(65 nodes) Mixed, incl. Deactivation of the beta-catenin transactivating complex, and POU domain network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	znf143	Zinc finger protein 143b. (625 aa)
	sox6a	HMG box domain-containing protein. (814 aa)
	sox2	SOX3 protein. (300 aa)
	LOC101173418	Si:dkey-7e14.3. (246 aa)
	ovca2	OVCA2 serine hydrolase domain containing. (223 aa)
	prxl2c	Peroxiredoxin like 2C. (248 aa)
	six2	SIX homeobox 2a. (290 aa)
	H2LJV9_ORYLA	Transcription factor SOX. (310 aa)
	amh	Anti-muellerian hormone. (496 aa)
	H2LK11_ORYLA	BTB domain-containing protein. (257 aa)
	LOC101162366	Zgc:194189. (263 aa)
	klf4	Kruppel-like factor 4. (425 aa)
	sox6b	SRY-box containing gene 6b. (804 aa)
	H2LRZ8_ORYLA	POU domain protein. (155 aa)
	hoxc11	Homeobox C11a. (314 aa)
	sox9	HMG box domain-containing protein. (476 aa)
	LOC101175353	SIX homeobox 7. (259 aa)
	sox8	SRY-box containing gene 8. (465 aa)
	gnrh-r3	Gonadotropin-releasing hormone receptor 3. (394 aa)
	bmp15	Bone morphogenetic protein 15. (444 aa)
	misrii	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (495 aa)
	Fezf2	FEZ family zinc finger 2. (402 aa)
	foxd3	Forkhead box D3. (398 aa)
	LOC100049520	POU domain protein. (469 aa)
	Kctd12	Potassium channel tetramerisation domain containing 12.1. (294 aa)
	Sox2	SRY-box transcription factor 2. (243 aa)
	dax1	NR LBD domain-containing protein. (287 aa)
	sox13	SRY-box transcription factor 13. (588 aa)
	sox1	HMG box domain-containing protein. (322 aa)
	wt1	Uncharacterized protein. (435 aa)
	LOC101174234	POU domain protein. (344 aa)
	pou2f1	POU domain protein. (715 aa)
	LOC101161934	F-box domain-containing protein. (400 aa)
	pou2f3	POU domain protein. (395 aa)
	sox11	Transcription factor SOX. (359 aa)
	figla	BHLH domain-containing protein. (200 aa)
	sall4	Spalt-like transcription factor 4. (1059 aa)
	snai2	Snail family zinc finger 2. (260 aa)
	sox21	SRY-box containing gene 21. (244 aa)
	foxl2	Forkhead box L2. (306 aa)
	dmy	Doublesex- and mab-3-related transcription factor 1; Transcription factor that acts both as a transcription. (283 aa)
	sox7	Uncharacterized protein. (407 aa)
	pax3	Paired box 3b. (496 aa)
	LOC111949309	HMG box domain-containing protein. (338 aa)
	bsx	Brain-specific homeobox. (230 aa)
	ENSORLP00000029293	Uncharacterized protein. (130 aa)
	nanog	Homeobox domain-containing protein. (420 aa)
	pou2af1	Uncharacterized protein. (296 aa)
	LOC110017107	SRY-box transcription factor 19b. (302 aa)
	sox5	HMG box domain-containing protein. (880 aa)
	sox10	SRY-box containing gene 10b. (484 aa)
	LOC110013551	Transcription factor SOX. (360 aa)
	sall3	Spalt-like transcription factor 3a. (1334 aa)
	lmo7	LIM domain 7a. (1357 aa)
	LOC111949029	HMG box domain-containing protein. (224 aa)
	nr5a2	Uncharacterized protein. (520 aa)
	gsdf	Gonadal soma derived factor. (216 aa)
	LOC111947099	POU domain protein. (345 aa)
	LOC101166143	Growth differentiation factor 9. (435 aa)
	LOC101162433	POU domain protein. (436 aa)
	igf2bp2	Insulin-like growth factor 2 mRNA binding protein 2a. (611 aa)
	LOC101162736	Sox10a. (498 aa)
	LOC100049282	Retinoic acid receptor, alpha a. (455 aa)
	pou2f2	POU domain protein. (739 aa)
	LOC101172063	LIM domain 7b. (1344 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000029293	LOC100049520	ENSORLP00000029293	ENSORLP00000013122	Uncharacterized protein.	POU domain protein.	0.657
ENSORLP00000029293	bsx	ENSORLP00000029293	ENSORLP00000028800	Uncharacterized protein.	Brain-specific homeobox.	0.437
ENSORLP00000029293	nanog	ENSORLP00000029293	ENSORLP00000030179	Uncharacterized protein.	Homeobox domain-containing protein.	0.616
Fezf2	prxl2c	ENSORLP00000012733	ENSORLP00000004932	FEZ family zinc finger 2.	Peroxiredoxin like 2C.	0.561
Fezf2	sox5	ENSORLP00000012733	ENSORLP00000034239	FEZ family zinc finger 2.	HMG box domain-containing protein.	0.612
Fezf2	sox7	ENSORLP00000012733	ENSORLP00000026708	FEZ family zinc finger 2.	Uncharacterized protein.	0.574
H2LJV9_ORYLA	LOC100049520	ENSORLP00000006304	ENSORLP00000013122	Transcription factor SOX.	POU domain protein.	0.529
H2LJV9_ORYLA	sox6a	ENSORLP00000006304	ENSORLP00000001551	Transcription factor SOX.	HMG box domain-containing protein.	0.441
H2LJV9_ORYLA	sox6b	ENSORLP00000006304	ENSORLP00000008419	Transcription factor SOX.	SRY-box containing gene 6b.	0.441
H2LK11_ORYLA	LOC101175353	ENSORLP00000006360	ENSORLP00000010004	BTB domain-containing protein.	SIX homeobox 7.	0.676
H2LK11_ORYLA	foxd3	ENSORLP00000006360	ENSORLP00000012977	BTB domain-containing protein.	Forkhead box D3.	0.596
H2LK11_ORYLA	sox1	ENSORLP00000006360	ENSORLP00000015156	BTB domain-containing protein.	HMG box domain-containing protein.	0.642
H2LRZ8_ORYLA	pou2af1	ENSORLP00000008856	ENSORLP00000030341	POU domain protein.	Uncharacterized protein.	0.631
H2LRZ8_ORYLA	znf143	ENSORLP00000008856	ENSORLP00000001395	POU domain protein.	Zinc finger protein 143b.	0.563
Kctd12	LOC101175353	ENSORLP00000014227	ENSORLP00000010004	Potassium channel tetramerisation domain containing 12.1.	SIX homeobox 7.	0.676
Kctd12	foxd3	ENSORLP00000014227	ENSORLP00000012977	Potassium channel tetramerisation domain containing 12.1.	Forkhead box D3.	0.596
Kctd12	sox1	ENSORLP00000014227	ENSORLP00000015156	Potassium channel tetramerisation domain containing 12.1.	HMG box domain-containing protein.	0.641
LOC100049282	hoxc11	ENSORLP00000045378	ENSORLP00000009920	Retinoic acid receptor, alpha a.	Homeobox C11a.	0.681
LOC100049520	ENSORLP00000029293	ENSORLP00000013122	ENSORLP00000029293	POU domain protein.	Uncharacterized protein.	0.657
LOC100049520	H2LJV9_ORYLA	ENSORLP00000013122	ENSORLP00000006304	POU domain protein.	Transcription factor SOX.	0.529