STRINGSTRING
CED56712.1 CED56712.1 CED56725.1 CED56725.1 manA manA gbpA gbpA CED56964.1 CED56964.1 ebgC ebgC ebgA ebgA ebgR ebgR galE galE galT galT galK galK galM galM CED57006.1 CED57006.1 CED57007.1 CED57007.1 CED57009.1 CED57009.1 CED57017.1 CED57017.1 CED57018.1 CED57018.1 CED57019.1 CED57019.1 manA-2 manA-2 CED57021.1 CED57021.1 CED57023.1 CED57023.1 CED57024.1 CED57024.1 tktA tktA talB talB zwf zwf pgl pgl gnd gnd anmK anmK nagZ nagZ treR treR treB treB treA treA nagE nagE fruA fruA fruK fruK fruB fruB fruR fruR scrK scrK CED57707.1 CED57707.1 CED57708.1 CED57708.1 CED57709.1 CED57709.1 CED57768.1 CED57768.1 CED57769.1 CED57769.1 chb chb CED70127.1 CED70127.1 CED70136.1 CED70136.1 eda eda CED70324.1 CED70324.1 glmS glmS gap gap mtlR mtlR mtlD mtlD mtlA mtlA nagB nagB pfkA pfkA rpe rpe cytR cytR CED70541.1 CED70541.1 chbP chbP exoI exoI CED70544.1 CED70544.1 CED70545.1 CED70545.1 glmM glmM deoC deoC deoA deoA deoB deoB prs prs nagC nagC nagA nagA nagE-2 nagE-2 pgm pgm hexR hexR yeaD yeaD gap-2 gap-2 CED71069.1 CED71069.1 CED71140.1 CED71140.1 murQ murQ rbsR rbsR rbsK rbsK rbsB rbsB rbsC rbsC rbsA rbsA rbsD rbsD nagK nagK CED71336.1 CED71336.1 CED71488.1 CED71488.1 CED71489.1 CED71489.1 purR purR chiA chiA torT torT pdxB pdxB ptsG ptsG ptsH ptsH ptsI ptsI crr crr cutC cutC eno eno rpiA rpiA fbaA fbaA pgk pgk epd epd tktA-2 tktA-2 galU galU pgi pgi fbp fbp glpX glpX tpiA tpiA gpmI gpmI CED72526.1 CED72526.1 glmU glmU
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CED56712.1Putative exported protein. (294 aa)
CED56725.1Putative oxidoreductase. (304 aa)
manAMannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (401 aa)
gbpAGlcNAc-binding protein A; Probably interacts with GlcNAc residues. May promote attachment to both epithelial cell surfaces and chitin. Belongs to the GbpA family. (491 aa)
CED56964.1Alpha-galactosidase. (578 aa)
ebgCBeta-galactosidase, subunit beta. (150 aa)
ebgABeta-galactosidase, subunit alpha. (1033 aa)
ebgRHTH-type transcriptional regulator EbgR. (331 aa)
galEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (336 aa)
galTGalactose-1-phosphate uridylyltransferase. (349 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (386 aa)
galMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (352 aa)
CED57006.1HTH-type transcriptional regulator, LacI family. (332 aa)
CED57007.1Putative tRNA-binding protein. (110 aa)
CED57009.1Sodium/proton-dependent alanine carrier protein. (500 aa)
CED57017.1PTS system, IIC component. (623 aa)
CED57018.1PTS system, IIB component. (99 aa)
CED57019.1PTS system, IIA component. (261 aa)
manA-2Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. (399 aa)
CED57021.1PTS system, IIBC component. (633 aa)
CED57023.1PTS system, permease-specific phosphorylation site EIIA component. (143 aa)
CED57024.1PTS system, fructose-like permease IIC component. (466 aa)
tktATransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
talBTransaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (500 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (238 aa)
gnd6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (367 aa)
nagZBeta-hexosaminidase (beta-N-acetylhexosaminidase); Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (331 aa)
treRHTH-type transcriptional regulator TreR (trehalose operon repressor). (314 aa)
treBPTS system, trehalose-specific EIIBC component. (474 aa)
treATrehalose-6-phosphate hydrolase. (556 aa)
nagEPTS system permease for N-acetylglucosamine and glucose. (487 aa)
fruAPTS system, fructose-specific IIBC component. (580 aa)
fruK1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (327 aa)
fruBPTS system, fructose-specific IIA/FPR component. (378 aa)
fruRFructose repressor. (325 aa)
scrKFructokinase. (308 aa)
CED57707.1PTS system, sucrose-specific EIIBC component. (457 aa)
CED57708.1Glycosyl hydrolase, Family 32; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (486 aa)
CED57709.1Transcriptional regulator, LacI family. (330 aa)
CED57768.1Putative carbohydrate kinase, pfkB family. (312 aa)
CED57769.1Gluconate permease. (207 aa)
chbN,N'-diacetylchitobiase (chitobiase). (881 aa)
CED70127.16-phospho-beta-glucosidase; Belongs to the glycosyl hydrolase 1 family. (462 aa)
CED70136.1Putative beta-N-acetylhexosaminidase. (815 aa)
edaKHG/KDPG aldolase. (211 aa)
CED70324.1UDP-glucose 6-dehydrogenase. (388 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa)
gapGlyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
mtlRMannitol operon repressor (mannitol repressor protein). (176 aa)
mtlDMannitol-1-phosphate 5-dehydrogenase. (382 aa)
mtlAPTS system, mannitol-specific EIICBA component. (650 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (266 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
cytRHTH-type transcriptional repressor CytR. (335 aa)
CED70541.1Phosphoglucomutase/phosphomannomutase. (470 aa)
chbPChitobiose phosphorylase (glycosyl transferase). (801 aa)
exoIBeta-hexosaminidase (beta-N-acetylglucosaminidase). (634 aa)
CED70544.1Glucosamine kinase. (291 aa)
CED70545.1Putative endochitinase. (572 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily. (258 aa)
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (443 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (406 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (332 aa)
nagCN-acetylglucosamine repressor. (404 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase. (378 aa)
nagE-2PTS permease for N-acetylglucosamine and glucose. (496 aa)
pgmPhosphoglucomutase. (548 aa)
hexRHTH-type transcriptional regulator HexR. (284 aa)
yeaDPutative aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (291 aa)
gap-2Glyceraldehydes-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
CED71069.1Chitodextrinase. (1055 aa)
CED71140.1Putative phosphomannomutase. (568 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. (298 aa)
rbsRRibose operon repressor. (337 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa)
rbsBD-ribose-binding periplasmic protein precursor RbsB. (292 aa)
rbsCRibose transport system permease protein RbsC; Belongs to the binding-protein-dependent transport system permease family. (323 aa)
rbsARibose transport ATP-binding protein RbsA; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (504 aa)
rbsDRibose transport protein RbsD; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. (139 aa)
nagKN-acetyl-d-glucosamine kinase; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. (303 aa)
CED71336.1Chitinase. (569 aa)
CED71488.1Putative cell wall lytic enzyme. (143 aa)
CED71489.1Putative sucrose-6F-phosphate phosphohydrolase. (252 aa)
purRHTH-type transcriptional repressor PurR (purine nucleotide synthesis repressor); Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. (337 aa)
chiAChitinase. (845 aa)
torTPeriplasmic solute binding receptor protein. (331 aa)
pdxBErythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (376 aa)
ptsGPTS system, glucose-specific EIIBC component [includes: glucose permease IIC component; glucose-specific phosphotransferase enzyme II component]. (476 aa)
ptsHPhosphocarrier protein Hpr, histidine-containing protein (PTS system). (85 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase enzyme I (PTS system); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (574 aa)
crrGlucose-specific phosphotransferase enzyme IIA component (PTS system). (169 aa)
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (247 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa)
rpiARibose-5-phosphate isomerase A (phosphoriboisomerase A); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (218 aa)
fbaAFructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (358 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa)
epdD-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (339 aa)
tktA-2Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa)
galUUTP-glucose-1-phosphate uridylyltransferase. (289 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (550 aa)
fbpFructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family. (336 aa)
glpXFructose-1,6-bisphosphatase class II GlpX. (335 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (516 aa)
CED72526.1UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (335 aa)
glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (453 aa)
Your Current Organism:
Aliivibrio wodanis
NCBI taxonomy Id: 80852
Other names: A. wodanis, ATCC BAA-104, Aliivibrio wodanis (Lunder et al. 2000) Urbanczyk et al. 2007, DSM 22225, LMG 24053, LMG:24053, NCIMB 13582, Vibrio wodanis, Vibrio wodanis Lunder et al. 2000, strain NVI 88/441
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