STRINGSTRING
LOC102225395 LOC102225395 NBL1 NBL1 LOC102223402 LOC102223402 zfyve9 zfyve9 LOC102216881 LOC102216881 e2f4 e2f4 myc myc LOC102217256 LOC102217256 LOC102218062 LOC102218062 LOC102223630 LOC102223630 rock1 rock1 rgma rgma LOC102223216 LOC102223216 smad6 smad6 smad3 smad3 LOC102235592 LOC102235592 grem2 grem2 ppp2r1b ppp2r1b LOC102229551 LOC102229551 TGFB3 TGFB3 LOC102234531 LOC102234531 LOC102224322 LOC102224322 LOC102230576 LOC102230576 rps6kb2 rps6kb2 LOC102228719 LOC102228719 cdkn2b cdkn2b LOC102227173 LOC102227173 mapk1 mapk1 chrd chrd skp1 skp1 ppp2ca ppp2ca bmp2 bmp2 smad9 smad9 LOC102217508 LOC102217508 LOC102223777 LOC102223777 LOC102226082 LOC102226082 acvr2a acvr2a LOC102237610 LOC102237610 ACVR1C ACVR1C acvr1 acvr1 tfdp1 tfdp1 gdf5 gdf5 LOC102233636 LOC102233636 LOC102230588 LOC102230588 thbs1 thbs1 TGFBR2 TGFBR2 LOC102231897 LOC102231897 rbl1 rbl1 LOC102235711 LOC102235711 tgfb3 tgfb3 nodal nodal LOC102220374 LOC102220374 THSD4 THSD4 LOC102222710 LOC102222710 sp1 sp1 LOC102237495 LOC102237495 LOC102234393 LOC102234393 LOC102229174 LOC102229174 LOC102233286 LOC102233286 LOC102233813 LOC102233813 GREM1 GREM1 LOC102225902 LOC102225902 neo1 neo1 pitx2 pitx2 bmpr1a bmpr1a LOC102221134 LOC102221134 ENSXMAP00000021726 ENSXMAP00000021726 LOC102225527 LOC102225527 LOC102227900 LOC102227900 LOC102223904 LOC102223904 LOC102238111 LOC102238111 SMURF2 SMURF2 bmpr1b bmpr1b bmp5 bmp5 rgmb rgmb fst fst LOC102216886 LOC102216886 Grem1 Grem1 LOC102237032 LOC102237032 ACVR1B ACVR1B rbx1 rbx1 LOC102231514 LOC102231514 ppp2cb ppp2cb LOC102231253 LOC102231253 SMAD4 SMAD4 LOC102223036 LOC102223036 ENSXMAP00000032374 ENSXMAP00000032374 Cul1 Cul1 hamp hamp smurf1 smurf1 LOC102233859 LOC102233859 LOC102235802 LOC102235802 INHBC INHBC LOC102218621 LOC102218621 LOC102222883 LOC102222883 LOC102226015 LOC102226015 LOC102233685 LOC102233685 LOC102233635 LOC102233635 dcn dcn smad7 smad7 bambi bambi bmp4 bmp4 bmp8a bmp8a ENSXMAP00000039114 ENSXMAP00000039114 gdf6 gdf6 INHBB INHBB LOC102222719 LOC102222719 LOC102236735 LOC102236735 SMAD3 SMAD3 ENSXMAP00000041178 ENSXMAP00000041178 LOC102225256 LOC102225256
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102225395Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
NBL1NBL1, DAN family BMP antagonist. (197 aa)
LOC102223402Anti-dorsalizing morphogenic protein. (372 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1167 aa)
LOC102216881Transforming growth factor beta; Belongs to the TGF-beta family. (394 aa)
e2f4E2F transcription factor 4. (389 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (432 aa)
LOC102217256Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
LOC102218062Inhibin subunit beta B. (393 aa)
LOC102223630Mothers against decapentaplegic homolog. (507 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1380 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (449 aa)
LOC102223216Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
smad6Mothers against decapentaplegic homolog. (492 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
LOC102235592E1A binding protein p300 b. (2751 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (589 aa)
LOC102229551BHLH domain-containing protein. (357 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (407 aa)
LOC102234531Uncharacterized protein. (193 aa)
LOC102224322Mothers against decapentaplegic homolog. (467 aa)
LOC102230576CREB binding protein b. (2446 aa)
rps6kb2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
LOC102228719Mothers against decapentaplegic homolog. (503 aa)
cdkn2bCyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (124 aa)
LOC102227173Bone morphogenetic protein 6. (428 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
chrdChordin; Belongs to the chordin family. (949 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
bmp2Bone morphogenetic protein 2b. (416 aa)
smad9Mothers against decapentaplegic homolog. (467 aa)
LOC102217508Uncharacterized protein. (87 aa)
LOC102223777Serine/threonine-protein phosphatase. (309 aa)
LOC102226082E1A binding protein p300 a. (2737 aa)
acvr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
LOC102237610Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (683 aa)
tfdp1Transcription factor. (410 aa)
gdf5Growth differentiation factor 5. (524 aa)
LOC102233636RGM domain family, member D. (465 aa)
LOC102230588Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1144 aa)
thbs1Thrombospondin 1a. (1172 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (539 aa)
LOC102231897TGF_BETA_2 domain-containing protein. (384 aa)
rbl1Retinoblastoma-like 1 (p107). (1055 aa)
LOC102235711Left-right determination factor. (361 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
nodalNodal-related 2. (378 aa)
LOC102220374Myelocytomatosis oncogene homolog. (355 aa)
THSD4Thrombospondin type 1 domain containing 4. (966 aa)
LOC102222710Ras homolog gene family, member Ab. (193 aa)
sp1Sp1 transcription factor. (658 aa)
LOC102237495Southpaw. (408 aa)
LOC102234393Inhibitor of DNA binding 3. (116 aa)
LOC102229174Uncharacterized protein. (193 aa)
LOC102233286Noggin; Belongs to the noggin family. (211 aa)
LOC102233813Noggin; Belongs to the noggin family. (222 aa)
GREM1Gremlin. (182 aa)
LOC102225902Noggin; Belongs to the noggin family. (211 aa)
neo1Neogenin 1b. (1461 aa)
pitx2Homeobox protein. (312 aa)
bmpr1aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (541 aa)
LOC102221134CREB binding protein a. (2460 aa)
ENSXMAP00000021726FYVE domain-containing protein. (71 aa)
LOC102225527Uncharacterized protein. (193 aa)
LOC102227900Mothers against decapentaplegic homolog. (472 aa)
LOC102223904Inhibitor of DNA binding 4. (154 aa)
LOC102238111Homeobox domain-containing protein. (535 aa)
SMURF2E3 ubiquitin-protein ligase. (776 aa)
bmpr1bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
bmp5Bone morphogenetic protein 5. (460 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (472 aa)
fstFollistatin a. (351 aa)
LOC102216886Zinc finger, FYVE domain containing 16. (1395 aa)
Grem1Gremlin 1a, DAN family BMP antagonist. (162 aa)
LOC102237032Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (463 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (149 aa)
LOC102231514Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (598 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC102231253Tumor necrosis factor a (TNF superfamily, member 2). (245 aa)
SMAD4Mothers against decapentaplegic homolog. (512 aa)
LOC102223036Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
ENSXMAP00000032374TGF_BETA_2 domain-containing protein. (129 aa)
Cul1Cullin 1b; Belongs to the cullin family. (332 aa)
hampUncharacterized protein. (89 aa)
smurf1E3 ubiquitin-protein ligase. (731 aa)
LOC102233859Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (498 aa)
LOC102235802TGFB-induced factor homeobox 1. (327 aa)
INHBCInhibin subunit beta C. (383 aa)
LOC102218621Fibromodulin a. (349 aa)
LOC102222883Thrombospondin 1b. (1169 aa)
LOC102226015Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (539 aa)
LOC102233685Uncharacterized protein. (193 aa)
LOC102233635Inhibitor of DNA binding 1, HLH protein. (127 aa)
dcnDecorin; May affect the rate of fibrils formation. (360 aa)
smad7Mothers against decapentaplegic homolog. (378 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
bmp4Bone morphogenetic protein 4. (399 aa)
bmp8aBone morphogenetic protein 8a. (431 aa)
ENSXMAP00000039114Bone morphogenetic protein 16. (511 aa)
gdf6Growth differentiation factor 6a. (418 aa)
INHBBInhibin subunit beta B. (394 aa)
LOC102222719Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (518 aa)
LOC102236735Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSXMAP00000041178E2F transcription factor 5. (149 aa)
LOC102225256Hemojuvelin BMP co-receptor. (518 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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