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| | CED56675.1 | Putative uncharacterized protein. (222 aa) |
| | CED56711.1 | Putative zinc-containing alcohol dehydrogenase. (332 aa) |
| | CED56727.1 | enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa) |
| | CED56759.1 | Putative zinc-containing alcohol dehydrogenase. (324 aa) |
| | CED56871.1 | Pyruvate formate lyase. (765 aa) |
| | CED56898.1 | 6-phosphogluconate dehydrogenase, NAD-binding. (292 aa) |
| | CED56910.1 | NAD-dependent formate dehydrogenase alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1383 aa) |
| | CED56922.1 | Putative ferredoxin. (387 aa) |
| | gcvP | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (955 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | CED57093.1 | Aminomethyltransferase. (372 aa) |
| | CED57094.1 | Putative uncharacterized MaoC domain protein. (227 aa) |
| | CED57139.1 | Putative thioesterase; Similar to Escherichia coli Esterase YdiI UniProt:P77781 (136 aa) fasta scores: E()=5.3e-23, 48.148% id in 135 aa. The CDS appears to be truncated at the N-terminus. (141 aa) |
| | pykA | Pyruvate kinase II; Belongs to the pyruvate kinase family. (481 aa) |
| | ppaC | Manganese-dependent inorganic pyrophosphatase. (306 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) |
| | CED57598.1 | Putative ferredoxin oxidoreductase. (343 aa) |
| | CED57837.1 | Putative uncharacterized dehydrogenase. (222 aa) |
| | CED70121.1 | Putative zinc-binding alcohol dehydrogenase. (326 aa) |
| | fadA | Fatty oxidation complex beta subunit, 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa) |
| | fadB | Fatty oxidation complex alpha subunit, enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (725 aa) |
| | glnA | Glutamine synthetase. (469 aa) |
| | frdD | Fumarate reductase complex, membrane anchor subunit D; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (120 aa) |
| | frdC | Fumarate reductase complex, membrane anchor subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (127 aa) |
| | frdB | Fumarate reductase complex, iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (247 aa) |
| | CED70361.1 | Fumarate reductase complex, flavoprotein subunit. (603 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (876 aa) |
| | CED70394.1 | Dihydrolipoyl dehydrogenase (dihydrolipoamide dehydrogenase). (488 aa) |
| | maeB | NADP-dependent malic enzyme. (415 aa) |
| | CED70433.1 | AMP-binding enzyme, putative long chain fatty acid Co-A ligase, acetyl-CoA synthetase. (609 aa) |
| | ilvI | Acetolactate synthase isozyme III large subunit. (573 aa) |
| | ilvH | Acetolactate synthase isozyme III small subunit. (164 aa) |
| | pykF | Pyruvate kinase; Belongs to the pyruvate kinase family. (470 aa) |
| | CED70440.1 | AMP-binding enzyme, putative long chain fatty acid Co-A ligase, acetyl-CoA synthetase. (515 aa) |
| | zapE | Putative ATPase; Reduces the stability of FtsZ polymers in the presence of ATP. (368 aa) |
| | CED70474.1 | Ubiquinol-cytochrome c reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (202 aa) |
| | petB | Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (422 aa) |
| | CED70476.1 | Ubiquinol--cytochrome c reductase, cytochrome C1. (245 aa) |
| | aceE | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | aceF | Dihydrolipoyllysine-residue acetyltransferase component of pyruvat dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (625 aa) |
| | lpdA | Dihydrolipoamide dehydrogenase. (476 aa) |
| | acnB | Aconitate hydratase 2 (citrate hydro-lyase 2); Belongs to the aconitase/IPM isomerase family. (862 aa) |
| | CED70603.1 | Putative AMP-binding acetyl-CoA synthetase. (558 aa) |
| | oadG | Oxaloacetate decarboxylase 1, subunit gamma; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (83 aa) |
| | CED70611.1 | Oxaloacetate decarboxylase 2, subunit alpha. (594 aa) |
| | CED70612.1 | Oxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa) |
| | CED70614.1 | Exported pepdidase, putative zinc protease. (950 aa) |
| | yeiG | Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa) |
| | adhC | Alcohol dehydrogenase class 3; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (382 aa) |
| | CED70720.1 | Sodium/dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (429 aa) |
| | adhC-2 | Alcohol dehydrogenase class 3; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (382 aa) |
| | CED70722.1 | HTH-type transcriptional regulator, LysR-family; Belongs to the LysR transcriptional regulatory family. (290 aa) |
| | tadA-2 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (173 aa) |
| | gltA | Citrate synthase; Belongs to the citrate synthase family. (429 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b556 subunit. (133 aa) |
| | sdhD | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB | Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (237 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component. (938 aa) |
| | sucB | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (403 aa) |
| | sucC | succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (720 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa) |
| | CED70900.1 | FAD dependent oxidoreductase. (418 aa) |
| | CED70901.1 | Putative O-methyltransferase. (359 aa) |
| | CED70902.1 | Putative lipoprotein. (191 aa) |
| | CED70903.1 | Putative uncharacterized protein. (242 aa) |
| | CED70904.1 | Putative membrane accosiated acyltransferase. (265 aa) |
| | CED70905.1 | Acyl carrier protein. (85 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (83 aa) |
| | CED70907.1 | Membrane protein. (186 aa) |
| | CED70908.1 | Putative uncharacterized AMP-binding enzyme. (455 aa) |
| | CED70909.1 | Putative uncharacterized protein. (124 aa) |
| | CED70910.1 | Putative glycosyl transferase. (563 aa) |
| | CED70912.1 | Putative thioesterase. (150 aa) |
| | CED70913.1 | Putative outer membrane protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (206 aa) |
| | CED70914.1 | Membrane protein. (778 aa) |
| | CED70915.1 | Putative lipoprotein. (209 aa) |
| | CED70916.1 | beta-ketoacyl-[ACP] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (396 aa) |
| | CED70917.1 | beta-hydroxydecanoyl-ACP dehydrase. (156 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase. (241 aa) |
| | fabF | 3-oxoacyl-[acyl-carrier-protein] synthase 2; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (411 aa) |
| | CED70926.1 | Putative lipoprotein. (409 aa) |
| | fabV | Putative reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (400 aa) |
| | adhE | Aldehyde-alcohol dehydrogenase; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (883 aa) |
| | CED71044.1 | Putatuve alcohol dehydrogenase. (326 aa) |
| | CED71063.1 | MaoC domain protein. (152 aa) |
| | ldhA | D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa) |
| | CED71215.1 | 6-phosphogluconate dehydrogenase. (298 aa) |
| | CED71252.1 | Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (508 aa) |
| | adhB | Alcohol dehydrogenase 2. (381 aa) |
| | fdhA | Formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (951 aa) |
| | fdhB | Formate dehydrogenase iron-sulfur subunit. (202 aa) |
| | fdnI | Formate dehydrogenase, cytochrome B556 subunit. (339 aa) |
| | fabA | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | gdhB | NAD-dependent glutamate dehydrogenase. (1611 aa) |
| | CED71487.1 | enoyl-CoA hydratase/isomerase. (268 aa) |
| | CED71499.1 | Phosphoenolpyruvate synthase. (294 aa) |
| | sfcA | NAD-dependent malic enzyme. (562 aa) |
| | pflB | Formate acetyltransferase 1. (758 aa) |
| | pflA | Pyruvate formate-lyase 1 activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (245 aa) |
| | fadH | 2,4-dienoyl-CoA reductase [NADPH]. (667 aa) |
| | CED71851.1 | Membrane associated acyltransferase. (622 aa) |
| | menE | O-succinylbenzoate-CoA ligase. (466 aa) |
| | menC | O-succinylbenzoate-CoA synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (324 aa) |
| | menB | Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (288 aa) |
| | menH | acyl-CoA thioester hydrolase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). (264 aa) |
| | menD | Menaquinone biosynthesis protein MenD; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (577 aa) |
| | menF | Menaquinone-specific isochorismate synthase; Catalyzes the conversion of chorismate to isochorismate. (440 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (294 aa) |
| | fabB | 3-ketoacyl-ACP synthase FabB; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa) |
| | fadD | long-chain-fatty-acid-CoA ligase. (560 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (277 aa) |
| | CED71898.1 | Putative hydrolytic enzyme, alpha/beta hydrolase. (265 aa) |
| | CED71899.1 | Putative uncharacterized protein. (289 aa) |
| | CED71900.1 | Putative beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (380 aa) |
| | CED71901.1 | Putative uncharacterized protein. (89 aa) |
| | CED71902.1 | ABC-2 type transporter, ATP-binding protein. (388 aa) |
| | CED71903.1 | ABC transporter, ATP-binding protein. (307 aa) |
| | CED71904.1 | Membrane protein. (338 aa) |
| | CED71905.1 | Putative DNA binding protein. (137 aa) |
| | CED71906.1 | Putative 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III. (382 aa) |
| | CED71907.1 | Membrane protein. (304 aa) |
| | CED71921.1 | Putative TatD-related deoxyribonuclease. (256 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (336 aa) |
| | pabC | Aminodeoxychorismate lyase. (269 aa) |
| | fabF-2 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa) |
| | acpV | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | fabG-2 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (245 aa) |
| | fabD | Malonyl CoA-acyl carrier protein transacylase. (307 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (317 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (342 aa) |
| | CED71933.1 | Putative uncharacterized protein. (173 aa) |
| | icd | Isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (742 aa) |
| | fadJ | Fatty acid oxidation complex alpha subunit [includes: enoyl-co hydratase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (698 aa) |
| | fadI | 3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (442 aa) |
| | fadE | Acyl-coenzyme A dehydrogenase. (815 aa) |
| | accA | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | aceA | Isocitrate lyase. (442 aa) |
| | aceB | Malate synthase A; Belongs to the malate synthase family. (534 aa) |
| | fdx-2 | Ferredoxin. (84 aa) |
| | gltB | Glutamate synthase, large subunit. (1515 aa) |
| | CED72267.1 | Glutamate synthase, small subunit. (490 aa) |
| | glsA | Glutaminase; Belongs to the glutaminase family. (306 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (515 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (363 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (471 aa) |
| | leuD | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (200 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (311 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (302 aa) |
| | acs | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (649 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (262 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (541 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (494 aa) |
| | ilvG | Acetolactate synthase isozyme II large subunit. (548 aa) |
| | ilvM | Acetolactate synthase small subunit. (81 aa) |
| | ilvD | Dihydroxy-acid dehydratase; The CDS appears to have a deletion of 130 amino acid residues after codon 297 in comparison to orthologues; Belongs to the IlvD/Edd family. (618 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (510 aa) |
| | atpC | ATP synthase epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (140 aa) |
| | atpD | ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (467 aa) |
| | atpG | ATP synthase gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (288 aa) |
| | atpA | ATP synthase alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa) |
| | atpH | ATP synthase delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (177 aa) |
| | atpF | ATP synthase B chain; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (154 aa) |
| | atpE | ATP synthase c chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (85 aa) |
| | atpB | ATP synthase A chain; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (265 aa) |
| | atpI | ATP synthase protein I. (129 aa) |
