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cacng3 cacng3 LOC102237830 LOC102237830 LOC102227478 LOC102227478 LOC102229283 LOC102229283 LOC102218802 LOC102218802 LOC102221483 LOC102221483 LOC102224767 LOC102224767 LOC102219848 LOC102219848 LOC102219450 LOC102219450 LOC102233799 LOC102233799 LOC102221223 LOC102221223 tpm4 tpm4 LOC102226217 LOC102226217 LOC102237528 LOC102237528 MYL2 MYL2 LOC102226226 LOC102226226 LOC102233017 LOC102233017 LOC102220863 LOC102220863 LOC102222505 LOC102222505 LOC102229576 LOC102229576 CACNG1 CACNG1 LOC102220985 LOC102220985 LOC102233599 LOC102233599 LOC102218145 LOC102218145 LOC102221627 LOC102221627 ACTC1 ACTC1 LOC102228764 LOC102228764 LOC102230071 LOC102230071 LOC102221379 LOC102221379 LOC102231053 LOC102231053 LOC102235526 LOC102235526 LOC102232366 LOC102232366 cacng6 cacng6 LOC102238368 LOC102238368 LOC102236219 LOC102236219 LOC102217063 LOC102217063 LOC102225613 LOC102225613 LOC102233275 LOC102233275 M4AH59_XIPMA M4AH59_XIPMA RYR2 RYR2 LOC102232929 LOC102232929 LOC102237380 LOC102237380 ACTA1 ACTA1 LOC106700490 LOC106700490 LOC102237316 LOC102237316 slc9a7 slc9a7 LOC102221486 LOC102221486 LOC102236496 LOC102236496 LOC102234247 LOC102234247 LOC102227354 LOC102227354 LOC102234891 LOC102234891 LOC102232694 LOC102232694 LOC102228370 LOC102228370 LOC102225603 LOC102225603 LOC102236755 LOC102236755 M4AZF2_XIPMA M4AZF2_XIPMA COX1 COX1 COX2 COX2 COX3 COX3 CYTB CYTB UQCRFS1 UQCRFS1 LOC102217899 LOC102217899 LOC102234348 LOC102234348 ENSXMAP00000022043 ENSXMAP00000022043 ENSXMAP00000022225 ENSXMAP00000022225 LOC102233577 LOC102233577 LOC102238060 LOC102238060 LOC102237993 LOC102237993 Cacna2d4 Cacna2d4 LOC102222361 LOC102222361 LOC102224746 LOC102224746 CACNG2 CACNG2 CACNG5 CACNG5 LOC102225253 LOC102225253 slc8a3 slc8a3 atp2a3 atp2a3 LOC102228666 LOC102228666 LOC102224098 LOC102224098 LOC102236876 LOC102236876 ENSXMAP00000029696 ENSXMAP00000029696 LOC102219987 LOC102219987 LOC102231524 LOC102231524 LOC102220955 LOC102220955 LOC102217146 LOC102217146 LOC102223620 LOC102223620 atp1b4 atp1b4 LOC102226926 LOC102226926 cacng4 cacng4 LOC102232874 LOC102232874 ENSXMAP00000033306 ENSXMAP00000033306 LOC102223705 LOC102223705 LOC102223124 LOC102223124 slc9a1 slc9a1 CACNA2D3 CACNA2D3 LOC102229958 LOC102229958 cacnb2 cacnb2 LOC102227162 LOC102227162 MYL2-2 MYL2-2 LOC102218310 LOC102218310 LOC102217201 LOC102217201 LOC102228942 LOC102228942 slc8a1 slc8a1 LOC102221222 LOC102221222 COX7A2 COX7A2 LOC102230019 LOC102230019 LOC102238122 LOC102238122 LOC102219286 LOC102219286 LOC102216805 LOC102216805 COX5A COX5A LOC102234042 LOC102234042 cacna1s cacna1s LOC102231613 LOC102231613 LOC102232954 LOC102232954 LOC102227037 LOC102227037 cacnb4 cacnb4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
cacng3Calcium voltage-gated channel auxiliary subunit gamma 3. (317 aa)
LOC102237830Uncharacterized protein; Belongs to the tropomyosin family. (249 aa)
LOC102227478Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1. (286 aa)
LOC102229283Uncharacterized protein. (126 aa)
LOC102218802Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
LOC102221483Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
LOC102224767Ubiquinol-cytochrome c reductase core protein 2a. (459 aa)
LOC102219848Ubiquinol-cytochrome c reductase, complex III subunit X. (62 aa)
LOC102219450Ubiquinol-cytochrome c reductase core protein 1. (478 aa)
LOC102233799Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (410 aa)
LOC102221223Cytochrome c oxidase subunit 4I1. (169 aa)
tpm4Tropomyosin 4a; Belongs to the tropomyosin family. (284 aa)
LOC102226217Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
LOC102237528Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (98 aa)
MYL2Myosin, light chain 2b, regulatory, cardiac, slow. (189 aa)
LOC102226226Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (415 aa)
LOC102233017Calcium channel, voltage-dependent, beta 4b subunit. (510 aa)
LOC102220863Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
LOC102222505Sodium/potassium-transporting ATPase subunit alpha. (1010 aa)
LOC102229576Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1933 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (230 aa)
LOC102220985Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (317 aa)
LOC102233599Uncharacterized protein. (377 aa)
LOC102218145Sodium/potassium-transporting ATPase subunit alpha. (1025 aa)
LOC102221627Ubiquinol-cytochrome c reductase, complex III subunit VII. (82 aa)
ACTC1Zgc:86709. (377 aa)
LOC102228764Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (341 aa)
LOC102230071Uncharacterized protein. (282 aa)
LOC102221379Calcium channel, voltage-dependent, beta 3b. (265 aa)
LOC102231053Sodium/potassium-transporting ATPase subunit alpha. (1009 aa)
LOC102235526Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (291 aa)
LOC102232366Calcium channel, voltage-dependent, alpha 2/delta subunit 1a. (1079 aa)
cacng6Calcium channel, voltage-dependent, gamma subunit 6b. (266 aa)
LOC102238368Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (351 aa)
LOC102236219Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (86 aa)
LOC102217063Sodium/potassium-transporting ATPase subunit alpha. (1023 aa)
LOC102225613Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (679 aa)
LOC102233275Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1062 aa)
M4AH59_XIPMACalcium channel, voltage dependent, alpha2/delta subunit 3. (450 aa)
RYR2Uncharacterized protein. (4870 aa)
LOC102232929Cytochrome c-1. (307 aa)
LOC102237380Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (228 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
LOC106700490Uncharacterized protein. (70 aa)
LOC102237316Cytochrome c oxidase subunit 7A2 like. (115 aa)
slc9a7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (681 aa)
LOC102221486Cytochrome c oxidase subunit 4I2. (178 aa)
LOC102236496Sodium/potassium-transporting ATPase subunit alpha. (1022 aa)
LOC102234247Uncharacterized protein. (241 aa)
LOC102227354Calcium channel, voltage-dependent, alpha 2/delta subunit 2b. (1102 aa)
LOC102234891Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (926 aa)
LOC102232694Myosin heavy chain 7-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1949 aa)
LOC102228370Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
LOC102225603Cytochrome c oxidase subunit 6C. (76 aa)
LOC102236755Cytochrome c oxidase subunit 7C. (63 aa)
M4AZF2_XIPMAUncharacterized protein. (217 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (518 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (230 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (240 aa)
LOC102217899Myosin, light chain 13. (188 aa)
LOC102234348Troponin T2d, cardiac. (263 aa)
ENSXMAP00000022043VWFA domain-containing protein. (439 aa)
ENSXMAP00000022225Cytochrome c oxidase subunit 5B2. (132 aa)
LOC102233577Solute carrier family 8 member 4b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (952 aa)
LOC102238060Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
LOC102237993Uncharacterized protein. (87 aa)
Cacna2d4VGCC_alpha2 domain-containing protein. (187 aa)
LOC102222361Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1041 aa)
LOC102224746Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (294 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
CACNG5Calcium channel, voltage-dependent, gamma subunit 5a. (277 aa)
LOC102225253Ubiquinol-cytochrome c reductase, complex III subunit XI. (60 aa)
slc8a3Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (925 aa)
atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1004 aa)
LOC102228666Calcium channel, voltage-dependent, gamma subunit 3a. (334 aa)
LOC102224098Solute carrier family 8 member 2b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1052 aa)
LOC102236876Cytochrome c oxidase subunit 7A1. (81 aa)
ENSXMAP00000029696Uncharacterized protein. (273 aa)
LOC102219987Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
LOC102231524Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (320 aa)
LOC102220955Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (363 aa)
LOC102217146Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
LOC102223620Calcium channel, voltage-dependent, alpha 2/delta subunit 2a. (1108 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (338 aa)
LOC102226926Calcium channel, voltage-dependent, gamma subunit 6a. (287 aa)
cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (333 aa)
LOC102232874Calcium channel, voltage-dependent, beta 3a. (567 aa)
ENSXMAP00000033306Asp-B-Hydro_N domain-containing protein. (177 aa)
LOC102223705Calcium channel, voltage-dependent, gamma subunit 8b. (413 aa)
LOC102223124Troponin T type 2b (cardiac). (232 aa)
slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (788 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1100 aa)
LOC102229958Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
cacnb2Calcium channel, voltage-dependent, beta 2a. (697 aa)
LOC102227162Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1036 aa)
MYL2-2Myosin light chain 2. (195 aa)
LOC102218310Tropomyosin 2 (beta); Belongs to the tropomyosin family. (284 aa)
LOC102217201Cytochrome c oxidase subunit 6A1; Belongs to the cytochrome c oxidase subunit 6A family. (136 aa)
LOC102228942Troponin C type 1b (slow). (243 aa)
slc8a1Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (960 aa)
LOC102221222Calcium channel, voltage-dependent, gamma subunit 8a. (451 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (85 aa)
LOC102230019Slow myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
LOC102238122Solute carrier family 8 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (946 aa)
LOC102219286Uncharacterized protein. (141 aa)
LOC102216805Solute carrier family 8 member 1a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (957 aa)
COX5ACytochrome c oxidase subunit 5Ab. (141 aa)
LOC102234042Cytochrome c oxidase subunit 6A, mitochondrial. (101 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1798 aa)
LOC102231613Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (300 aa)
LOC102232954Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1978 aa)
LOC102227037Calcium channel, voltage-dependent, gamma subunit 5b. (276 aa)
cacnb4Calcium channel, voltage-dependent, beta 4a subunit. (519 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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