28 items (Oryzias latipes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	fgf10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	LOC101162725	Fibronectin leucine rich transmembrane protein 2. (658 aa)
	fgf20a	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
	FGF6-2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	frs2	Fibroblast growth factor receptor substrate 2b. (526 aa)
	LOC101160640	Neuroplastin b. (394 aa)
	LOC101174326	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
	fgf20b	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	ENSORLP00000027361	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	LOC111946374	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	LOC101162992	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
	LOC105354210	Si:ch73-330k17.3. (192 aa)
	fgf19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
	Fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
	LOC101174825	Fibroblast growth factor receptor substrate 3. (608 aa)
	fgf7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
	LOC101170837	Uncharacterized protein. (284 aa)
	LOC101161650	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	LOC101171210	Fibronectin leucine rich transmembrane protein 2. (653 aa)
	FGF6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (263 aa)
	flrt3	Fibronectin leucine rich transmembrane 3. (650 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
	fgf18	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000027361	Fgf1	ENSORLP00000027361	ENSORLP00000001852	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.473
ENSORLP00000027361	LOC101161650	ENSORLP00000027361	ENSORLP00000007561	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.476
ENSORLP00000027361	LOC101162725	ENSORLP00000027361	ENSORLP00000019881	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibronectin leucine rich transmembrane protein 2.	0.401
ENSORLP00000027361	LOC101171210	ENSORLP00000027361	ENSORLP00000013784	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibronectin leucine rich transmembrane protein 2.	0.401
ENSORLP00000027361	fgf18	ENSORLP00000027361	ENSORLP00000038417	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.531
ENSORLP00000027361	fgf19	ENSORLP00000027361	ENSORLP00000000352	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.628
ENSORLP00000027361	fgf23	ENSORLP00000027361	ENSORLP00000019815	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.600
ENSORLP00000027361	fgf3	ENSORLP00000027361	ENSORLP00000000370	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.562
ENSORLP00000027361	fgf4	ENSORLP00000027361	ENSORLP00000000362	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.573
ENSORLP00000027361	fgf7	ENSORLP00000027361	ENSORLP00000002929	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.464
ENSORLP00000027361	fgf8	ENSORLP00000027361	ENSORLP00000042553	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.543
ENSORLP00000027361	flrt3	ENSORLP00000027361	ENSORLP00000034138	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibronectin leucine rich transmembrane 3.	0.486
FGF6	fgf18	ENSORLP00000019694	ENSORLP00000038417	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.436
FGF6	fgf19	ENSORLP00000019694	ENSORLP00000000352	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.535
FGF6	fgf23	ENSORLP00000019694	ENSORLP00000019815	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.650
FGF6	fgf3	ENSORLP00000019694	ENSORLP00000000370	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.406
FGF6	flrt3	ENSORLP00000019694	ENSORLP00000034138	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibronectin leucine rich transmembrane 3.	0.418
FGF6-2	fgf18	ENSORLP00000044445	ENSORLP00000038417	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.474
FGF6-2	fgf19	ENSORLP00000044445	ENSORLP00000000352	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.542
FGF6-2	fgf23	ENSORLP00000044445	ENSORLP00000019815	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.650