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| | CED71222.1 | Carbon starvation protein. (488 aa) |
| | sbcD | Nuclease sbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (414 aa) |
| | CED71261.1 | ATP binding protein. (430 aa) |
| | CED71286.1 | DNA ligase. (284 aa) |
| | uspE | Universal stress protein E. (315 aa) |
| | uup | ABC transporter ATP-binding protein. (637 aa) |
| | CED71501.1 | Putative uncharacterized protein; Belongs to the UPF0234 family. (160 aa) |
| | CED71565.1 | SMC protein. (391 aa) |
| | sbcB | Exodeoxyribonuclease I. (474 aa) |
| | CED71654.1 | Putative uncharacterized protein. (128 aa) |
| | xthA | Exodeoxyribonuclease III. (268 aa) |
| | CED71807.1 | Helicase IV. (687 aa) |
| | uvrC | UvrABC system protein C (excinuclease ABC subunit C); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (608 aa) |
| | polB | DNA polymerase. (789 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa) |
| | CED71896.1 | Putative ATP-dependent helicase. (653 aa) |
| | clpA | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (751 aa) |
| | CED71962.1 | Putative sporulation protein. (505 aa) |
| | CED71981.1 | UPF0304 protein; Belongs to the UPF0304 family. (166 aa) |
| | ligA | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (668 aa) |
| | CED72093.1 | Putative lipoprotein. (110 aa) |
| | bcp | Putative peroxiredoxin Bcp. (125 aa) |
| | dnaQ | DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (242 aa) |
| | phoR | Sensor protein. (432 aa) |
| | recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (555 aa) |
| | CED72181.1 | NUDIX hydrolase; Belongs to the Nudix hydrolase family. (130 aa) |
| | recO | DNA repair protein RecO (recombination protein O); Involved in DNA repair and RecF pathway recombination. (238 aa) |
| | CED72242.1 | Putative uncharacterized protein. (67 aa) |
| | CED72250.1 | Putative exported protein. (231 aa) |
| | ung | uracil-DNA glycosylase (UDG); Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (222 aa) |
| | nfo | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (282 aa) |
| | mutH | DNA mismatch repair protein MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family. (222 aa) |
| | recJ | single-stranded-DNA-specific exonuclease RecJ. (579 aa) |
| | mutY | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (350 aa) |
| | CED72324.1 | Probable Fe(2+) trafficking protein; Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes. (90 aa) |
| | CED72343.1 | Putative uncharacterized protein, BolA family; Belongs to the BolA/IbaG family. (85 aa) |
| | CED72344.1 | Putative uncharacterized protein. (106 aa) |
| | ssb | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (181 aa) |
| | uvrA | UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (943 aa) |
| | msrA | Peptide methionine sulfoxide reductase MSRA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (194 aa) |
| | CED72397.1 | Putative uncharacterized protein. (69 aa) |
| | CED72408.1 | Signaling protein. (755 aa) |
| | CED72527.1 | Putative uncharacterized protein. (317 aa) |
| | CED72531.1 | Putative exonuclease. (213 aa) |
| | lexA | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (206 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | hslR | Heat shock protein 15; Belongs to the HSP15 family. (133 aa) |
| | gor | Glutathione reductase. (451 aa) |
| | rep | ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (671 aa) |
| | CED56840.1 | DNA-3-methyladenine glycosylase I. (242 aa) |
| | CED56830.1 | Putative uncharacterized protein, DJ-1/PfpI family. (229 aa) |
| | CED70877.1 | Putative uncharacterized protein. (251 aa) |
| | CED70862.1 | Putative competence protein ComEA. (101 aa) |
| | lon | ATP-dependent protease LA; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (783 aa) |
| | CED70809.1 | Putative uncharacterized protein; Belongs to the UPF0250 family. (89 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (355 aa) |
| | thiJ | Protein ThiJ. (196 aa) |
| | recD | Exodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...] (672 aa) |
| | recB | Exodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...] (1208 aa) |
| | recC | Exodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...] (1139 aa) |
| | CED70653.1 | Putative uncharacterized protein, YebG family. (96 aa) |
| | recA | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (348 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (855 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa) |
| | mutT | Mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase); Belongs to the Nudix hydrolase family. (132 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (733 aa) |
| | dam | DNA adenine methylase. (276 aa) |
| | CED70395.1 | Hybrid peroxiredoxin (thioredoxin reductase). (242 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (679 aa) |
| | mutM | DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (271 aa) |
| | CED70204.1 | Phosphate-starvation-inducible E; Belongs to the PsiE family. (142 aa) |
| | CED70188.1 | Putative lipoprotein. (340 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (934 aa) |
| | recQ-2 | ATP-dependent DNA helicase RecQ. (611 aa) |
| | uvrD | DNA helicase II UvrD. (734 aa) |
| | CED70120.1 | Putative inner membrane protein. (144 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (359 aa) |
| | recQ | Putative ATP-dependent DNA helicase. (639 aa) |
| | CED57729.1 | Signalling protein. (737 aa) |
| | ogt | methylguanine-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (157 aa) |
| | vasS-1 | Putative type VI secretion protein VasS-1. (140 aa) |
| | CED57544.1 | Ferric siderophore transport protein, utilization protein. (263 aa) |
| | CED57538.1 | Putative exported protein. (148 aa) |
| | tag | DNA-3-methyladenine glycosylase I. (192 aa) |
| | CED57468.1 | Putative uncharacterized protein. (314 aa) |
| | CED57353.1 | Putative uncharacterized protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (170 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1151 aa) |
| | CED57062.1 | Putative uncharacterized protein. (542 aa) |
| | deaD | Cold-shock DEAD box protein A (ATP-independent RNA helicase); DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (643 aa) |
| | CED57026.1 | Mechanosensitive ion channel. (421 aa) |
| | CED56984.1 | Membrane protein. (232 aa) |
| | CED56863.1 | Putative uncharacterized protein. (619 aa) |
| | CED70942.1 | Putative ATP-dependent helicase. (732 aa) |
| | CED70943.1 | Putative uncharacterized protein. (370 aa) |
| | trxB | Thioredoxin reductase. (321 aa) |
| | sodB | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (194 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (211 aa) |
| | uvrB | UvrABS system protein B (excinuclease ABC subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the [...] (676 aa) |
| | CED71020.1 | Putative uncharacterized protein. (321 aa) |
| | ruvC | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (173 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (207 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (337 aa) |
| | CED71086.1 | Putative uncharacterized protein. (70 aa) |
| | CED71108.1 | Putative lipoprotein. (133 aa) |
| | CED71158.1 | Membrane protein. (214 aa) |
| | CED71210.1 | Putative lipoprotein. (129 aa) |
