(16 nodes) Regulation by c-FLIP, and Amyloid fibril formation network (Oryzias latipes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101168078	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (481 aa)
	LOC100125536	Uncharacterized protein; Belongs to the peptidase C14A family. (389 aa)
	casp8	Uncharacterized protein; Belongs to the peptidase C14A family. (481 aa)
	tnfsf10	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (281 aa)
	LOC101172365	TNF superfamily member 10; Belongs to the tumor necrosis factor family. (280 aa)
	cflar	FLICE-like inhibitory protein; Belongs to the peptidase C14A family. (460 aa)
	LOC101160750	Protein kinase domain-containing protein. (460 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (675 aa)
	LOC101168038	Protein kinase domain-containing protein. (509 aa)
	LOC101168285	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (415 aa)
	LOC101172833	Tumor necrosis factor receptor superfamily, member a. (447 aa)
	fas	Uncharacterized protein. (310 aa)
	LOC101159737	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (269 aa)
	tradd	Tnfrsf1a-associated via death domain. (321 aa)
	fadd	Uncharacterized protein. (192 aa)
	LOC101173230	Uncharacterized protein. (340 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100125536	LOC101159737	ENSORLP00000013993	ENSORLP00000040434	Uncharacterized protein; Belongs to the peptidase C14A family.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.872
LOC100125536	LOC101160750	ENSORLP00000013993	ENSORLP00000026094	Uncharacterized protein; Belongs to the peptidase C14A family.	Protein kinase domain-containing protein.	0.546
LOC100125536	LOC101168038	ENSORLP00000013993	ENSORLP00000029474	Uncharacterized protein; Belongs to the peptidase C14A family.	Protein kinase domain-containing protein.	0.983
LOC100125536	LOC101168078	ENSORLP00000013993	ENSORLP00000011349	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	0.985
LOC100125536	LOC101168285	ENSORLP00000013993	ENSORLP00000029843	Uncharacterized protein; Belongs to the peptidase C14A family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.983
LOC100125536	LOC101172833	ENSORLP00000013993	ENSORLP00000032250	Uncharacterized protein; Belongs to the peptidase C14A family.	Tumor necrosis factor receptor superfamily, member a.	0.869
LOC100125536	LOC101173230	ENSORLP00000013993	ENSORLP00000045623	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.622
LOC100125536	casp8	ENSORLP00000013993	ENSORLP00000014046	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.905
LOC100125536	cflar	ENSORLP00000013993	ENSORLP00000020363	Uncharacterized protein; Belongs to the peptidase C14A family.	FLICE-like inhibitory protein; Belongs to the peptidase C14A family.	0.994
LOC100125536	fadd	ENSORLP00000013993	ENSORLP00000043356	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.996
LOC100125536	fas	ENSORLP00000013993	ENSORLP00000038826	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.932
LOC100125536	ripk1	ENSORLP00000013993	ENSORLP00000026458	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.996
LOC100125536	tnfsf10	ENSORLP00000013993	ENSORLP00000014844	Uncharacterized protein; Belongs to the peptidase C14A family.	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.	0.837
LOC100125536	tradd	ENSORLP00000013993	ENSORLP00000040480	Uncharacterized protein; Belongs to the peptidase C14A family.	Tnfrsf1a-associated via death domain.	0.988
LOC101159737	LOC100125536	ENSORLP00000040434	ENSORLP00000013993	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.872
LOC101159737	LOC101168038	ENSORLP00000040434	ENSORLP00000029474	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein.	0.424
LOC101159737	LOC101168078	ENSORLP00000040434	ENSORLP00000011349	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily.	0.424
LOC101159737	LOC101168285	ENSORLP00000040434	ENSORLP00000029843	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.424
LOC101159737	LOC101172833	ENSORLP00000040434	ENSORLP00000032250	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Tumor necrosis factor receptor superfamily, member a.	0.876
LOC101159737	LOC101173230	ENSORLP00000040434	ENSORLP00000045623	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.653