(33 nodes) Coagulation, and Protease inhibitor complex network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101154762	Coagulation factor VII, like. (429 aa)
	LOC101155013	Coagulation factor VII. (434 aa)
	serpind1	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family. (505 aa)
	fga	Fibrinogen alpha chain. (750 aa)
	fgb	Fibrinogen beta chain. (498 aa)
	LOC101174928	Coagulation factor VIII, procoagulant component; Belongs to the multicopper oxidase family. (1591 aa)
	wap65-like	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (433 aa)
	f3	Coagulation factor IIIa. (284 aa)
	proc	Protein C (inactivator of coagulation factors Va and VIIIa), a. (436 aa)
	LOC101164095	Uncharacterized protein. (286 aa)
	LOC101156578	Protein Z, vitamin K-dependent plasma glycoprotein a; Belongs to the peptidase S1 family. (416 aa)
	LOC101168652	Alpha-2-HS-glycoprotein 2. (397 aa)
	plau	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family. (388 aa)
	serpine3	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3; Belongs to the serpin family. (446 aa)
	serpine1	SERPIN domain-containing protein; Belongs to the serpin family. (447 aa)
	LOC101163240	Uncharacterized protein. (352 aa)
	APOH	Uncharacterized protein. (364 aa)
	APOH-2	Apolipoprotein H. (362 aa)
	plau-2	Urokinase type plasminogen activator. (453 aa)
	stil	SERPIN domain-containing protein; Belongs to the serpin family. (1406 aa)
	LOC101174546	Uncharacterized protein. (308 aa)
	serpina10	Si:ch1073-416d2.3; Belongs to the serpin family. (405 aa)
	olklklp	Kallikrein like protein; Belongs to the peptidase S1 family. (275 aa)
	LOC111948660	Coagulation factor IXb. (550 aa)
	plat	Uncharacterized protein. (607 aa)
	serpina10-2	Si:ch1073-416d2.3; Belongs to the serpin family. (404 aa)
	LOC101170246	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (617 aa)
	ENSORLP00000034547	Coagulation factor X. (498 aa)
	LOC101170257	Microseminoprotein, beta-like. (311 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (494 aa)
	ENSORLP00000043209	Alpha-1-microglobulin/bikunin precursor. (355 aa)
	ENSORLP00000044973	Uncharacterized protein. (361 aa)
	ENSORLP00000045882	SERPIN domain-containing protein; Belongs to the serpin family. (228 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOH	ENSORLP00000043209	ENSORLP00000017331	ENSORLP00000043209	Uncharacterized protein.	Alpha-1-microglobulin/bikunin precursor.	0.706
APOH	LOC101163240	ENSORLP00000017331	ENSORLP00000015534	Uncharacterized protein.	Uncharacterized protein.	0.648
APOH	LOC101168652	ENSORLP00000017331	ENSORLP00000011437	Uncharacterized protein.	Alpha-2-HS-glycoprotein 2.	0.789
APOH	LOC101170246	ENSORLP00000017331	ENSORLP00000033975	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.769
APOH	LOC101170257	ENSORLP00000017331	ENSORLP00000035771	Uncharacterized protein.	Microseminoprotein, beta-like.	0.528
APOH	fga	ENSORLP00000017331	ENSORLP00000003045	Uncharacterized protein.	Fibrinogen alpha chain.	0.696
APOH	fgb	ENSORLP00000017331	ENSORLP00000003101	Uncharacterized protein.	Fibrinogen beta chain.	0.585
APOH	proc	ENSORLP00000017331	ENSORLP00000008456	Uncharacterized protein.	Protein C (inactivator of coagulation factors Va and VIIIa), a.	0.542
APOH	serpind1	ENSORLP00000017331	ENSORLP00000002789	Uncharacterized protein.	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.	0.550
APOH	stil	ENSORLP00000017331	ENSORLP00000017607	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.713
APOH	wap65-like	ENSORLP00000017331	ENSORLP00000004739	Uncharacterized protein.	Hemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.	0.509
APOH-2	ENSORLP00000043209	ENSORLP00000017341	ENSORLP00000043209	Apolipoprotein H.	Alpha-1-microglobulin/bikunin precursor.	0.706
APOH-2	LOC101163240	ENSORLP00000017341	ENSORLP00000015534	Apolipoprotein H.	Uncharacterized protein.	0.648
APOH-2	LOC101168652	ENSORLP00000017341	ENSORLP00000011437	Apolipoprotein H.	Alpha-2-HS-glycoprotein 2.	0.789
APOH-2	LOC101170246	ENSORLP00000017341	ENSORLP00000033975	Apolipoprotein H.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.769
APOH-2	LOC101170257	ENSORLP00000017341	ENSORLP00000035771	Apolipoprotein H.	Microseminoprotein, beta-like.	0.528
APOH-2	fga	ENSORLP00000017341	ENSORLP00000003045	Apolipoprotein H.	Fibrinogen alpha chain.	0.696
APOH-2	fgb	ENSORLP00000017341	ENSORLP00000003101	Apolipoprotein H.	Fibrinogen beta chain.	0.585
APOH-2	proc	ENSORLP00000017341	ENSORLP00000008456	Apolipoprotein H.	Protein C (inactivator of coagulation factors Va and VIIIa), a.	0.542
APOH-2	serpind1	ENSORLP00000017341	ENSORLP00000002789	Apolipoprotein H.	Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.	0.550