(49 nodes) Mixed, incl. Dopamine Neurotransmitter Release Cycle, and RIMS-binding protein 1/2/3 network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101172259	Zgc:113149. (422 aa)
	H2L8K4_ORYLA	Regulating synaptic membrane exocytosis 1a. (870 aa)
	slc18a2	Solute carrier family 18 member 2. (480 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1283 aa)
	H2LBE3_ORYLA	C2 domain-containing protein. (313 aa)
	LOC101174001	Uncharacterized protein. (253 aa)
	LOC101158236	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (579 aa)
	LOC105355399	Si:ch211-105f12.2. (221 aa)
	rab3c	RAB3C, member RAS oncogene family. (226 aa)
	LOC101172563	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (935 aa)
	LOC101174515	Regulating synaptic membrane exocytosis 3. (323 aa)
	LOC101164677	Uncharacterized protein. (218 aa)
	LOC101168608	Lin-7 homolog C (C. elegans); Belongs to the eukaryotic ribosomal protein P1/P2 family. (287 aa)
	LOC101164402	Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family. (615 aa)
	LOC101160191	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (552 aa)
	LOC101162033	Amyloid beta precursor protein binding family A member 3. (704 aa)
	rab3a	RAB3A, member RAS oncogene family, b. (219 aa)
	LOC101162836	Synaptotagmin Ib. (407 aa)
	dlg5	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1967 aa)
	mpp1	Membrane protein, palmitoylated 1; Belongs to the MAGUK family. (467 aa)
	tspoap1	Uncharacterized protein. (2306 aa)
	UNC13C	Unc-13 homolog C. (1122 aa)
	LOC101163826	Synapsin I. (631 aa)
	LOC101166648	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (1077 aa)
	LOC101168719	Uncharacterized protein. (185 aa)
	LOC101175058	Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (553 aa)
	LOC101159330	Unc-13 homolog Ba (C. elegans). (1200 aa)
	LOC101157206	Uncharacterized protein. (430 aa)
	ENSORLP00000026521	Uncharacterized protein. (877 aa)
	ENSORLP00000028044	PDZ domain-containing protein. (436 aa)
	syt1	Synaptotagmin Ia. (536 aa)
	lin7b	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (220 aa)
	cask	Uncharacterized protein; Belongs to the MAGUK family. (954 aa)
	ENSORLP00000031636	C2 domain-containing protein. (317 aa)
	lin7a	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (217 aa)
	ENSORLP00000034554	C2 domain-containing protein. (288 aa)
	apba2	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (919 aa)
	ENSORLP00000035540	Uncharacterized protein. (212 aa)
	stxbp3	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (598 aa)
	SLC18A1	Solute carrier family 18 member A1. (541 aa)
	KAZN	Kazrin, periplakin interacting protein a. (937 aa)
	LOC101161806	Synaptotagmin IIa. (432 aa)
	UNC13B	Unc-13 homolog B. (1474 aa)
	LOC101159330-2	Uncharacterized protein. (293 aa)
	UNC13C-2	Uncharacterized protein. (1427 aa)
	LOC101160976	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (820 aa)
	LOC101174933	Uncharacterized protein. (1339 aa)
	LOC111947167	C2 domain-containing protein. (257 aa)
	LOC101155860	Uncharacterized protein; Belongs to the MAGUK family. (576 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000026521	ENSORLP00000031636	ENSORLP00000026521	ENSORLP00000031636	Uncharacterized protein.	C2 domain-containing protein.	0.909
ENSORLP00000026521	ENSORLP00000034554	ENSORLP00000026521	ENSORLP00000034554	Uncharacterized protein.	C2 domain-containing protein.	0.914
ENSORLP00000026521	ENSORLP00000035540	ENSORLP00000026521	ENSORLP00000035540	Uncharacterized protein.	Uncharacterized protein.	0.988
ENSORLP00000026521	H2LBE3_ORYLA	ENSORLP00000026521	ENSORLP00000003215	Uncharacterized protein.	C2 domain-containing protein.	0.909
ENSORLP00000026521	KAZN	ENSORLP00000026521	ENSORLP00000040329	Uncharacterized protein.	Kazrin, periplakin interacting protein a.	0.800
ENSORLP00000026521	LOC101155860	ENSORLP00000026521	ENSORLP00000045689	Uncharacterized protein.	Uncharacterized protein; Belongs to the MAGUK family.	0.502
ENSORLP00000026521	LOC101157206	ENSORLP00000026521	ENSORLP00000026249	Uncharacterized protein.	Uncharacterized protein.	0.494
ENSORLP00000026521	LOC101158236	ENSORLP00000026521	ENSORLP00000005421	Uncharacterized protein.	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.	0.502
ENSORLP00000026521	LOC101159330	ENSORLP00000026521	ENSORLP00000024596	Uncharacterized protein.	Unc-13 homolog Ba (C. elegans).	0.992
ENSORLP00000026521	LOC101159330-2	ENSORLP00000026521	ENSORLP00000041319	Uncharacterized protein.	Uncharacterized protein.	0.992
ENSORLP00000026521	LOC101160191	ENSORLP00000026521	ENSORLP00000009875	Uncharacterized protein.	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family.	0.502
ENSORLP00000026521	LOC101160976	ENSORLP00000026521	ENSORLP00000043066	Uncharacterized protein.	Amyloid beta (A4) precursor protein-binding, family A, member 2a.	0.658
ENSORLP00000026521	LOC101161806	ENSORLP00000026521	ENSORLP00000041194	Uncharacterized protein.	Synaptotagmin IIa.	0.494
ENSORLP00000026521	LOC101162033	ENSORLP00000026521	ENSORLP00000010005	Uncharacterized protein.	Amyloid beta precursor protein binding family A member 3.	0.658
ENSORLP00000026521	LOC101162836	ENSORLP00000026521	ENSORLP00000011014	Uncharacterized protein.	Synaptotagmin Ib.	0.494
ENSORLP00000026521	LOC101163826	ENSORLP00000026521	ENSORLP00000016523	Uncharacterized protein.	Synapsin I.	0.746
ENSORLP00000026521	LOC101164402	ENSORLP00000026521	ENSORLP00000008116	Uncharacterized protein.	Syntaxin binding protein 2; Belongs to the STXBP/unc-18/SEC1 family.	0.968
ENSORLP00000026521	LOC101164677	ENSORLP00000026521	ENSORLP00000006885	Uncharacterized protein.	Uncharacterized protein.	0.842
ENSORLP00000026521	LOC101166648	ENSORLP00000026521	ENSORLP00000016914	Uncharacterized protein.	Amyloid beta (A4) precursor protein-binding, family A, member 1b.	0.658
ENSORLP00000026521	LOC101168608	ENSORLP00000026521	ENSORLP00000007427	Uncharacterized protein.	Lin-7 homolog C (C. elegans); Belongs to the eukaryotic ribosomal protein P1/P2 family.	0.517