STRINGSTRING
LOC102219604 LOC102219604 fadd fadd actb actb LOC102232631 LOC102232631 itpr2 itpr2 ern1 ern1 LOC102238210 LOC102238210 LOC102230901 LOC102230901 LOC102217419 LOC102217419 eif2ak3 eif2ak3 LOC102236577 LOC102236577 LOC102223838 LOC102223838 ctsh ctsh ctsz ctsz map2k1 map2k1 parp1 parp1 LOC102222087 LOC102222087 LOC102235885 LOC102235885 pidd1 pidd1 LOC102224057 LOC102224057 CASP3 CASP3 ikbkg ikbkg mapk10 mapk10 LOC102230681 LOC102230681 LOC102225882 LOC102225882 LOC102227944 LOC102227944 dffb dffb parp2 parp2 LOC102226708 LOC102226708 mapk1 mapk1 akt1 akt1 LOC102236946 LOC102236946 LOC102216697 LOC102216697 lmnb2 lmnb2 LOC102232234 LOC102232234 itpr1 itpr1 LOC102217715 LOC102217715 LOC102218230 LOC102218230 LOC102232073 LOC102232073 LOC102234145 LOC102234145 LOC102230067 LOC102230067 LOC102230330 LOC102230330 LOC102221075 LOC102221075 BAX BAX LOC106700271 LOC106700271 nfkbia nfkbia BCL2L1 BCL2L1 casp6 casp6 LOC102220811 LOC102220811 LOC102226088 LOC102226088 LOC102228435 LOC102228435 LOC102237850 LOC102237850 tuba4a tuba4a birc2 birc2 LOC102230347 LOC102230347 LOC102218059 LOC102218059 LOC102219274 LOC102219274 LOC102237443 LOC102237443 LOC102219636 LOC102219636 casp2 casp2 LOC102232995 LOC102232995 LOC102217801 LOC102217801 LOC102229982 LOC102229982 aifm1 aifm1 LOC102230245 LOC102230245 LOC106699834 LOC106699834 akt2 akt2 GADD45B GADD45B htra2 htra2 LOC102217423 LOC102217423 LOC102216436 LOC102216436 LOC102227213 LOC102227213 tradd tradd M4AKB2_XIPMA M4AKB2_XIPMA LOC102235425 LOC102235425 LOC102227221 LOC102227221 LOC102218394 LOC102218394 cflar cflar LOC102223550 LOC102223550 LOC102224061 LOC102224061 gadd45g gadd45g lmnb1 lmnb1 LOC102235269 LOC102235269 ripk1 ripk1 LOC111605760 LOC111605760 LOC102229156 LOC102229156 LOC102229416 LOC102229416 ddit3 ddit3 LOC102236865 LOC102236865 LOC102237127 LOC102237127 dab2ip dab2ip ctsd ctsd pik3r1 pik3r1 pdpk1 pdpk1 casp9 casp9 jun jun LOC102232576 LOC102232576 LOC102226157 LOC102226157 LOC102222672 LOC102222672 LOC102229979 LOC102229979 LOC102230859 LOC102230859 bcl2l1 bcl2l1 LOC102223804 LOC102223804 pik3cb pik3cb LOC102221968 LOC102221968 LOC102227133 LOC102227133 LOC102234824 LOC102234824 pik3r3 pik3r3 LOC102232209 LOC102232209 LOC102217350 LOC102217350 LOC102237237 LOC102237237 hras hras LOC102232031 LOC102232031 ENSXMAP00000025330 ENSXMAP00000025330 bad bad ENSXMAP00000025381 ENSXMAP00000025381 ikbkb ikbkb LOC102237609 LOC102237609 parp3 parp3 ctsc ctsc eif2s1 eif2s1 casp7 casp7 LOC102219838 LOC102219838 LOC102218092 LOC102218092 LOC102237032 LOC102237032 LOC102224158 LOC102224158 LOC102224137 LOC102224137 tp53 tp53 map2k2 map2k2 ctso ctso LOC102232504 LOC102232504 LOC102216951 LOC102216951 pik3cd pik3cd LOC102231253 LOC102231253 ENSXMAP00000032129 ENSXMAP00000032129 LOC102225495 LOC102225495 LOC102218762 LOC102218762 LOC102217348 LOC102217348 LOC102233408 LOC102233408 LOC102222747 LOC102222747 dffa dffa GADD45B-2 GADD45B-2 LOC102233955 LOC102233955 bcl2 bcl2 mapk8 mapk8 LOC102216404 LOC102216404 LOC102225207 LOC102225207 LOC102222042 LOC102222042 LOC102234094 LOC102234094 LOC102237954 LOC102237954 LOC102217235 LOC102217235 LOC102233436 LOC102233436 LOC102217094 LOC102217094 tnfrsf1a tnfrsf1a LOC102226394 LOC102226394 apaf1 apaf1 CHUK CHUK map3k5 map3k5 LOC102221406 LOC102221406 LOC102224562 LOC102224562 gadd45a gadd45a LOC102224281 LOC102224281 Sptan1 Sptan1 LOC102218392 LOC102218392 LOC102237985 LOC102237985 bcl2l11 bcl2l11 LOC102223022 LOC102223022 endog endog
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102219604Calpain 14; Belongs to the peptidase C2 family. (694 aa)
faddUncharacterized protein. (196 aa)
actbUncharacterized protein. (378 aa)
LOC102232631Uncharacterized protein. (699 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2636 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1060 aa)
LOC102238210Zgc:153993. (189 aa)
LOC102230901Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
LOC102217419Inositol 1,4,5-trisphosphate receptor, type 1a. (2694 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1101 aa)
LOC102236577Uncharacterized protein. (408 aa)
LOC102223838Activating transcription factor 4b. (434 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (325 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (303 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (394 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1015 aa)
LOC102222087Cathepsin Bb; Belongs to the peptidase C1 family. (330 aa)
LOC102235885Uncharacterized protein; Belongs to the peptidase C1 family. (348 aa)
pidd1P53-induced death domain protein 1. (942 aa)
LOC102224057V-fos FBJ murine osteosarcoma viral oncogene homolog Ab. (364 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (301 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (583 aa)
mapk10Mitogen-activated protein kinase. (401 aa)
LOC102230681TNF superfamily member 10; Belongs to the tumor necrosis factor family. (280 aa)
LOC102225882Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC102227944TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (346 aa)
parp2Poly [ADP-ribose] polymerase. (509 aa)
LOC102226708Calpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (712 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
akt1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
LOC102236946X-linked inhibitor of apoptosis. (401 aa)
LOC102216697Uncharacterized protein; Belongs to the intermediate filament family. (643 aa)
lmnb2Lamin B2; Belongs to the intermediate filament family. (579 aa)
LOC102232234Activating transcription factor 4a. (424 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1b. (2671 aa)
LOC102217715Zgc:55262; Belongs to the peptidase C2 family. (706 aa)
LOC102218230Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC102232073Calpain 1, (mu/I) large subunit b; Belongs to the peptidase C2 family. (702 aa)
LOC102234145Calpain 2, (m/II) large subunit b; Belongs to the peptidase C2 family. (697 aa)
LOC102230067Cathepsin K; Belongs to the peptidase C1 family. (330 aa)
LOC102230330Cathepsin S, ortholog2, tandem duplicate 1; Belongs to the peptidase C1 family. (335 aa)
LOC102221075TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (289 aa)
BAXBCL2 associated X, apoptosis regulator. (190 aa)
LOC106700271Uncharacterized protein. (207 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (386 aa)
BCL2L1BCL2 like 1. (219 aa)
casp6Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (298 aa)
LOC102220811Uncharacterized protein. (377 aa)
LOC102226088Component of inhibitor of nuclear factor kappa B kinase complex. (733 aa)
LOC102228435Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC102237850Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (509 aa)
tuba4aTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
birc2Baculoviral IAP repeat containing 2. (642 aa)
LOC102230347Cathepsin 12; Belongs to the peptidase C1 family. (337 aa)
LOC102218059Baculoviral IAP repeat containing 5a. (142 aa)
LOC102219274Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (402 aa)
LOC102237443Uncharacterized protein; Belongs to the peptidase C14A family. (395 aa)
LOC102219636V-rel avian reticuloendotheliosis viral oncogene homolog A. (629 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (463 aa)
LOC102232995Zgc:55558. (187 aa)
LOC102217801Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (301 aa)
LOC102229982Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (248 aa)
aifm1Apoptosis inducing factor mitochondrion associated 1. (650 aa)
LOC102230245Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (238 aa)
LOC106699834Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (240 aa)
akt2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
GADD45BGrowth arrest and DNA damage inducible beta. (160 aa)
htra2Si:dkey-33c12.12. (445 aa)
LOC102217423Tyrosine-protein kinase receptor. (802 aa)
LOC102216436Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (728 aa)
LOC102227213Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
traddTnfrsf1a-associated via death domain. (293 aa)
M4AKB2_XIPMAUncharacterized protein. (484 aa)
LOC102235425Uncharacterized protein. (726 aa)
LOC102227221Perforin 1.5. (523 aa)
LOC102218394Uncharacterized protein. (375 aa)
cflarUncharacterized protein; Belongs to the peptidase C14A family. (422 aa)
LOC102223550Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (494 aa)
LOC102224061Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
gadd45gGrowth arrest and DNA-damage-inducible, gamma a. (159 aa)
lmnb1Lamin B1; Belongs to the intermediate filament family. (584 aa)
LOC102235269ADP-ribosylation factor 2b. (932 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (676 aa)
LOC111605760Diablo, IAP-binding mitochondrial protein a. (251 aa)
LOC102229156Uncharacterized protein. (568 aa)
LOC102229416Uncharacterized protein. (572 aa)
ddit3DNA-damage-inducible transcript 3. (311 aa)
LOC102236865Uncharacterized protein. (611 aa)
LOC102237127Uncharacterized protein. (614 aa)
dab2ipDAB2 interacting protein b. (1246 aa)
ctsdCathepsin D; Belongs to the peptidase A1 family. (396 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (727 aa)
pdpk13-phosphoinositide dependent protein kinase 1b. (565 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (434 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (329 aa)
LOC102232576Nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain. (194 aa)
LOC102226157Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1152 aa)
LOC102222672Si:ch211-153j24.3. (431 aa)
LOC102229979Uncharacterized protein. (543 aa)
LOC102230859MCL1 apoptosis regulator, BCL2 family member b. (280 aa)
bcl2l1BH4_2 domain-containing protein. (227 aa)
LOC102223804Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (463 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
LOC102221968Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC102227133Uncharacterized protein; Belongs to the peptidase C2 family. (700 aa)
LOC102234824Ribosomal_L7Ae domain-containing protein. (157 aa)
pik3r3Uncharacterized protein. (473 aa)
LOC102232209Uncharacterized protein. (319 aa)
LOC102217350TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (597 aa)
LOC102237237Mitogen-activated protein kinase. (420 aa)
hrasHRas proto-oncogene, GTPase a. (211 aa)
LOC102232031Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (300 aa)
ENSXMAP00000025330Uncharacterized protein. (1003 aa)
badBCL2 associated agonist of cell death b. (166 aa)
ENSXMAP00000025381Peptidase S1 domain-containing protein. (124 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (743 aa)
LOC102237609Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
parp3Poly [ADP-ribose] polymerase. (539 aa)
ctscCathepsin C; Belongs to the peptidase C1 family. (455 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
casp7Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (320 aa)
LOC102219838Uncharacterized protein. (568 aa)
LOC102218092Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
LOC102237032Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
LOC102224158Baculoviral IAP repeat containing 5b. (148 aa)
LOC102224137Mitogen-activated protein kinase kinase kinase 14a. (869 aa)
tp53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (342 aa)
map2k2Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
ctsoCathepsin O; Belongs to the peptidase C1 family. (330 aa)
LOC102232504Non-specific serine/threonine protein kinase. (503 aa)
LOC102216951MACPF domain-containing protein. (450 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC102231253Tumor necrosis factor a (TNF superfamily, member 2). (245 aa)
ENSXMAP00000032129Uncharacterized protein. (530 aa)
LOC102225495Diablo, IAP-binding mitochondrial protein a. (229 aa)
LOC102218762Uncharacterized protein. (251 aa)
LOC102217348Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
LOC102233408TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
LOC102222747Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (358 aa)
dffaDNA fragmentation factor, alpha polypeptide. (314 aa)
GADD45B-2Growth arrest and DNA damage inducible beta. (153 aa)
LOC102233955Cathepsin F; Belongs to the peptidase C1 family. (471 aa)
bcl2BCL2 apoptosis regulator b. (229 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
LOC102216404Lamin A; Belongs to the intermediate filament family. (660 aa)
LOC102225207Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (397 aa)
LOC102222042Protein kinase domain-containing protein. (1036 aa)
LOC102234094Mitogen-activated protein kinase. (457 aa)
LOC102237954Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
LOC102217235Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (434 aa)
LOC102233436Uncharacterized protein. (466 aa)
LOC102217094Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (365 aa)
LOC102226394Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
apaf1Apoptotic peptidase activating factor 1. (1299 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (798 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1366 aa)
LOC102221406Tumor necrosis factor receptor superfamily, member a. (445 aa)
LOC102224562CD40 ligand; Belongs to the tumor necrosis factor family. (237 aa)
gadd45aGrowth arrest and DNA-damage-inducible, alpha, a. (162 aa)
LOC102224281Cytochrome c, somatic b; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
Sptan1Uncharacterized protein. (190 aa)
LOC102218392Uncharacterized protein; Belongs to the peptidase C14A family. (296 aa)
LOC102237985Uncharacterized protein; Belongs to the peptidase C1 family. (331 aa)
bcl2l11Uncharacterized protein. (250 aa)
LOC102223022V-fos FBJ murine osteosarcoma viral oncogene homolog Aa. (381 aa)
endogEndonuclease. (300 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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