(11 nodes) Mixed, incl. Nuclear estrogen receptor activity, and Somatic sex determination network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rnf14	RBR-type E3 ubiquitin transferase. (479 aa)
	ar-alpha	Uncharacterized protein. (687 aa)
	LOC100049233	Androgen receptor beta subtype. (744 aa)
	NCOA3	Nuclear receptor coactivator. (1496 aa)
	esr2	Uncharacterized protein. (574 aa)
	esr2-2	Uncharacterized protein. (541 aa)
	foxa1	Fork-head domain-containing protein. (407 aa)
	LOC101168870	E1A binding protein p300 b. (2760 aa)
	sp1	Sp1 transcription factor. (467 aa)
	pgr	Uncharacterized protein. (667 aa)
	esr1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (634 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100049233	LOC101168870	ENSORLP00000011941	ENSORLP00000032567	Androgen receptor beta subtype.	E1A binding protein p300 b.	0.640
LOC100049233	NCOA3	ENSORLP00000011941	ENSORLP00000015195	Androgen receptor beta subtype.	Nuclear receptor coactivator.	0.730
LOC100049233	ar-alpha	ENSORLP00000011941	ENSORLP00000010323	Androgen receptor beta subtype.	Uncharacterized protein.	0.908
LOC100049233	esr1	ENSORLP00000011941	ENSORLP00000042539	Androgen receptor beta subtype.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.647
LOC100049233	foxa1	ENSORLP00000011941	ENSORLP00000024270	Androgen receptor beta subtype.	Fork-head domain-containing protein.	0.504
LOC100049233	pgr	ENSORLP00000011941	ENSORLP00000034899	Androgen receptor beta subtype.	Uncharacterized protein.	0.615
LOC100049233	rnf14	ENSORLP00000011941	ENSORLP00000001809	Androgen receptor beta subtype.	RBR-type E3 ubiquitin transferase.	0.703
LOC100049233	sp1	ENSORLP00000011941	ENSORLP00000034132	Androgen receptor beta subtype.	Sp1 transcription factor.	0.490
LOC101168870	LOC100049233	ENSORLP00000032567	ENSORLP00000011941	E1A binding protein p300 b.	Androgen receptor beta subtype.	0.640
LOC101168870	NCOA3	ENSORLP00000032567	ENSORLP00000015195	E1A binding protein p300 b.	Nuclear receptor coactivator.	0.667
LOC101168870	ar-alpha	ENSORLP00000032567	ENSORLP00000010323	E1A binding protein p300 b.	Uncharacterized protein.	0.640
LOC101168870	esr1	ENSORLP00000032567	ENSORLP00000042539	E1A binding protein p300 b.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.768
LOC101168870	esr2	ENSORLP00000032567	ENSORLP00000022181	E1A binding protein p300 b.	Uncharacterized protein.	0.768
LOC101168870	esr2-2	ENSORLP00000032567	ENSORLP00000022556	E1A binding protein p300 b.	Uncharacterized protein.	0.768
LOC101168870	foxa1	ENSORLP00000032567	ENSORLP00000024270	E1A binding protein p300 b.	Fork-head domain-containing protein.	0.560
LOC101168870	pgr	ENSORLP00000032567	ENSORLP00000034899	E1A binding protein p300 b.	Uncharacterized protein.	0.622
LOC101168870	sp1	ENSORLP00000032567	ENSORLP00000034132	E1A binding protein p300 b.	Sp1 transcription factor.	0.945
NCOA3	LOC100049233	ENSORLP00000015195	ENSORLP00000011941	Nuclear receptor coactivator.	Androgen receptor beta subtype.	0.730
NCOA3	LOC101168870	ENSORLP00000015195	ENSORLP00000032567	Nuclear receptor coactivator.	E1A binding protein p300 b.	0.667
NCOA3	ar-alpha	ENSORLP00000015195	ENSORLP00000010323	Nuclear receptor coactivator.	Uncharacterized protein.	0.730