(11 nodes) Kynurenine metabolic process, and Tryptophan catabolic process network (Oryzias latipes)

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	kmo	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (505 aa)
	kyat1	Kynurenine aminotransferase 1. (446 aa)
	kynu	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (464 aa)
	asmtl	Acetylserotonin O-methyltransferase-like. (667 aa)
	afmid	Arylformamidase. (291 aa)
	LOC101173380	Kynurenine aminotransferase 3. (448 aa)
	aldh8a1	Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family. (490 aa)
	acmsd	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
	tdo2	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (468 aa)
	aadat	Aminoadipate aminotransferase. (431 aa)
	haao	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101173380	aadat	ENSORLP00000020441	ENSORLP00000027164	Kynurenine aminotransferase 3.	Aminoadipate aminotransferase.	0.942
LOC101173380	acmsd	ENSORLP00000020441	ENSORLP00000022701	Kynurenine aminotransferase 3.	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	0.408
LOC101173380	afmid	ENSORLP00000020441	ENSORLP00000015409	Kynurenine aminotransferase 3.	Arylformamidase.	0.938
LOC101173380	kmo	ENSORLP00000020441	ENSORLP00000000998	Kynurenine aminotransferase 3.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.964
LOC101173380	kyat1	ENSORLP00000020441	ENSORLP00000005000	Kynurenine aminotransferase 3.	Kynurenine aminotransferase 1.	0.902
LOC101173380	kynu	ENSORLP00000020441	ENSORLP00000006395	Kynurenine aminotransferase 3.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.969
LOC101173380	tdo2	ENSORLP00000020441	ENSORLP00000025285	Kynurenine aminotransferase 3.	Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.	0.675
aadat	LOC101173380	ENSORLP00000027164	ENSORLP00000020441	Aminoadipate aminotransferase.	Kynurenine aminotransferase 3.	0.942
aadat	afmid	ENSORLP00000027164	ENSORLP00000015409	Aminoadipate aminotransferase.	Arylformamidase.	0.938
aadat	aldh8a1	ENSORLP00000027164	ENSORLP00000020703	Aminoadipate aminotransferase.	Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.464
aadat	haao	ENSORLP00000027164	ENSORLP00000037020	Aminoadipate aminotransferase.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.	0.585
aadat	kmo	ENSORLP00000027164	ENSORLP00000000998	Aminoadipate aminotransferase.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.958
aadat	kyat1	ENSORLP00000027164	ENSORLP00000005000	Aminoadipate aminotransferase.	Kynurenine aminotransferase 1.	0.942
aadat	kynu	ENSORLP00000027164	ENSORLP00000006395	Aminoadipate aminotransferase.	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.	0.956
acmsd	LOC101173380	ENSORLP00000022701	ENSORLP00000020441	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	Kynurenine aminotransferase 3.	0.408
acmsd	afmid	ENSORLP00000022701	ENSORLP00000015409	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	Arylformamidase.	0.577
acmsd	aldh8a1	ENSORLP00000022701	ENSORLP00000020703	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family.	0.966
acmsd	haao	ENSORLP00000022701	ENSORLP00000037020	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family.	0.987
acmsd	kmo	ENSORLP00000022701	ENSORLP00000000998	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.	0.790
acmsd	kyat1	ENSORLP00000022701	ENSORLP00000005000	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily.	Kynurenine aminotransferase 1.	0.408