(142 nodes) Mixed, incl. Rab regulation of trafficking, and Exocytosis network (Oryzias latipes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101172416	Uncharacterized protein. (467 aa)
	H2L484_ORYLA	C2 domain-containing protein. (240 aa)
	rab28	Uncharacterized protein. (221 aa)
	scamp3	Secretory carrier-associated membrane protein. (334 aa)
	LOC101155198	Si:dkey-16l2.16. (210 aa)
	LOC101175074	RIC3 domain-containing protein. (354 aa)
	LOC101165216	Secretory carrier-associated membrane protein. (336 aa)
	LOC101165244	Info solute carrier family 35 member F2, like. (401 aa)
	c9h22orf39	Si:ch211-51h9.6. (99 aa)
	ninl	Ninein-like. (1220 aa)
	znf652	Zinc finger protein 652. (676 aa)
	LOC101155661	Uncharacterized protein. (675 aa)
	LOC101171557	DAZ interacting zinc finger protein 1. (843 aa)
	LOC101174246	Tetraspanin. (245 aa)
	LOC101159320	DAN domain family, member 5. (295 aa)
	rab12	RAB12, member RAS oncogene family. (253 aa)
	LOC101163088	Solute carrier family 35 member D2. (335 aa)
	spout1	SPOUT domain containing methyltransferase 1. (345 aa)
	TMEM158	Transmembrane protein 158 (gene/pseudogene). (274 aa)
	baiap3	BAI1-associated protein 3. (1177 aa)
	chst10	Carbohydrate sulfotransferase. (388 aa)
	bicc1	BicC family RNA binding protein 1a. (963 aa)
	GOLM1	Golgi membrane protein 1. (406 aa)
	unc50	Unc-50 homolog (C. elegans). (257 aa)
	LOC101175439	Double C2-like domains, alpha. (441 aa)
	cracr2b	Calcium release activated channel regulator 2B. (419 aa)
	LOC101165578	Down syndrome cell adhesion molecule like 1. (2054 aa)
	tbc1d24	TBC1 domain family, member 24. (568 aa)
	sapcd2	Suppressor APC domain containing 2. (453 aa)
	LOC101155765	C2 calcium dependent domain containing 4A. (449 aa)
	LOC101157158	Thioredoxin domain-containing protein. (426 aa)
	LOC101171754	LON peptidase N-terminal domain and ring finger 1. (585 aa)
	LOC101162993	Uncharacterized protein. (425 aa)
	LOC101166249	Uncharacterized protein. (1274 aa)
	rab27a	RAB27A, member RAS oncogene family. (220 aa)
	dennd1b	DENN/MADD domain containing 1B. (868 aa)
	DSCAML1	DS cell adhesion molecule like 1. (2021 aa)
	sdk1	Sidekick cell adhesion molecule 1a. (2140 aa)
	LOC101157981	Uncharacterized protein. (1146 aa)
	hivep1	Human immunodeficiency virus type I enhancer binding protein 1. (2533 aa)
	TBC1D8	TBC1 domain family member 8. (984 aa)
	LOC101168383	Organic solute carrier partner 1a. (385 aa)
	fam189b	Si:dkey-7f3.9. (739 aa)
	LOC101170358	Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (1872 aa)
	wdr54	WD repeat domain 54. (336 aa)
	LOC101167502	EH-domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (546 aa)
	LOC101160701	UDENN domain-containing protein. (1018 aa)
	SCCPDH	Saccharopine dehydrogenase a, tandem duplicate 1. (427 aa)
	LOC101172793	Si:dkey-76b14.2. (794 aa)
	zbed4	Zinc finger, BED-type containing 4. (1251 aa)
	LOC101164850	Jagunal homolog 1a. (181 aa)
	H2M963_ORYLA	Uncharacterized protein. (343 aa)
	LOC101155317	Uncharacterized protein. (438 aa)
	LOC101160735	Uncharacterized protein. (229 aa)
	TMX3	Thioredoxin related transmembrane protein 3. (477 aa)
	LOC101158451	DiGeorge syndrome critical region gene 6. (193 aa)
	dennd1a	DENN/MADD domain containing 1A. (942 aa)
	ccdc90b	Coiled-coil domain containing 90B. (243 aa)
	LOC101166820	Uncharacterized protein. (440 aa)
	OSCP1	Organic solute carrier partner 1. (394 aa)
	slc35f2	Solute carrier family 35 member F2. (372 aa)
	gnb1l	Guanine nucleotide binding protein (G protein), beta polypeptide 1-like. (328 aa)
	LOC101163320	LIM zinc-binding domain-containing protein. (639 aa)
	pcnx4	Pecanex 4. (1204 aa)
	LOC101164063	Tetraspanin. (265 aa)
	LOC101164255	Si:ch211-106h4.9. (1145 aa)
	ebpl	EBP like. (213 aa)
	LOC101165120	Si:dkey-191g9.5. (556 aa)
	tbc1d25	TBC1 domain family, member 25. (841 aa)
	TBC1D13	TBC1 domain family member 13. (400 aa)
	GPR180	G protein-coupled receptor 180. (504 aa)
	dennd4b	DENN/MADD domain containing 4B. (1361 aa)
	ENSORLP00000025928	Uncharacterized protein. (166 aa)
	ZNF516	Zinc finger protein 516. (1055 aa)
	LOC101163330	RAB3D, member RAS oncogene family, b. (229 aa)
	elmod1	ELMO/CED-12 domain containing 1. (327 aa)
	tbc1d9	TBC1 domain family, member 9 (with GRAM domain). (1274 aa)
	LOC101172731	Uncharacterized protein. (1298 aa)
	dennd2b	Suppression of tumorigenicity 5. (1134 aa)
	madd	MAP-kinase activating death domain. (1677 aa)
	LOC101172056	H6 family homeobox 1. (303 aa)
	LOC101159427	Secretory carrier-associated membrane protein. (233 aa)
	JAGN1	Jagunal homolog 1. (183 aa)
	tbc1d10a	TBC1 domain family, member 10Ab. (474 aa)
	LOC101169362	Sidekick cell adhesion molecule 2a. (2155 aa)
	RAB26	RAB26, member RAS oncogene family. (253 aa)
	phpt1	Uncharacterized protein. (136 aa)
	dennd2d	DENN/MADD domain containing 2Da. (595 aa)
	LOC101158431	Secretory carrier-associated membrane protein. (195 aa)
	ENSORLP00000030876	LIM zinc-binding domain-containing protein. (1167 aa)
	LOC105356386	DBB domain-containing protein. (589 aa)
	dennd5a	DENN/MADD domain containing 5A. (1301 aa)
	LOC101160989	Zinc finger protein 516. (879 aa)
	LOC101171075	Secretory carrier-associated membrane protein. (230 aa)
	ENSORLP00000031623	Calponin-homology (CH) domain-containing protein. (132 aa)
	LOC105354860	Transmembrane protein 265. (354 aa)
	LOC101154860	Uncharacterized protein. (193 aa)
	dennd4a	DENN/MADD domain containing 4A. (1700 aa)
	elmod3	ELMO/CED-12 domain containing 3. (451 aa)
	unc13d	Unc-13 homolog D (C. elegans). (730 aa)
	LOC101156656	LIM domain and actin binding 1a. (736 aa)
	LOC101164523	Centrosomal protein 57, like 1. (508 aa)
	ENSORLP00000033489	FAD_binding_3 domain-containing protein. (323 aa)
	sh3bp2	SH3-domain binding protein 2. (609 aa)
	LOC101167390	Transmembrane protein 45B. (280 aa)
	mink1	Misshapen-like kinase 1. (1254 aa)
	c8h16orf89	Si:ch211-76l23.7. (383 aa)
	LOC110014564	LIM zinc-binding domain-containing protein. (378 aa)
	LOC101164901	Rab-GAP TBC domain-containing protein. (1092 aa)
	tbc1d10b	TBC1 domain family, member 10b. (871 aa)
	LOC101158204	TBC1 domain family, member 10Aa. (510 aa)
	LOC101167452	UDENN domain-containing protein. (1076 aa)
	LOC105355162	Uncharacterized protein. (1430 aa)
	acap2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (857 aa)
	rab27b	RAB27B, member RAS oncogene family. (218 aa)
	ENSORLP00000036347	C2 domain-containing protein. (108 aa)
	LOC101157825	Zinc finger protein 410. (421 aa)
	LOC101169380	Uncharacterized protein. (1231 aa)
	ENSORLP00000038089	Uncharacterized protein. (135 aa)
	ENSORLP00000039004	C2 domain-containing protein. (115 aa)
	ENSORLP00000039142	Uncharacterized protein. (277 aa)
	LOC101162341	Secretory carrier-associated membrane protein. (333 aa)
	LOC101171492	Microtubule associated monooxygenase, calponin and LIM domain containing 1. (1279 aa)
	sytl1	Synaptotagmin-like 1. (486 aa)
	lrrc66	IG domain-containing protein. (3004 aa)
	LOC101154838	Double C2-like domains, delta. (426 aa)
	phactr4	Phosphatase and actin regulator. (836 aa)
	LOC101163115	SH3-domain binding protein 1. (756 aa)
	LOC101158219	Trafficking regulator of GLUT4 (SLC2A4) 1b. (178 aa)
	ENSORLP00000041152	Uncharacterized protein. (75 aa)
	tbc1d9b	TBC1 domain family, member 9 (with GRAM domain). (1248 aa)
	doc2b	Double C2-like domain-containing protein. (394 aa)
	sytl4	Synaptotagmin-like 4. (733 aa)
	mical3	Microtubule associated monooxygenase, calponin and LIM domain containing 3a. (1967 aa)
	LOC101171164	Sushi domain-containing protein. (310 aa)
	DENND3	DENN domain containing 3. (1285 aa)
	tbc1d8b	TBC1 domain family member 8B. (1141 aa)
	sdk2	Sidekick cell adhesion molecule 2b. (2178 aa)
	RASSF10	Ras association domain family member 10. (433 aa)
	dipk1c	Divergent protein kinase domain 1C. (465 aa)
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	LOC101168282	Phosphatase and actin regulator. (585 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND3	rab12	ENSORLP00000043272	ENSORLP00000004873	DENN domain containing 3.	RAB12, member RAS oncogene family.	0.702
DENND3	rab28	ENSORLP00000043272	ENSORLP00000000746	DENN domain containing 3.	Uncharacterized protein.	0.520
DSCAML1	LOC101169362	ENSORLP00000011246	ENSORLP00000029001	DS cell adhesion molecule like 1.	Sidekick cell adhesion molecule 2a.	0.428
DSCAML1	sdk2	ENSORLP00000011246	ENSORLP00000044163	DS cell adhesion molecule like 1.	Sidekick cell adhesion molecule 2b.	0.431
ENSORLP00000031623	ENSORLP00000033489	ENSORLP00000031623	ENSORLP00000033489	Calponin-homology (CH) domain-containing protein.	FAD_binding_3 domain-containing protein.	0.404
ENSORLP00000033489	ENSORLP00000031623	ENSORLP00000033489	ENSORLP00000031623	FAD_binding_3 domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.404
ENSORLP00000039004	H2L484_ORYLA	ENSORLP00000039004	ENSORLP00000000569	C2 domain-containing protein.	C2 domain-containing protein.	0.900
ENSORLP00000039004	H2M963_ORYLA	ENSORLP00000039004	ENSORLP00000015043	C2 domain-containing protein.	Uncharacterized protein.	0.896
GOLM1	LOC101159320	ENSORLP00000006765	ENSORLP00000004599	Golgi membrane protein 1.	DAN domain family, member 5.	0.408
GOLM1	LOC101163330	ENSORLP00000006765	ENSORLP00000026379	Golgi membrane protein 1.	RAB3D, member RAS oncogene family, b.	0.687
GOLM1	LOC101164063	ENSORLP00000006765	ENSORLP00000020753	Golgi membrane protein 1.	Tetraspanin.	0.553
GOLM1	LOC101174246	ENSORLP00000006765	ENSORLP00000004590	Golgi membrane protein 1.	Tetraspanin.	0.553
H2L484_ORYLA	ENSORLP00000039004	ENSORLP00000000569	ENSORLP00000039004	C2 domain-containing protein.	C2 domain-containing protein.	0.900
H2L484_ORYLA	H2M963_ORYLA	ENSORLP00000000569	ENSORLP00000015043	C2 domain-containing protein.	Uncharacterized protein.	0.899
H2M963_ORYLA	ENSORLP00000039004	ENSORLP00000015043	ENSORLP00000039004	Uncharacterized protein.	C2 domain-containing protein.	0.896
H2M963_ORYLA	H2L484_ORYLA	ENSORLP00000015043	ENSORLP00000000569	Uncharacterized protein.	C2 domain-containing protein.	0.899
H2M963_ORYLA	LOC101154838	ENSORLP00000015043	ENSORLP00000039547	Uncharacterized protein.	Double C2-like domains, delta.	0.758
H2M963_ORYLA	LOC101175439	ENSORLP00000015043	ENSORLP00000007682	Uncharacterized protein.	Double C2-like domains, alpha.	0.729
H2M963_ORYLA	doc2b	ENSORLP00000015043	ENSORLP00000041807	Uncharacterized protein.	Double C2-like domain-containing protein.	0.803
JAGN1	gnb1l	ENSORLP00000028628	ENSORLP00000019094	Jagunal homolog 1.	Guanine nucleotide binding protein (G protein), beta polypeptide 1-like.	0.487