22 items (Oryzias latipes) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	fgf19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
	Fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	klb	Klotho beta. (1045 aa)
	LOC101161650	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
	sos2	Son of sevenless homolog 2 (Drosophila). (1323 aa)
	fgfr2	Fibroblast growth factor receptor. (832 aa)
	LOC100049521	Fibroblast growth factor receptor 4. (1075 aa)
	fgfr1	Fibroblast growth factor receptor. (833 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (263 aa)
	fgfr3	Fibroblast growth factor receptor. (820 aa)
	LOC101165069	Fibroblast growth factor receptor like 1a. (494 aa)
	LOC101162992	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
	ENSORLP00000032568	Fibroblast growth factor binding protein 1b. (196 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	fgf18	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	fgf10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	fgf20a	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
	LOC101155126	Fibroblast growth factor receptor. (740 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000032568	Fgf1	ENSORLP00000032568	ENSORLP00000001852	Fibroblast growth factor binding protein 1b.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.750
ENSORLP00000032568	LOC101161650	ENSORLP00000032568	ENSORLP00000007561	Fibroblast growth factor binding protein 1b.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.750
ENSORLP00000032568	LOC101162992	ENSORLP00000032568	ENSORLP00000030909	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.603
ENSORLP00000032568	fgf10	ENSORLP00000032568	ENSORLP00000040733	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.603
ENSORLP00000032568	fgf18	ENSORLP00000032568	ENSORLP00000038417	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.637
ENSORLP00000032568	fgf20a	ENSORLP00000032568	ENSORLP00000042676	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.515
ENSORLP00000032568	fgf3	ENSORLP00000032568	ENSORLP00000000370	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.757
ENSORLP00000032568	fgf4	ENSORLP00000032568	ENSORLP00000000362	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.637
ENSORLP00000032568	fgf5	ENSORLP00000032568	ENSORLP00000038193	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.637
ENSORLP00000032568	fgf7	ENSORLP00000032568	ENSORLP00000002929	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.819
ENSORLP00000032568	fgf8	ENSORLP00000032568	ENSORLP00000042553	Fibroblast growth factor binding protein 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.636
Fgf1	ENSORLP00000032568	ENSORLP00000001852	ENSORLP00000032568	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor binding protein 1b.	0.750
Fgf1	LOC100049521	ENSORLP00000001852	ENSORLP00000017514	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor receptor 4.	0.958
Fgf1	LOC101155126	ENSORLP00000001852	ENSORLP00000045140	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor receptor.	0.911
Fgf1	LOC101162992	ENSORLP00000001852	ENSORLP00000030909	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.481
Fgf1	LOC101165069	ENSORLP00000001852	ENSORLP00000030183	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor receptor like 1a.	0.640
Fgf1	fgf10	ENSORLP00000001852	ENSORLP00000040733	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.483
Fgf1	fgf18	ENSORLP00000001852	ENSORLP00000038417	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.595
Fgf1	fgf19	ENSORLP00000001852	ENSORLP00000000352	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.584
Fgf1	fgf23	ENSORLP00000001852	ENSORLP00000019815	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.575