12 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101172160	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	LOC101165394	GRB2 related adaptor protein 2a. (283 aa)
	LOC101174825	Fibroblast growth factor receptor substrate 3. (608 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (449 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (582 aa)
	grb2	Growth factor receptor-bound protein 2b. (218 aa)
	erbb4	Receptor protein-tyrosine kinase. (1375 aa)
	sos1	Son of sevenless homolog 1 (Drosophila). (1297 aa)
	SHC4	SHC adaptor protein 4. (534 aa)
	LOC101165379	Receptor protein-tyrosine kinase. (1494 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	LOC101157091	PH domain-containing protein. (761 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101157091	LOC101165379	ENSORLP00000040455	ENSORLP00000031995	PH domain-containing protein.	Receptor protein-tyrosine kinase.	0.609
LOC101157091	LOC101165394	ENSORLP00000040455	ENSORLP00000001729	PH domain-containing protein.	GRB2 related adaptor protein 2a.	0.894
LOC101157091	LOC101172160	ENSORLP00000040455	ENSORLP00000000761	PH domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.863
LOC101157091	LOC101174825	ENSORLP00000040455	ENSORLP00000002237	PH domain-containing protein.	Fibroblast growth factor receptor substrate 3.	0.599
LOC101157091	SHC4	ENSORLP00000040455	ENSORLP00000027207	PH domain-containing protein.	SHC adaptor protein 4.	0.665
LOC101157091	erbb4	ENSORLP00000040455	ENSORLP00000020056	PH domain-containing protein.	Receptor protein-tyrosine kinase.	0.609
LOC101157091	grb2	ENSORLP00000040455	ENSORLP00000019097	PH domain-containing protein.	Growth factor receptor-bound protein 2b.	0.997
LOC101157091	ptpn11	ENSORLP00000040455	ENSORLP00000039210	PH domain-containing protein.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.863
LOC101157091	ptpn6	ENSORLP00000040455	ENSORLP00000015555	PH domain-containing protein.	Protein tyrosine phosphatase non-receptor type 6.	0.863
LOC101157091	shc1	ENSORLP00000040455	ENSORLP00000012223	PH domain-containing protein.	SHC (Src homology 2 domain containing) transforming protein 1.	0.665
LOC101157091	sos1	ENSORLP00000040455	ENSORLP00000026907	PH domain-containing protein.	Son of sevenless homolog 1 (Drosophila).	0.516
LOC101165379	LOC101157091	ENSORLP00000031995	ENSORLP00000040455	Receptor protein-tyrosine kinase.	PH domain-containing protein.	0.609
LOC101165379	LOC101165394	ENSORLP00000031995	ENSORLP00000001729	Receptor protein-tyrosine kinase.	GRB2 related adaptor protein 2a.	0.671
LOC101165379	LOC101172160	ENSORLP00000031995	ENSORLP00000000761	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.596
LOC101165379	SHC4	ENSORLP00000031995	ENSORLP00000027207	Receptor protein-tyrosine kinase.	SHC adaptor protein 4.	0.968
LOC101165379	erbb4	ENSORLP00000031995	ENSORLP00000020056	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.901
LOC101165379	grb2	ENSORLP00000031995	ENSORLP00000019097	Receptor protein-tyrosine kinase.	Growth factor receptor-bound protein 2b.	0.983
LOC101165379	ptpn11	ENSORLP00000031995	ENSORLP00000039210	Receptor protein-tyrosine kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.596
LOC101165379	ptpn6	ENSORLP00000031995	ENSORLP00000015555	Receptor protein-tyrosine kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.596
LOC101165379	shc1	ENSORLP00000031995	ENSORLP00000012223	Receptor protein-tyrosine kinase.	SHC (Src homology 2 domain containing) transforming protein 1.	0.968