STRINGSTRING
LOC101168560 LOC101168560 H2L587_ORYLA H2L587_ORYLA LOC101157631 LOC101157631 INHBB INHBB fst fst inha inha LOC101169523 LOC101169523 LOC101170165 LOC101170165 LOC101155037 LOC101155037 zfyve9 zfyve9 LOC101161926 LOC101161926 LOC101171238 LOC101171238 bambi bambi SMAD4 SMAD4 INHBC INHBC LOC101162532 LOC101162532 smad3 smad3 smad6 smad6 smad1 smad1 ACVR1B ACVR1B LOC100144359 LOC100144359 nodal nodal LOC101155815 LOC101155815 gdf3 gdf3 smad2 smad2 tfdp1 tfdp1 LOC101160323 LOC101160323 LOC101159109 LOC101159109 fmod fmod e2f4 e2f4 lefty1 lefty1 LOC101173779 LOC101173779 tgfb3 tgfb3 acvr1 acvr1 rbl1 rbl1 LOC101171650 LOC101171650 smad9 smad9 mstn mstn LOC101173916 LOC101173916 LOC101160003 LOC101160003 ACVR1C ACVR1C LOC101170230 LOC101170230 ski ski Zfyve9 Zfyve9 SMURF2 SMURF2 skil skil LOC101174785 LOC101174785 TGFBR2 TGFBR2 ENSORLP00000042887 ENSORLP00000042887 smad7 smad7 LOC101163504 LOC101163504 ENSORLP00000045700 ENSORLP00000045700
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC101168560Uncharacterized protein. (1850 aa)
H2L587_ORYLADUF3480 domain-containing protein. (297 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
INHBBInhibin subunit beta B. (386 aa)
fstFollistatin a. (321 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (352 aa)
LOC101169523Mothers against decapentaplegic homolog. (425 aa)
LOC101170165Mothers against decapentaplegic homolog. (499 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1096 aa)
LOC101161926Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
LOC101171238V-ski avian sarcoma viral oncogene homolog b. (685 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (257 aa)
SMAD4Mothers against decapentaplegic homolog. (510 aa)
INHBCInhibin beta B chain-like protein. (379 aa)
LOC101162532Southpaw. (413 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
smad6Mothers against decapentaplegic homolog. (488 aa)
smad1Mothers against decapentaplegic homolog. (471 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (456 aa)
LOC100144359TGF_BETA_2 domain-containing protein. (398 aa)
nodalNodal-related 2. (381 aa)
LOC101155815Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
gdf3Growth differentiation factor 3. (376 aa)
smad2Mothers against decapentaplegic homolog. (473 aa)
tfdp1Transcription factor. (413 aa)
LOC101160323E3 ubiquitin-protein ligase. (770 aa)
LOC101159109Mothers against decapentaplegic homolog. (467 aa)
fmodFibromodulin a. (347 aa)
e2f4E2F transcription factor 4. (390 aa)
lefty1Left-right determination factor. (358 aa)
LOC101173779Zinc finger, FYVE domain containing 9b. (660 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (681 aa)
rbl1Retinoblastoma-like 1 (p107). (1112 aa)
LOC101171650Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
smad9Mothers against decapentaplegic homolog. (467 aa)
mstnTGF_BETA_2 domain-containing protein. (424 aa)
LOC101173916Mothers against decapentaplegic homolog. (538 aa)
LOC101160003Mothers against decapentaplegic homolog. (464 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (444 aa)
LOC101170230Inhibin subunit beta Aa. (457 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (739 aa)
Zfyve9SARA domain-containing protein. (101 aa)
SMURF2E3 ubiquitin-protein ligase. (795 aa)
skilSKI-like proto-oncogene a. (746 aa)
LOC101174785TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (587 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (540 aa)
ENSORLP00000042887FYVE domain-containing protein. (78 aa)
smad7Mothers against decapentaplegic homolog. (375 aa)
LOC101163504Mothers against decapentaplegic homolog. (528 aa)
ENSORLP00000045700TGF_BETA_2 domain-containing protein. (131 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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