(23 nodes) Mixed, incl. Caveolin, and Flotillin network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	LOC101164911	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (428 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	LOC101155616	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (424 aa)
	flot2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (432 aa)
	LOC101157726	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (465 aa)
	LOC101156206	Caveolae associated protein 1b. (469 aa)
	ttf1	Si:ch73-376l24.4. (610 aa)
	lrrc10	Leucine rich repeat containing 10. (275 aa)
	ocln	Occludin b. (477 aa)
	LOC101162818	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (181 aa)
	pdgfra	Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1460 aa)
	LOC101160233	Tight junction protein 1b; Belongs to the MAGUK family. (1856 aa)
	LOC101163521	Zgc:154006. (518 aa)
	cavin2-2	Caveolae associated protein 2a. (591 aa)
	LOC101156574	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (189 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	LOC110014685	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (219 aa)
	LOC101169436	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (545 aa)
	LOC101164882	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (237 aa)
	LOC101163673	Occludin a. (497 aa)
	cavin1	Caveolae associated protein 1a. (420 aa)
	ENSORLP00000045591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (130 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000045591	LOC101155616	ENSORLP00000045591	ENSORLP00000008720	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.738
ENSORLP00000045591	LOC101156206	ENSORLP00000045591	ENSORLP00000017990	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1b.	0.722
ENSORLP00000045591	LOC101157726	ENSORLP00000045591	ENSORLP00000016266	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.730
ENSORLP00000045591	LOC101162818	ENSORLP00000045591	ENSORLP00000024539	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.555
ENSORLP00000045591	LOC101164911	ENSORLP00000045591	ENSORLP00000002427	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.491
ENSORLP00000045591	LOC110014685	ENSORLP00000045591	ENSORLP00000040165	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.973
ENSORLP00000045591	cav3	ENSORLP00000045591	ENSORLP00000000896	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.555
ENSORLP00000045591	cavin1	ENSORLP00000045591	ENSORLP00000042915	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1a.	0.722
ENSORLP00000045591	flot2	ENSORLP00000045591	ENSORLP00000014302	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.491
ENSORLP00000045591	lrrc10	ENSORLP00000045591	ENSORLP00000020607	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Leucine rich repeat containing 10.	0.599
LOC101155616	ENSORLP00000045591	ENSORLP00000008720	ENSORLP00000045591	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.738
LOC101155616	LOC101156206	ENSORLP00000008720	ENSORLP00000017990	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolae associated protein 1b.	0.403
LOC101155616	LOC101156574	ENSORLP00000008720	ENSORLP00000033020	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.678
LOC101155616	LOC101157726	ENSORLP00000008720	ENSORLP00000016266	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.544
LOC101155616	LOC101162818	ENSORLP00000008720	ENSORLP00000024539	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.653
LOC101155616	LOC101164480	ENSORLP00000008720	ENSORLP00000036233	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Tyrosine-protein kinase.	0.485
LOC101155616	LOC101164882	ENSORLP00000008720	ENSORLP00000042117	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.678
LOC101155616	LOC101164911	ENSORLP00000008720	ENSORLP00000002427	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.590
LOC101155616	LOC110014685	ENSORLP00000008720	ENSORLP00000040165	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.689
LOC101155616	SRC	ENSORLP00000008720	ENSORLP00000008431	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	Tyrosine-protein kinase.	0.486