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rpusd2 rpusd2 LOC101168403 LOC101168403 gnl3 gnl3 Rpl35 Rpl35 fcf1 fcf1 imp4 imp4 pih1d1 pih1d1 mettl5 mettl5 exosc4 exosc4 tfb1m tfb1m nol10 nol10 ddx51 ddx51 wdr43 wdr43 rpl7l1 rpl7l1 esf1 esf1 dkc1 dkc1 utp18 utp18 mrpl1 mrpl1 mak16 mak16 utp25 utp25 krr1 krr1 H2MZD9_ORYLA H2MZD9_ORYLA wdr36 wdr36 nol8 nol8 zcchc4 zcchc4 pop4 pop4 wdr74 wdr74 rpp30 rpp30 gar1 gar1 pelp1 pelp1 mrm2 mrm2 nvl nvl ddx52 ddx52 rpp40 rpp40 rpusd1 rpusd1 LOC111947823 LOC111947823 bms1 bms1 nhp2 nhp2 LOC101168761 LOC101168761 eri2 eri2 nob1 nob1 Esf1 Esf1 ENSORLP00000030839 ENSORLP00000030839 drosha drosha bud23 bud23 pes1 pes1 eri1 eri1 trmt61b trmt61b rrp36 rrp36 dhx37 dhx37 ercc2 ercc2 exosc3 exosc3 SART1 SART1 mettl15 mettl15 ENSORLP00000033383 ENSORLP00000033383 fam207a fam207a ENSORLP00000033990 ENSORLP00000033990 KRI1 KRI1 znhit3 znhit3 Heatr1 Heatr1 ENSORLP00000036101 ENSORLP00000036101 pa2g4 pa2g4 lsm6 lsm6 mrm3 mrm3 pih1d2 pih1d2 ENSORLP00000039518 ENSORLP00000039518 ENSORLP00000039784 ENSORLP00000039784 tbl3 tbl3 nol9 nol9 Wdr3 Wdr3 ybey ybey Mrm1 Mrm1 tsr2 tsr2 mrto4 mrto4 c1d c1d rexo4 rexo4 wdr12 wdr12 helq helq abt1 abt1 utp15 utp15 exosc9 exosc9 utp23 utp23 bop1 bop1 ddx56 ddx56 rbm34 rbm34 bysl bysl mphosph6 mphosph6 wdr18 wdr18 LOC101167684 LOC101167684 LOC101170587 LOC101170587 exosc2 exosc2 ddx54 ddx54 pin4 pin4 trmt2b trmt2b rpf1 rpf1 gtpbp4 gtpbp4 ngdn ngdn ftsj3 ftsj3 brix1 brix1 alg9 alg9 mphosph10 mphosph10 nop14 nop14 prkdc prkdc mtrex mtrex nsun3 nsun3 exosc10 exosc10 tsr1 tsr1 nat10 nat10 LOC101158557 LOC101158557 znhit2 znhit2 imp3 imp3 rrp8 rrp8 exosc8 exosc8 utp3 utp3 Pop7 Pop7 tefm tefm rrp15 rrp15 nsun5 nsun5 urb1 urb1 fbl fbl riok3 riok3 nsa2 nsa2 rrp9 rrp9 ddx10 ddx10 eif6 eif6 rsl1d1 rsl1d1 LOC101164300 LOC101164300 wdr55 wdr55 dcaf13 dcaf13 trmt112 trmt112 exosc7 exosc7 LOC101162339 LOC101162339 tsr3 tsr3 mettl16 mettl16 rpl7 rpl7 ddx18 ddx18 frg1 frg1 riok1 riok1 LYAR LYAR H2LWA8_ORYLA H2LWA8_ORYLA npm3 npm3 ddx49 ddx49 nsun4 nsun4 riok2 riok2 nop53 nop53 rrp12 rrp12 tex10 tex10 utp20 utp20 dimt1 dimt1 rpp38 rpp38 gemin4 gemin4 ddx21 ddx21 nol6 nol6 rcl1 rcl1 ebna1bp2 ebna1bp2 ZNHIT6 ZNHIT6 wdr46 wdr46 tfb2m tfb2m mrpl44 mrpl44 mff mff emg1 emg1 nop2 nop2 nop9 nop9 H2MCJ8_ORYLA H2MCJ8_ORYLA ddx27 ddx27 rps25 rps25 exosc6 exosc6 H2MDY1_ORYLA H2MDY1_ORYLA H2MDZ5_ORYLA H2MDZ5_ORYLA pwp1 pwp1 NOL11 NOL11 srfbp1 srfbp1 mrps11 mrps11 utp11 utp11 pop5 pop5 rrp7a rrp7a utp4 utp4 wbp11 wbp11 ddx47 ddx47 rpf2 rpf2 wdr75 wdr75 H2MKQ7_ORYLA H2MKQ7_ORYLA LOC101173463 LOC101173463
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpusd2RNA pseudouridine synthase domain containing 2. (541 aa)
LOC101168403Uncharacterized protein. (345 aa)
gnl3Guanine nucleotide binding protein-like 3 (nucleolar). (591 aa)
Rpl35Ribosomal protein L35. (122 aa)
fcf1FCF1 rRNA-processing protein. (207 aa)
imp4IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
pih1d1PIH1 domain containing 1. (283 aa)
mettl5Methyltransferase like 5. (198 aa)
exosc4Exosome component 4. (244 aa)
tfb1mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (411 aa)
nol10Nucleolar protein 10. (681 aa)
ddx51DEAD (Asp-Glu-Ala-Asp) box polypeptide 51; Belongs to the DEAD box helicase family. (622 aa)
wdr43WD repeat domain 43. (646 aa)
rpl7l1Ribosomal protein L7-like 1. (247 aa)
esf1ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae). (513 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (507 aa)
utp18WD_REPEATS_REGION domain-containing protein. (577 aa)
mrpl1Mitochondrial ribosomal protein L1. (330 aa)
mak16Protein MAK16 homolog; Belongs to the MAK16 family. (339 aa)
utp25UTP25 small subunit processor component. (750 aa)
krr1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (381 aa)
H2MZD9_ORYLAUncharacterized protein. (151 aa)
wdr36WD repeat domain 36. (887 aa)
nol8Nucleolar protein 8. (1078 aa)
zcchc4Zinc finger, CCHC domain containing 4. (507 aa)
pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (221 aa)
wdr74WD repeat domain 74. (378 aa)
rpp30Ribonuclease P/MRP 30 subunit. (289 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (283 aa)
pelp1Proline, glutamate and leucine rich protein 1. (1248 aa)
mrm2Mitochondrial rRNA methyltransferase 2. (232 aa)
nvlNuclear VCP like. (815 aa)
ddx52DEAD (Asp-Glu-Ala-Asp) box polypeptide 52. (677 aa)
rpp40Uncharacterized protein. (379 aa)
rpusd1RNA pseudouridine synthase domain containing 1. (304 aa)
LOC111947823Uncharacterized protein. (118 aa)
bms1BMS1 ribosome biogenesis factor. (1247 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (151 aa)
LOC101168761Uncharacterized protein. (1041 aa)
eri2ERI1 exoribonuclease family member 2. (713 aa)
nob1NIN1 (RPN12) binding protein 1 homolog. (498 aa)
Esf1Uncharacterized protein. (126 aa)
ENSORLP00000030839Uncharacterized protein. (207 aa)
droshaDrosha ribonuclease III. (1317 aa)
bud23BUD23 rRNA methyltransferase and ribosome maturation factor. (282 aa)
pes1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (597 aa)
eri1Exoribonuclease 1. (342 aa)
trmt61btRNA methyltransferase 61B. (481 aa)
rrp36Ribosomal RNA processing 36. (341 aa)
dhx37DEAH (Asp-Glu-Ala-His) box polypeptide 37. (1143 aa)
ercc2Excision repair cross-complementation group 2. (761 aa)
exosc3Exosome component 3. (250 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (763 aa)
mettl15Methyltransferase like 15. (552 aa)
ENSORLP00000033383Uncharacterized protein. (210 aa)
fam207aFamily with sequence similarity 207 member A. (254 aa)
ENSORLP00000033990NOP10 ribonucleoprotein homolog (yeast). (64 aa)
KRI1KRI1 homolog. (445 aa)
znhit3Zinc finger, HIT-type containing 3. (200 aa)
Heatr1Uncharacterized protein. (156 aa)
ENSORLP00000036101annotation not available (118 aa)
pa2g4Proliferation-associated 2G4, a. (391 aa)
lsm6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (80 aa)
mrm3Mitochondrial rRNA methyltransferase 3a. (444 aa)
pih1d2PIH1 domain containing 2. (321 aa)
ENSORLP00000039518Uncharacterized protein. (207 aa)
ENSORLP00000039784Uncharacterized protein. (275 aa)
tbl3Transducin (beta)-like 3. (929 aa)
nol9Nucleolar protein 9. (701 aa)
Wdr3Uncharacterized protein. (80 aa)
ybeyYbeY metalloendoribonuclease. (167 aa)
Mrm1Mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae). (303 aa)
tsr2TSR2 ribosome maturation factor. (173 aa)
mrto4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
c1dC1D nuclear receptor corepressor. (156 aa)
rexo4REX4 homolog, 3'-5' exonuclease. (441 aa)
wdr12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
helqHelicase, POLQ like. (985 aa)
abt1Activator of basal transcription 1. (409 aa)
utp15UTP15 small subunit processome component. (528 aa)
exosc9Exosome component 9. (427 aa)
utp23UTP23 small subunit processome component. (255 aa)
bop1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (745 aa)
ddx56DEAD (Asp-Glu-Ala-Asp) box helicase 56. (558 aa)
rbm34RNA binding motif protein 34. (421 aa)
byslBystin-like. (437 aa)
mphosph6M-phase phosphoprotein 6. (162 aa)
wdr18WD repeat domain 18. (433 aa)
LOC101167684PWP2 small subunit processome component. (909 aa)
LOC101170587Proliferation-associated 2G4, b. (392 aa)
exosc2Exosome component 2. (293 aa)
ddx54ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (852 aa)
pin4Peptidyl-prolyl cis-trans isomerase. (135 aa)
trmt2btRNA methyltransferase 2 homolog B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (482 aa)
rpf1Ribosome production factor 1 homolog. (357 aa)
gtpbp4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
ngdnNeuroguidin, EIF4E binding protein. (344 aa)
ftsj3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (857 aa)
brix1Brix domain containing 2. (339 aa)
alg9Ferredoxin-fold anticodon binding domain containing 1. (667 aa)
mphosph10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (673 aa)
nop14NOP14 nucleolar protein homolog (yeast). (867 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3962 aa)
mtrexUncharacterized protein. (1036 aa)
nsun3NOP2/Sun RNA methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (430 aa)
exosc10Exosome component 10. (891 aa)
tsr1TSR1 ribosome maturation factor. (834 aa)
nat10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1037 aa)
LOC101158557Miff domain-containing protein. (307 aa)
znhit2Zinc finger, HIT-type containing 2. (568 aa)
imp3IMP U3 small nucleolar ribonucleoprotein 3. (183 aa)
rrp8Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (569 aa)
exosc8Exosome component 8. (277 aa)
utp3UTP3 small subunit processome component. (468 aa)
Pop7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. (139 aa)
tefmUTP6 small subunit processome component. (929 aa)
rrp15Ribosomal RNA processing 15 homolog. (265 aa)
nsun5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (474 aa)
urb1URB1 ribosome biogenesis homolog. (2245 aa)
fblFibrillarin. (348 aa)
riok3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (506 aa)
nsa2NSA2 ribosome biogenesis homolog (S. cerevisiae). (260 aa)
rrp9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (481 aa)
ddx10RNA helicase. (834 aa)
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (246 aa)
rsl1d1Ribosomal L1 domain containing 1. (349 aa)
LOC101164300RNA pseudouridine synthase D4. (407 aa)
wdr55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis, including thymus development; Belongs to the WD repeat WDR55 family. (401 aa)
dcaf13Ddb1 and cul4 associated factor 13. (445 aa)
trmt112tRNA methyltransferase subunit 11-2. (123 aa)
exosc7Exosome component 7. (291 aa)
LOC101162339Uncharacterized protein. (550 aa)
tsr3Probable ribosome biogenesis protein tsr3; Probable pre-rRNA processing protein involved in ribosome biogenesis. (287 aa)
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (570 aa)
rpl7Ribosomal protein L7. (245 aa)
ddx18RNA helicase. (643 aa)
frg1FSHD region gene 1. (274 aa)
riok1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (541 aa)
LYARLy1 antibody reactive. (394 aa)
H2LWA8_ORYLAUtp12 domain-containing protein. (211 aa)
npm3Nucleophosmin/nucleoplasmin, 3. (159 aa)
ddx49DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; Belongs to the DEAD box helicase family. (469 aa)
nsun4NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (393 aa)
riok2RIO domain-containing protein. (516 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (450 aa)
rrp12Ribosomal RNA processing 12 homolog. (1288 aa)
tex10Testis expressed 10. (941 aa)
utp20UTP20 small subunit processome component. (2503 aa)
dimt1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (306 aa)
rpp38Ribonuclease P/MRP 38 subunit. (275 aa)
gemin4Gem (nuclear organelle) associated protein 4. (1112 aa)
ddx21DEAD (Asp-Glu-Ala-Asp) box helicase 21. (649 aa)
nol6Nucleolar protein 6. (1137 aa)
rcl1RNA terminal phosphate cyclase-like 1. (372 aa)
ebna1bp2EBNA1 binding protein 2. (345 aa)
ZNHIT6Zinc finger HIT-type containing 6. (375 aa)
wdr46WD repeat domain 46. (614 aa)
tfb2mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (558 aa)
mrpl44Mitochondrial ribosomal protein L44. (369 aa)
mffMitochondrial fission factor. (289 aa)
emg1EMG1 N1-specific pseudouridine methyltransferase. (245 aa)
nop2SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (758 aa)
nop9Uncharacterized protein. (666 aa)
H2MCJ8_ORYLAProgrammed cell death 11. (891 aa)
ddx27DEAD (Asp-Glu-Ala-Asp) box polypeptide 27; Belongs to the DEAD box helicase family. (769 aa)
rps2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (122 aa)
exosc6Exosome component 6. (272 aa)
H2MDY1_ORYLABP28CT domain-containing protein. (341 aa)
H2MDZ5_ORYLARibonuclease P and MRP subunit p25, b. (217 aa)
pwp1PWP1 homolog, endonuclein. (494 aa)
NOL11Nucleolar protein 11. (718 aa)
srfbp1BUD22 domain-containing protein. (544 aa)
mrps11Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (248 aa)
utp11U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (253 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (166 aa)
rrp7aRibosomal RNA processing 7 homolog A. (282 aa)
utp4UTP4 small subunit processome component. (685 aa)
wbp11WW domain binding protein 11. (696 aa)
ddx47DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; Belongs to the DEAD box helicase family. (488 aa)
rpf2Ribosome production factor 2 homolog. (308 aa)
wdr75WD repeat domain 75. (834 aa)
H2MKQ7_ORYLAKRI1 homolog. (400 aa)
LOC101173463Zona pellucida glycoprotein d. (404 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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