC102229098 LOC102229098 LOC102221099 LOC102221099 atp6v1h atp6v1h LOC102233666 LOC102233666 LOC102237234 LOC102237234 LOC102236366 LOC102236366 LOC102237852 LOC102237852 pik3r1 pik3r1 mios mios pdpk1 pdpk1 LOC102235687 LOC102235687 wdr24 wdr24 LOC102233479 LOC102233479 stk11 stk11 sec13 sec13 LOC102229174 LOC102229174 Fzd8 Fzd8 LOC102226874 LOC102226874 Fzd10 Fzd10 LOC102237243 LOC102237243 M4B140_XIPMA M4B140_XIPMA rps6ka3 rps6ka3 LOC102226157 LOC102226157 LOC102227289 LOC102227289 LOC102225527 LOC102225527 LOC102229304 LOC102229304 LOC111609451 LOC111609451 pik3cb pik3cb igf1 igf1 insr insr PRKCB PRKCB pik3r3 pik3r3 CASTOR1 CASTOR1 LOC102230982 LOC102230982 hras hras rptor rptor castor2 castor2 LOC102237756 LOC102237756 ikbkb ikbkb lamtor4 lamtor4 LOC102238407 LOC102238407 LOC102235344 LOC102235344 LOC102234512 LOC102234512 LOC102232337 LOC102232337 LOC102237032 LOC102237032 ddit4 ddit4 map2k2 map2k2 fnip1 fnip1 clip1 clip1 ulk1 ulk1 mlst8 mlst8 LOC102232504 LOC102232504 rragc rragc sos1 sos1 pik3cd pik3cd LOC102231253 LOC102231253 fzd6 fzd6 ins ins dvl1 dvl1 SGK1 SGK1 lamtor1 lamtor1 LOC102221045 LOC102221045 lamtor2 lamtor2 wnt3 wnt3 fzd4 fzd4 LOC102233859 LOC102233859 eif4b eif4b lamtor5 lamtor5 wnt1 wnt1 ENSXMAP00000035407 ENSXMAP00000035407 LOC102225385 LOC102225385 LOC102237954 LOC102237954 cab39 cab39 LOC102229029 LOC102229029 LOC102233685 LOC102233685 LOC102233436 LOC102233436 deptor deptor lrp5 lrp5 braf braf LOC102228807 LOC102228807 tnfrsf1a tnfrsf1a LOC102228510 LOC102228510 CHUK CHUK atp6v1d atp6v1d LOC102224351 LOC102224351 LOC102235279 LOC102235279 sos2 sos2 LOC102228928 LOC102228928 strada strada wnt8b wnt8b mapkap1 mapkap1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102225395Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
nprl3NPR3-like, GATOR1 complex subunit. (574 aa)
LOC102219029TSC complex subunit 1. (977 aa)
rhebUncharacterized protein. (183 aa)
LOC102225386Growth factor receptor-bound protein 10b. (622 aa)
LOC102227689Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
MtorSerine/threonine-protein kinase TOR. (1011 aa)
wnt6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
LOC102238002Unc-51 like autophagy activating kinase 1a. (892 aa)
LOC102237095Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
atp6v1c1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (383 aa)
LOC102236577Uncharacterized protein. (408 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (383 aa)
LOC102225926Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)
lrp6Low density lipoprotein receptor-related protein 6. (1610 aa)
LOC102218432Sestrin 2. (558 aa)
LOC102229074Uncharacterized protein. (213 aa)
LOC102224028Uncharacterized protein. (471 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
LOC102233783Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (503 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (423 aa)
LOC102229577Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
wnt2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
LOC102234531Uncharacterized protein. (193 aa)
LOC102225882Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
lpin1Si:ch73-21k16.1. (902 aa)
rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
tti1TELO2 interacting protein 1. (1108 aa)
LOC102223583Solute carrier family 3 member 2b. (566 aa)
LOC102221578IlGF domain-containing protein. (193 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC102223352ATPase H+ transporting V1 subunit E1a. (226 aa)
LOC102220204ATPase H+ transporting V1 subunit E1b. (226 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
wnt9aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (369 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1041 aa)
rps640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (256 aa)
LOC102218548Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (384 aa)
LOC102226568TBC1 domain family, member 7. (291 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (368 aa)
slc38a9Solute carrier family 38 member 9. (565 aa)
STRADBSTE20 related adaptor beta. (408 aa)
LOC102229429Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
eif4e2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (250 aa)
LOC102218230Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
slc3a2Uncharacterized protein. (492 aa)
wnt4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
prr5Proline rich 5a (renal). (459 aa)
LOC102223878Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Wnt16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (240 aa)
atp6v1aATPase H+ transporting V1 subunit A. (617 aa)
LOC102228256Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
LOC102226088Component of inhibitor of nuclear factor kappa B kinase complex. (733 aa)
wnt10bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (429 aa)
prkaa2Non-specific serine/threonine protein kinase. (629 aa)
LOC102232995Zgc:55558. (187 aa)
rps6ka6Ribosomal protein S6 kinase. (727 aa)
flcnFolliculin. (551 aa)
LOC102229095Ras-related GTP binding A. (315 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (525 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (441 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
LOC102236796Uncharacterized protein. (384 aa)
LOC102222201Growth factor receptor-bound protein 10a. (603 aa)
wnt11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
LOC102216436Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (728 aa)
LOC102216940Uncharacterized protein. (603 aa)
akt1s1AKT1 substrate 1 (proline-rich). (351 aa)
LOC102220269Ribosomal protein S6 kinase. (794 aa)
LOC102235425Uncharacterized protein. (726 aa)
LOC102230854Eukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (194 aa)
rictorRPTOR independent companion of MTOR, complex 2 a. (1724 aa)
atp6v1fV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
dvl2Dishevelled segment polarity protein 2. (763 aa)
LOC102224423Si:ch73-335l21.1. (1276 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
slc7a5Solute carrier family 7 member 5. (519 aa)
LOC102219925Uncharacterized protein. (537 aa)
prkaa1Non-specific serine/threonine protein kinase. (564 aa)
LOC102222710Ras homolog gene family, member Ab. (193 aa)
nprl2NPR2 like, GATOR1 complex subunit. (378 aa)
Fzd9Frizzled class receptor 9b; Belongs to the G-protein coupled receptor Fz/Smo family. (588 aa)
LOC102229098Calcium binding protein 39-like. (334 aa)
LOC102221099Lipin 1. (960 aa)
atp6v1hV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (484 aa)
LOC102233666Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
LOC102237234Uncharacterized protein. (119 aa)
LOC102236366Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (422 aa)
LOC102237852Zgc:123305. (985 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
miosMissing oocyte, meiosis regulator, homolog (Drosophila). (867 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
LOC102235687Ribosomal protein S6 kinase. (769 aa)
wdr24WD repeat domain 24. (783 aa)
LOC102233479Dishevelled segment polarity protein 3a. (686 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
LOC102229174Uncharacterized protein. (193 aa)
Fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
LOC102226874Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (542 aa)
Fzd10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
LOC102237243Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (559 aa)
M4B140_XIPMAUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (562 aa)
rps6ka3Ribosomal protein S6 kinase. (756 aa)
LOC102226157Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1152 aa)
LOC102227289Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC102225527Uncharacterized protein. (193 aa)
LOC102229304Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
LOC111609451V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
igf1Insulin-like growth factor 1. (186 aa)
insrTyrosine-protein kinase receptor. (1337 aa)
PRKCBProtein kinase C beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (842 aa)
pik3r3Uncharacterized protein. (473 aa)
CASTOR1Cytosolic arginine sensor for mTORC1 subunit 1. (334 aa)
LOC102230982Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (210 aa)
hrasHRas proto-oncogene, GTPase a. (211 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1381 aa)
castor2Cytosolic arginine sensor for mTORC1 subunit 2. (328 aa)
LOC102237756TSC complex subunit 1b. (1243 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (743 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (100 aa)
LOC102238407Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
LOC102235344Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
LOC102234512Ras homolog, mTORC1 binding like 1. (223 aa)
LOC102232337Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
LOC102237032Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
ddit4DNA-damage-inducible transcript 4. (275 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
fnip1Folliculin interacting protein 1. (1218 aa)
clip1CAP-GLY domain containing linker protein 1a. (2206 aa)
ulk1Unc-51 like autophagy activating kinase 1. (1064 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
LOC102232504Non-specific serine/threonine protein kinase. (503 aa)
rragcRas-related GTP binding Ca. (382 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1342 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC102231253Tumor necrosis factor a (TNF superfamily, member 2). (245 aa)
fzd6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (692 aa)
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (140 aa)
dvl1Dishevelled segment polarity protein 1a. (720 aa)
SGK1Non-specific serine/threonine protein kinase. (612 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
LOC102221045Tyrosine-protein kinase receptor. (1416 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
wnt3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (531 aa)
LOC102233859Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (498 aa)
eif4bEukaryotic translation initiation factor 4Bb. (640 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ENSXMAP00000035407FZ domain-containing protein. (199 aa)
LOC102225385Calcium binding protein 39, like 1. (343 aa)
LOC102237954Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
cab39Calcium binding protein 39. (341 aa)
LOC102229029Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (727 aa)
LOC102233685Uncharacterized protein. (193 aa)
LOC102233436Uncharacterized protein. (466 aa)
deptorDEP domain containing MTOR-interacting protein. (425 aa)
lrp5Low density lipoprotein receptor-related protein 5. (1649 aa)
brafB-Raf proto-oncogene, serine/threonine kinase. (783 aa)
LOC102228807Lipin 2. (949 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (365 aa)
LOC102228510Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (345 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (798 aa)
atp6v1dATPase H+ transporting V1 subunit D. (248 aa)
LOC102224351Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (431 aa)
LOC102235279Tyrosine-protein kinase receptor. (1386 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1323 aa)
LOC102228928Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
stradaSTE20 related adaptor alpha. (428 aa)
wnt8bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (379 aa)
mapkap1MAPK associated protein 1. (525 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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