STRINGSTRING
tyk2 tyk2 LOC102219021 LOC102219021 fadd fadd atg16l1 atg16l1 LOC102234804 LOC102234804 LOC106700093 LOC106700093 itpr2 itpr2 nod1 nod1 LOC102226269 LOC102226269 LOC102229876 LOC102229876 LOC102217611 LOC102217611 LOC102236235 LOC102236235 LOC102217419 LOC102217419 nek7 nek7 tbk1 tbk1 LOC102221102 LOC102221102 LOC102228722 LOC102228722 LOC102222087 LOC102222087 LOC102230058 LOC102230058 pkn2 pkn2 M3ZPV8_XIPMA M3ZPV8_XIPMA ikbkg ikbkg LOC102216528 LOC102216528 LOC102234531 LOC102234531 LOC102233702 LOC102233702 mapk10 mapk10 RNF31 RNF31 mfn2 mfn2 LOC102229818 LOC102229818 LOC102227944 LOC102227944 map3k7 map3k7 dhx33 dhx33 rbck1 rbck1 LOC102232835 LOC102232835 mapk1 mapk1 PLCB2 PLCB2 LOC102236946 LOC102236946 LOC102217878 LOC102217878 LOC102219036 LOC102219036 vdac1 vdac1 LOC102220339 LOC102220339 itpr1 itpr1 LOC102218115 LOC102218115 LOC102218377 LOC102218377 nlrx1 nlrx1 LOC102219479 LOC102219479 nfkbia nfkbia BCL2L1 BCL2L1 LOC102223422 LOC102223422 LOC102223674 LOC102223674 LOC102218102 LOC102218102 LOC102226088 LOC102226088 LOC102237850 LOC102237850 birc2 birc2 LOC102237758 LOC102237758 LOC102219636 LOC102219636 LOC102218600 LOC102218600 LOC102217801 LOC102217801 traf6 traf6 atg12 atg12 casr casr pycard pycard LOC111608209 LOC111608209 LOC102230168 LOC102230168 LOC102232287 LOC102232287 card9 card9 VDAC2 VDAC2 trpm2 trpm2 gabarapl2 gabarapl2 LOC102233539 LOC102233539 LOC102222710 LOC102222710 ripk1 ripk1 DNM1L DNM1L LOC102219317 LOC102219317 mfn1 mfn1 tp53bp1 tp53bp1 traf3 traf3 LOC111605766 LOC111605766 LOC102220363 LOC102220363 sting1 sting1 LOC102233918 LOC102233918 LOC102229174 LOC102229174 M4AZD2_XIPMA M4AZD2_XIPMA jun jun Brcc3 Brcc3 LOC102230198 LOC102230198 LOC106700431 LOC106700431 trip6 trip6 LOC102231047 LOC102231047 atg5 atg5 bcl2l1 bcl2l1 LOC102225527 LOC102225527 LOC102220624 LOC102220624 LOC102217350 LOC102217350 LOC102237237 LOC102237237 LOC102223477 LOC102223477 antxr2 antxr2 mavs mavs LOC102227852 LOC102227852 LOC102228179 LOC102228179 nod2 nod2 ikbkb ikbkb LOC102229031 LOC102229031 irf9 irf9 LOC102229375 LOC102229375 LOC102219145 LOC102219145 il18 il18 LOC102237032 LOC102237032 LOC102238285 LOC102238285 mcu mcu sugt1 sugt1 LOC102228854 LOC102228854 panx1 panx1 LOC102231253 LOC102231253 LOC111608983 LOC111608983 LOC102217432 LOC102217432 tab2 tab2 LOC102224771 LOC102224771 LOC102233259 LOC102233259 irf7 irf7 LOC102233408 LOC102233408 LOC102230139 LOC102230139 sharpin sharpin bcl2 bcl2 LOC102233752 LOC102233752 tank tank mapk8 mapk8 myd88 myd88 erbin erbin LOC102234094 LOC102234094 tnfaip3 tnfaip3 LOC102233685 LOC102233685 LOC102224328 LOC102224328 gabarap gabarap LOC106699651 LOC106699651 LOC111608146 LOC111608146 txnip txnip jak1 jak1 CHUK CHUK ripk2 ripk2 LOC111609837 LOC111609837 LOC102231001 LOC102231001 irak4 irak4 tab1 tab1 LOC102226521-2 LOC102226521-2 LOC102225755 LOC102225755 LOC111610322 LOC111610322 LOC102236163 LOC102236163 tab3 tab3 LOC102217177 LOC102217177 prkcd prkcd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tyk2Tyrosine-protein kinase. (1155 aa)
LOC102219021Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (257 aa)
faddUncharacterized protein. (196 aa)
atg16l1ATG16 autophagy related 16-like 1 (S. cerevisiae). (603 aa)
LOC102234804Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (673 aa)
LOC106700093Uncharacterized protein. (262 aa)
itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (2636 aa)
nod1Nucleotide-binding oligomerization domain containing 1. (941 aa)
LOC102226269Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (482 aa)
LOC102229876Thioredoxin; Belongs to the thioredoxin family. (107 aa)
LOC102217611ANTXR cell adhesion molecule 1a. (625 aa)
LOC102236235Signal transducer and activator of transcription. (797 aa)
LOC102217419Inositol 1,4,5-trisphosphate receptor, type 1a. (2694 aa)
nek7NIMA-related kinase 7; Belongs to the protein kinase superfamily. (307 aa)
tbk1TANK-binding kinase 1. (721 aa)
LOC102221102Proline-serine-threonine phosphatase interacting protein 1a. (409 aa)
LOC102228722Inhibitor of nuclear factor kappa B kinase subunit epsilon. (735 aa)
LOC102222087Cathepsin Bb; Belongs to the peptidase C1 family. (330 aa)
LOC102230058ANTXR cell adhesion molecule 1b. (684 aa)
pkn2Protein kinase N2. (989 aa)
M3ZPV8_XIPMAFzo_mitofusin domain-containing protein. (371 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (583 aa)
LOC102216528Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (436 aa)
LOC102234531Uncharacterized protein. (193 aa)
LOC102233702Zgc:56235. (282 aa)
mapk10Mitogen-activated protein kinase. (401 aa)
RNF31Ring finger protein 31. (1116 aa)
mfn2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (758 aa)
LOC102229818Arrestin_C domain-containing protein. (379 aa)
LOC102227944TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (600 aa)
dhx33DEAH (Asp-Glu-Ala-His) box polypeptide 33. (681 aa)
rbck1RanBP-type and C3HC4-type zinc finger containing 1. (515 aa)
LOC102232835Cytochrome b-245, beta polypeptide (chronic granulomatous disease). (565 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (364 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1098 aa)
LOC102236946X-linked inhibitor of apoptosis. (401 aa)
LOC1022178781-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
LOC102219036Uncharacterized protein. (280 aa)
vdac1Voltage-dependent anion channel 1. (283 aa)
LOC102220339Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (493 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1b. (2671 aa)
LOC102218115Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (733 aa)
LOC102218377Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (724 aa)
nlrx1NLR family member X1. (956 aa)
LOC1022194791-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1204 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (386 aa)
BCL2L1BCL2 like 1. (219 aa)
LOC102223422Mitogen-activated protein kinase. (362 aa)
LOC102223674Mitogen-activated protein kinase. (361 aa)
LOC102218102Mitogen-activated protein kinase. (357 aa)
LOC102226088Component of inhibitor of nuclear factor kappa B kinase complex. (733 aa)
LOC102237850Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (509 aa)
birc2Baculoviral IAP repeat containing 2. (642 aa)
LOC102237758Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (695 aa)
LOC102219636V-rel avian reticuloendotheliosis viral oncogene homolog A. (629 aa)
LOC102218600Zgc:92606. (117 aa)
LOC102217801Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (301 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
atg12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (135 aa)
casrCalcium-sensing receptor. (940 aa)
pycardUncharacterized protein. (186 aa)
LOC111608209PYD and CARD domain containing. (201 aa)
LOC102230168ANTXR cell adhesion molecule 1d. (575 aa)
LOC102232287Protein kinase domain-containing protein. (549 aa)
card9CARD domain-containing protein. (535 aa)
VDAC2Voltage dependent anion channel 2. (283 aa)
trpm2Transient receptor potential cation channel, subfamily M, member 2. (1396 aa)
gabarapl2GABA(A) receptor-associated protein like 2. (116 aa)
LOC102233539Purinergic receptor P2X, ligand-gated ion channel, 7. (622 aa)
LOC102222710Ras homolog gene family, member Ab. (193 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (676 aa)
DNM1LDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (731 aa)
LOC102219317Heat shock protein 90, alpha (cytosolic), class B member 1. (723 aa)
mfn1Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (756 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1252 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (590 aa)
LOC111605766Uncharacterized protein; Belongs to the peptidase C14A family. (386 aa)
LOC102220363Uncharacterized protein; Belongs to the peptidase C14A family. (386 aa)
sting1Transmembrane protein 173. (398 aa)
LOC102233918Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
LOC102229174Uncharacterized protein. (193 aa)
M4AZD2_XIPMAUncharacterized protein. (485 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (329 aa)
Brcc3BRCA1/BRCA2-containing complex, subunit 3. (267 aa)
LOC102230198Protein kinase N1b. (961 aa)
LOC106700431Uncharacterized protein. (184 aa)
trip6Uncharacterized protein. (610 aa)
LOC102231047Mitogen-activated protein kinase. (360 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (326 aa)
bcl2l1BH4_2 domain-containing protein. (227 aa)
LOC102225527Uncharacterized protein. (193 aa)
LOC102220624Uncharacterized protein; Belongs to the peptidase C14A family. (401 aa)
LOC102217350TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (597 aa)
LOC102237237Mitogen-activated protein kinase. (420 aa)
LOC102223477Mitogen-activated protein kinase. (364 aa)
antxr2Anthrax toxin receptor; Belongs to the ATR family. (500 aa)
mavsCARD_2 domain-containing protein. (559 aa)
LOC102227852Transient receptor potential cation channel, subfamily M, member 2. (1259 aa)
LOC102228179Proline-serine-threonine phosphatase interacting protein 1b. (411 aa)
nod2Nucleotide-binding oligomerization domain containing 2. (973 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (743 aa)
LOC102229031Uncharacterized protein; Belongs to the peptidase C14A family. (268 aa)
irf9Interferon regulatory factor 9. (423 aa)
LOC102229375TRIF-NTD domain-containing protein. (563 aa)
LOC102219145Cytochrome b-245, alpha polypeptide. (194 aa)
il18Uncharacterized protein. (218 aa)
LOC102237032Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (511 aa)
LOC102238285Protein kinase N1a. (952 aa)
mcuMitochondrial calcium uniporter. (467 aa)
sugt1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (323 aa)
LOC102228854Interferon regulatory factor 3. (465 aa)
panx1Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (405 aa)
LOC102231253Tumor necrosis factor a (TNF superfamily, member 2). (245 aa)
LOC111608983Si:dkey-181m9.8. (478 aa)
LOC102217432Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (102 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (740 aa)
LOC102224771ANTXR cell adhesion molecule 1c. (560 aa)
LOC102233259C-X-C motif chemokine. (104 aa)
irf7Interferon regulatory factor 7. (479 aa)
LOC102233408TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (516 aa)
LOC102230139Thioredoxin; Belongs to the thioredoxin family. (108 aa)
sharpinSHANK-associated RH domain interacting protein. (435 aa)
bcl2BCL2 apoptosis regulator b. (229 aa)
LOC102233752Mitogen-activated protein kinase. (435 aa)
tankTRAF family member-associated NFKB activator. (338 aa)
mapk8Mitogen-activated protein kinase. (384 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
erbinErbb2 interacting protein. (1373 aa)
LOC102234094Mitogen-activated protein kinase. (457 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (825 aa)
LOC102233685Uncharacterized protein. (193 aa)
LOC102224328Anthrax toxin receptor; Belongs to the ATR family. (519 aa)
gabarapGABA(A) receptor-associated protein b. (122 aa)
LOC106699651Uncharacterized protein. (180 aa)
LOC111608146Uncharacterized protein. (1326 aa)
txnipThioredoxin interacting protein. (399 aa)
jak1Tyrosine-protein kinase. (1174 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (798 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (584 aa)
LOC111609837Uncharacterized protein. (184 aa)
LOC102231001Voltage-dependent anion channel 2. (306 aa)
irak4Interleukin-1 receptor-associated kinase 4. (462 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (494 aa)
LOC102226521-2Uncharacterized protein. (1334 aa)
LOC102225755Signal transducer and activator of transcription. (756 aa)
LOC111610322Interleukin-1. (247 aa)
LOC10223616314_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
tab3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (609 aa)
LOC102217177Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (99 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (683 aa)
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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