(12 nodes) Protein-lipid complex remodeling, and Apolipoprotein A/E network (Oryzias latipes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	cetp	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (503 aa)
	H2MBB3_ORYLA	Vitellogenin domain-containing protein. (793 aa)
	LOC101158990	Apolipoprotein Bb, tandem duplicate 2. (2459 aa)
	LOC101161673	Apolipoprotein Eb. (265 aa)
	LOC101169721	Apolipoprotein A-Ib. (323 aa)
	mttp	Microsomal triglyceride transfer protein. (886 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (532 aa)
	LOC101162068	Uncharacterized protein. (83 aa)
	LOC101156458	Apolipoprotein Ba. (4366 aa)
	LOC101161189	Uncharacterized protein. (274 aa)
	LOC101161439	Uncharacterized protein. (272 aa)
	LOC101166399	Apolipoprotein Ea. (262 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H2MBB3_ORYLA	LOC101156458	ENSORLP00000015834	ENSORLP00000041747	Vitellogenin domain-containing protein.	Apolipoprotein Ba.	0.562
H2MBB3_ORYLA	LOC101158990	ENSORLP00000015834	ENSORLP00000015852	Vitellogenin domain-containing protein.	Apolipoprotein Bb, tandem duplicate 2.	0.555
H2MBB3_ORYLA	LOC101161189	ENSORLP00000015834	ENSORLP00000042776	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.850
H2MBB3_ORYLA	LOC101161439	ENSORLP00000015834	ENSORLP00000043682	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.850
H2MBB3_ORYLA	LOC101161673	ENSORLP00000015834	ENSORLP00000017533	Vitellogenin domain-containing protein.	Apolipoprotein Eb.	0.896
H2MBB3_ORYLA	LOC101162068	ENSORLP00000015834	ENSORLP00000028652	Vitellogenin domain-containing protein.	Uncharacterized protein.	0.745
H2MBB3_ORYLA	LOC101166399	ENSORLP00000015834	ENSORLP00000045105	Vitellogenin domain-containing protein.	Apolipoprotein Ea.	0.871
H2MBB3_ORYLA	LOC101169721	ENSORLP00000015834	ENSORLP00000019715	Vitellogenin domain-containing protein.	Apolipoprotein A-Ib.	0.925
H2MBB3_ORYLA	cetp	ENSORLP00000015834	ENSORLP00000000460	Vitellogenin domain-containing protein.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.860
H2MBB3_ORYLA	mttp	ENSORLP00000015834	ENSORLP00000024167	Vitellogenin domain-containing protein.	Microsomal triglyceride transfer protein.	0.899
H2MBB3_ORYLA	scarb1	ENSORLP00000015834	ENSORLP00000028225	Vitellogenin domain-containing protein.	Scavenger receptor class B, member 1; Belongs to the CD36 family.	0.748
LOC101156458	H2MBB3_ORYLA	ENSORLP00000041747	ENSORLP00000015834	Apolipoprotein Ba.	Vitellogenin domain-containing protein.	0.562
LOC101156458	LOC101158990	ENSORLP00000041747	ENSORLP00000015852	Apolipoprotein Ba.	Apolipoprotein Bb, tandem duplicate 2.	0.565
LOC101156458	LOC101161189	ENSORLP00000041747	ENSORLP00000042776	Apolipoprotein Ba.	Uncharacterized protein.	0.850
LOC101156458	LOC101161439	ENSORLP00000041747	ENSORLP00000043682	Apolipoprotein Ba.	Uncharacterized protein.	0.850
LOC101156458	LOC101161673	ENSORLP00000041747	ENSORLP00000017533	Apolipoprotein Ba.	Apolipoprotein Eb.	0.941
LOC101156458	LOC101162068	ENSORLP00000041747	ENSORLP00000028652	Apolipoprotein Ba.	Uncharacterized protein.	0.745
LOC101156458	LOC101166399	ENSORLP00000041747	ENSORLP00000045105	Apolipoprotein Ba.	Apolipoprotein Ea.	0.911
LOC101156458	LOC101169721	ENSORLP00000041747	ENSORLP00000019715	Apolipoprotein Ba.	Apolipoprotein A-Ib.	0.925
LOC101156458	cetp	ENSORLP00000041747	ENSORLP00000000460	Apolipoprotein Ba.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.892