(12 nodes) Beta-catenin destruction complex, and Dishevelled family network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101171502	Uncharacterized protein. (768 aa)
	axin1	Axin 1. (854 aa)
	LOC101159441	Axin 2 (conductin, axil). (841 aa)
	H2M0Q7_ORYLA	APC membrane recruitment protein 1. (960 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2227 aa)
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate a. (216 aa)
	csnk1a1	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily. (353 aa)
	dvl2	Dishevelled segment polarity protein 2. (770 aa)
	apc	APC regulator of WNT signaling pathway. (2204 aa)
	AXIN2	Axin 2. (791 aa)
	LOC101155494	Uncharacterized protein. (883 aa)
	dvl1	Dishevelled segment polarity protein 1a. (728 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	H2M0Q7_ORYLA	ENSORLP00000035131	ENSORLP00000011983	Axin 2.	APC membrane recruitment protein 1.	0.785
AXIN2	LOC101155494	ENSORLP00000035131	ENSORLP00000038069	Axin 2.	Uncharacterized protein.	0.668
AXIN2	LOC101159441	ENSORLP00000035131	ENSORLP00000011155	Axin 2.	Axin 2 (conductin, axil).	0.552
AXIN2	LOC101171502	ENSORLP00000035131	ENSORLP00000004535	Axin 2.	Uncharacterized protein.	0.978
AXIN2	apc	ENSORLP00000035131	ENSORLP00000027563	Axin 2.	APC regulator of WNT signaling pathway.	0.981
AXIN2	apc2	ENSORLP00000035131	ENSORLP00000016561	Axin 2.	APC regulator of WNT signaling pathway 2.	0.915
AXIN2	axin1	ENSORLP00000035131	ENSORLP00000006039	Axin 2.	Axin 1.	0.667
AXIN2	csnk1a1	ENSORLP00000035131	ENSORLP00000025560	Axin 2.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.983
AXIN2	dvl1	ENSORLP00000035131	ENSORLP00000042468	Axin 2.	Dishevelled segment polarity protein 1a.	0.975
AXIN2	dvl2	ENSORLP00000035131	ENSORLP00000026771	Axin 2.	Dishevelled segment polarity protein 2.	0.975
AXIN2	gsk3b	ENSORLP00000035131	ENSORLP00000022469	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate a.	0.926
H2M0Q7_ORYLA	AXIN2	ENSORLP00000011983	ENSORLP00000035131	APC membrane recruitment protein 1.	Axin 2.	0.785
H2M0Q7_ORYLA	LOC101155494	ENSORLP00000011983	ENSORLP00000038069	APC membrane recruitment protein 1.	Uncharacterized protein.	0.833
H2M0Q7_ORYLA	LOC101159441	ENSORLP00000011983	ENSORLP00000011155	APC membrane recruitment protein 1.	Axin 2 (conductin, axil).	0.785
H2M0Q7_ORYLA	LOC101171502	ENSORLP00000011983	ENSORLP00000004535	APC membrane recruitment protein 1.	Uncharacterized protein.	0.790
H2M0Q7_ORYLA	apc	ENSORLP00000011983	ENSORLP00000027563	APC membrane recruitment protein 1.	APC regulator of WNT signaling pathway.	0.906
H2M0Q7_ORYLA	apc2	ENSORLP00000011983	ENSORLP00000016561	APC membrane recruitment protein 1.	APC regulator of WNT signaling pathway 2.	0.906
H2M0Q7_ORYLA	axin1	ENSORLP00000011983	ENSORLP00000006039	APC membrane recruitment protein 1.	Axin 1.	0.833
H2M0Q7_ORYLA	csnk1a1	ENSORLP00000011983	ENSORLP00000025560	APC membrane recruitment protein 1.	Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.	0.768
H2M0Q7_ORYLA	dvl1	ENSORLP00000011983	ENSORLP00000042468	APC membrane recruitment protein 1.	Dishevelled segment polarity protein 1a.	0.429