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| | LOC101155409 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (358 aa) |
| | aox1 | Aldehyde oxidase beta. (1333 aa) |
| | ubiad1 | UbiA prenyltransferase domain containing 1. (405 aa) |
| | LOC100125474 | Hydroxysteroid (11-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (407 aa) |
| | cbr1 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa) |
| | LOC101172907 | Zgc:172315; Belongs to the UDP-glycosyltransferase family. (549 aa) |
| | LOC101160538 | Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (526 aa) |
| | faxdc2 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. (342 aa) |
| | LOC101163971 | Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | coq2 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (375 aa) |
| | LOC101163759 | Cytochrome P450, family 26, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (525 aa) |
| | LOC105356506 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (366 aa) |
| | LOC101168135 | Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family. (285 aa) |
| | cyp17a2 | Cytochrome P450 family 17 polypeptide 2; Belongs to the cytochrome P450 family. (521 aa) |
| | LOC101175316 | Aldo_ket_red domain-containing protein. (326 aa) |
| | FBXO43 | F-box protein 43. (588 aa) |
| | Rgs22 | RGS domain-containing protein. (341 aa) |
| | LOC101172187 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (267 aa) |
| | LOC101174651 | Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (518 aa) |
| | LOC101161165 | Phosphoethanolamine methyltransferase. (492 aa) |
| | sqle | Squalene epoxidase a. (572 aa) |
| | cyp26b1 | Cytochrome P450 26B1; Belongs to the cytochrome P450 family. (512 aa) |
| | LOC101159946 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa) |
| | kl | Klotho. (975 aa) |
| | LOC101165545 | Elongation of very long chain fatty acids protein. (267 aa) |
| | H2LGI3_ORYLA | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (201 aa) |
| | hsd17b1 | Hydroxysteroid (17-beta) dehydrogenase 1. (291 aa) |
| | hsd11b1l-2 | 11-beta-hydroxysteroid dehydrogenase type 3. (285 aa) |
| | elovl7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (294 aa) |
| | idi1 | Isopentenyl-diphosphate delta isomerase 1. (282 aa) |
| | LOC101162519 | O-acyltransferase. (530 aa) |
| | cyp19b | Aromatase B; Belongs to the cytochrome P450 family. (499 aa) |
| | LOC101156321 | Fatty acid desaturase 2. (445 aa) |
| | LOC101156571 | Fatty acid desaturase 2. (445 aa) |
| | LOC101156814 | Fatty acid desaturase 2. (442 aa) |
| | nsdhl | NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (345 aa) |
| | LOC101157155 | Cytochrome P450, family 21, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (519 aa) |
| | LOC101163495 | Trans-2,3-enoyl-CoA reductase a. (325 aa) |
| | cyp11a | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (517 aa) |
| | LOC101173499 | Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (491 aa) |
| | mvk | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | LOC101165994 | 20beta-hydroxysteroid dehydrogenase type2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | LOC101160349 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (512 aa) |
| | LOC101156734 | Cholesterol 25-hydroxylase like 1, tandem duplicate 2; Belongs to the sterol desaturase family. (283 aa) |
| | msmo1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (291 aa) |
| | LOC101157212 | Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family. (278 aa) |
| | LOC101172512 | Zgc:153372. (362 aa) |
| | ebp | EBP cholestenol delta-isomerase. (259 aa) |
| | r3hdm4 | R3H domain containing 4. (255 aa) |
| | LOC101157291 | Zgc:194242. (196 aa) |
| | 3bhsd | 3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (374 aa) |
| | mvd | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (396 aa) |
| | srebf1 | Sterol regulatory element binding transcription factor 1. (1159 aa) |
| | hacd2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (244 aa) |
| | elovl5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (294 aa) |
| | LOC101175691 | Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (527 aa) |
| | fdps | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (360 aa) |
| | insig1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (279 aa) |
| | cyp11b | Cytochrome P450 11beta; Belongs to the cytochrome P450 family. (541 aa) |
| | LOC101165021 | Uncharacterized protein. (507 aa) |
| | LOC101165274 | Uncharacterized protein. (507 aa) |
| | tm7sf2 | Transmembrane 7 superfamily member 2. (431 aa) |
| | HSD17B7 | Hydroxysteroid 17-beta dehydrogenase 7. (372 aa) |
| | hacd1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (290 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (326 aa) |
| | LOC110013324 | UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (542 aa) |
| | LOC100125518 | UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (540 aa) |
| | LOC101156406 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa) |
| | sigmar1 | Sigma non-opioid intracellular receptor 1. (201 aa) |
| | hacd4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (176 aa) |
| | acot13 | Acyl-CoA thioesterase 13. (142 aa) |
| | NPC1L1 | NPC1 like intracellular cholesterol transporter 1. (1297 aa) |
| | mbtps1 | Membrane-bound transcription factor peptidase, site 1. (1066 aa) |
| | LOC101165182 | Si:ch73-334d15.1; Belongs to the UDP-glycosyltransferase family. (552 aa) |
| | sdr42e1 | Short chain dehydrogenase/reductase family 42E, member 1; Belongs to the 3-beta-HSD family. (384 aa) |
| | LOC101161691 | F-box protein 30b. (747 aa) |
| | srd5a1 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (264 aa) |
| | cyp1a | Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (521 aa) |
| | srebf2 | Sterol regulatory element binding transcription factor 2. (1179 aa) |
| | LOC101156051 | Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (516 aa) |
| | tecr | Trans-2,3-enoyl-CoA reductase b. (308 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (710 aa) |
| | LOC101158433 | Hydroxysteroid (17-beta) dehydrogenase 7. (311 aa) |
| | dhcr7 | 7-dehydrocholesterol reductase. (518 aa) |
| | nus1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (285 aa) |
| | ERG28 | Ergosterol biosynthesis 28 homolog. (143 aa) |
| | soat1 | O-acyltransferase. (558 aa) |
| | IMPG1 | Interphotoreceptor matrix proteoglycan 1. (783 aa) |
| | LOC100125499 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (865 aa) |
| | fdft1 | Farnesyl-diphosphate farnesyltransferase 1. (422 aa) |
| | LOC101157008 | Cytochrome P450, family 8, subfamily B, polypeptide 2; Belongs to the cytochrome P450 family. (511 aa) |
| | hsdl1 | Hydroxysteroid dehydrogenase like 1. (312 aa) |
| | npc1 | Niemann-Pick disease, type C1. (1271 aa) |
| | hao1 | Hydroxyacid oxidase (glycolate oxidase) 1. (426 aa) |
| | cyp17 | Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction; Belongs to the cytochrome P450 family. (595 aa) |
| | pmvk | Phosphomevalonate kinase. (161 aa) |
| | ch25h | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (251 aa) |
| | LOC101173361 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa) |
| | cyp3a | Uncharacterized protein. (500 aa) |
| | H2N0C8_ORYLA | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. (200 aa) |
| | LOC100125517 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa) |
| | dennd6b | DENN/MADD domain containing 6B. (575 aa) |
| | elovl6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (272 aa) |
| | LOC101174401 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa) |
| | LOC101158375 | Glucuronokinase with putative uridyl pyrophosphorylase. (634 aa) |
| | pdss1 | Prenyl (decaprenyl) diphosphate synthase, subunit 1; Belongs to the FPP/GGPP synthase family. (419 aa) |
| | npc2 | Niemann-Pick disease, type C2. (149 aa) |
| | dhcr24 | 24-dehydrocholesterol reductase. (532 aa) |
| | LOC101160151 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (522 aa) |
| | LOC100125532 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (294 aa) |
| | LOC101161285 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (331 aa) |
| | lbr | Lamin B receptor. (597 aa) |
| | dhdds | Alkyl transferase; Belongs to the UPP synthase family. (346 aa) |
| | hmgcs1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (513 aa) |
| | scap | SREBF chaperone. (1355 aa) |
| | pdss2 | Prenyl (decaprenyl) diphosphate synthase, subunit 2; Belongs to the FPP/GGPP synthase family. (384 aa) |
| | LOC101173360 | RUN and SH3 domain containing 2. (1505 aa) |
| | LOC101166505 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | LOC101172816 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase; Belongs to the 3-beta-HSD family. (366 aa) |
| | LOC101168388 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa) |
| | LOC101171706 | Trans-2,3-enoyl-CoA reductase-like 2a. (328 aa) |
| | ENSORLP00000034875 | Uncharacterized protein. (112 aa) |
| | LOC110013325 | L-threonine dehydrogenase 2. (371 aa) |
| | LOC111948904 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa) |
| | hacd3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (369 aa) |
| | FBXO40 | F-box protein 40. (668 aa) |
| | LOC101159204 | Myelin basic protein a. (185 aa) |
| | LOC101157865 | Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family. (277 aa) |
| | ENSORLP00000038567 | RUN domain-containing protein. (116 aa) |
| | LOC110016637 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (287 aa) |
| | LOC101166888 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (853 aa) |
| | sc5d | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa) |
| | hsd17b3 | Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (349 aa) |
| | LOC101160884 | Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa) |
| | LOC101155491 | F-box protein 30a. (720 aa) |
| | rusc1 | Uncharacterized protein. (1876 aa) |
| | ggps1 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (315 aa) |
| | LOC101157810 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (314 aa) |
| | LOC101175390 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (377 aa) |
| | LOC101175367 | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa) |
| | LOC101157258 | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (736 aa) |
| | miox | Myo-inositol oxygenase. (285 aa) |
| | LOC101168572 | Elongation of very long chain fatty acids protein. (269 aa) |
| | LOC101156869 | 3-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (253 aa) |
