120 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fbxo7	F-box protein 7. (452 aa)
	LOC101166216	Cyclin-dependent kinase inhibitor 1A. (156 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
	zgpat	Zinc finger, CCCH-type with G patch domain. (514 aa)
	H2L6D0_ORYLA	Uncharacterized protein. (176 aa)
	socs5	Suppressor of cytokine signaling 5. (561 aa)
	spry4	Sprouty homolog 4 (Drosophila). (378 aa)
	ibtk	Inhibitor of Bruton agammaglobulinemia tyrosine kinase. (1329 aa)
	LOC101161671	Tyrosine-protein phosphatase non-receptor type. (413 aa)
	LOC101162621	Neurofibromin 2b (merlin). (604 aa)
	LOC101159349	Protein kinase, cAMP-dependent, regulatory, type II, alpha A. (391 aa)
	sh2b3	SH2B adaptor protein 3. (724 aa)
	LOC101171191	Uncharacterized protein. (344 aa)
	rtraf	RNA transcription, translation and transport factor. (241 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	prkar1a	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b. (380 aa)
	LOC101174747	Inhibitor_Mig-6 domain-containing protein. (374 aa)
	prkar2b	Protein kinase cAMP-dependent type II regulatory subunit beta. (409 aa)
	cep85	Centrosomal protein 85. (772 aa)
	LOC101171145	Sprouty RTK signaling antagonist 2. (342 aa)
	smpd1	Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (604 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (460 aa)
	LOC101157228	SH3-domain binding protein 5a (BTK-associated). (440 aa)
	cbl	Cbl proto-oncogene, E3 ubiquitin protein ligase. (946 aa)
	LOC101166150	Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (198 aa)
	sfrp2	Secreted frizzled-related protein 2. (290 aa)
	prkar1b	Protein kinase, cAMP-dependent, regulatory, type I, beta. (380 aa)
	adar	Adenosine deaminase RNA specific. (1336 aa)
	sorl1	Sortilin-related receptor, L(DLR class) A repeats containing. (2051 aa)
	gba	Glucosylceramidase. (522 aa)
	LOC101172093	General transcription factor IIH, polypeptide 4. (392 aa)
	qars1	Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (774 aa)
	LOC101171428	FZ domain-containing protein. (337 aa)
	SMYD3	SET and MYND domain containing 3. (437 aa)
	PAQR3	Progestin and adipoQ receptor family member IIIb. (315 aa)
	cdk5rap1	CDK5 regulatory subunit associated protein 1. (587 aa)
	men1	Multiple endocrine neoplasia I. (691 aa)
	TSC2	TSC complex subunit 2. (1608 aa)
	dusp10	Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (472 aa)
	bmp4	Bone morphogenetic protein 4. (441 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (680 aa)
	LOC101168659	Dual specificity phosphatase 19a. (207 aa)
	H2MFW2_ORYLA	Si:dkeyp-97e7.9. (398 aa)
	LOC101161673	Apolipoprotein Eb. (265 aa)
	ppm1e	Protein phosphatase, Mg2+/Mn2+ dependent, 1E. (616 aa)
	wars1	Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (493 aa)
	LOC101163758	Uncharacterized protein. (852 aa)
	ptpn1	Tyrosine-protein phosphatase non-receptor type. (432 aa)
	TFAP4	Transcription factor AP-4 (activating enhancer binding protein 4). (332 aa)
	H2MJT0_ORYLA	Uncharacterized protein. (589 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (198 aa)
	SPRY3	Sprouty RTK signaling antagonist 3. (273 aa)
	zfyve28	Zinc finger, FYVE domain containing 28. (935 aa)
	ppm1f	Protein phosphatase, Mg2+/Mn2+ dependent, 1F. (432 aa)
	LOC100125499	3-hydroxy-3-methylglutaryl coenzyme A reductase. (865 aa)
	lats1	Large tumor suppressor kinase 1. (1063 aa)
	paqr3	Progestin and adipoQ receptor family member IIIa. (310 aa)
	fgfr1op	FOP_dimer domain-containing protein. (405 aa)
	H2MW65_ORYLA	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B. (232 aa)
	LOC101169916	Uncharacterized protein. (1868 aa)
	Nf1	Uncharacterized protein. (506 aa)
	LOC101158780	Tyrosine-protein phosphatase non-receptor type. (405 aa)
	ENSORLP00000026362	Fibronectin type-III domain-containing protein. (88 aa)
	akt1s1	Uncharacterized protein. (438 aa)
	dbndd1	Si:ch1073-174d20.1. (155 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (858 aa)
	lrp5	Low density lipoprotein receptor-related protein 5. (1634 aa)
	cblb	Cbl proto-oncogene B, E3 ubiquitin protein ligase. (906 aa)
	ptpro	Protein tyrosine phosphatase receptor type O. (1225 aa)
	ENSORLP00000028232	Fibronectin type-III domain-containing protein. (94 aa)
	LOC101166028	Zgc:123278. (182 aa)
	fam72a	Family with sequence similarity 72 member B. (180 aa)
	tmem130	Transmembrane protein 130. (311 aa)
	LOC101160207	Uncharacterized protein. (317 aa)
	cdkn2b	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (227 aa)
	hexim1	HEXIM P-TEFb complex subunit 1. (363 aa)
	socs9	Suppressor of cytokine signaling 9. (544 aa)
	pkig	Protein kinase (cAMP-dependent, catalytic) inhibitor gamma. (77 aa)
	chp1	Calcineurin-like EF-hand protein 1. (217 aa)
	Tsc2	DUF3384 domain-containing protein. (164 aa)
	MYOCD	Myocardin. (884 aa)
	aida	Axin interactor, dorsalization associated. (305 aa)
	ENSORLP00000033603	Fibronectin type-III domain-containing protein. (94 aa)
	cdkn1b	Cyclin-dependent kinase inhibitor 1Bb. (180 aa)
	LOC101169592	Dual specificity phosphatase 19b. (208 aa)
	ENSORLP00000034087	Fibronectin type-III domain-containing protein. (94 aa)
	lats2	Large tumor suppressor kinase 2. (1156 aa)
	LOC101166327	Si:dkey-175m17.7. (881 aa)
	ptprc	Protein tyrosine phosphatase receptor type C. (1343 aa)
	cdkn2c	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (168 aa)
	dtnbp1	Dystrobrevin binding protein 1b. (259 aa)
	LOC101175650	Zgc:174906. (228 aa)
	rb1	Retinoblastoma 1. (916 aa)
	GADD45B	Growth arrest and DNA damage inducible beta. (163 aa)
	nf2	Neurofibromin 2a (merlin). (610 aa)
	cdkn1c	Uncharacterized protein. (210 aa)
	ENSORLP00000038328	annotation not available (94 aa)
	sh3bp5	SH3-domain binding protein 5b (BTK-associated). (467 aa)
	LOC101166888	3-hydroxy-3-methylglutaryl coenzyme A reductase. (853 aa)
	LOC101163346	Bone morphogenetic protein 16. (516 aa)
	GPRC5D	G protein-coupled receptor class C group 5 member D. (410 aa)
	lrp6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1623 aa)
	errfi1	ERBB receptor feedback inhibitor 1a. (422 aa)
	deptor	DEP domain containing MTOR-interacting protein. (405 aa)
	LOC101159043	SH3-binding domain protein 5-like, a. (435 aa)
	ENSORLP00000043060	Uncharacterized protein. (81 aa)
	ptprq	Protein tyrosine phosphatase receptor type Q. (2073 aa)
	ENSORLP00000043583	Uncharacterized protein. (295 aa)
	LOC101171987-2	Uncharacterized protein. (81 aa)
	PTPRB	Protein tyrosine phosphatase receptor type B. (2056 aa)
	LOC101158476	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (557 aa)
	ENSORLP00000045038	Uncharacterized protein. (178 aa)
	LOC101166399	Apolipoprotein Ea. (262 aa)
	LOC101175405	Transcription factor AP-4 (activating enhancer binding protein 4). (330 aa)
	ptprh	Protein tyrosine phosphatase receptor type H. (1105 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (500 aa)
	ENSORLP00000045591	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (130 aa)
	LOC110015162	Si:ch211-253b8.5. (206 aa)
	LOC101175565	Uncharacterized protein. (210 aa)
	tsg101	Tumor susceptibility 101a. (384 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000043060	pkig	ENSORLP00000043060	ENSORLP00000032382	Uncharacterized protein.	Protein kinase (cAMP-dependent, catalytic) inhibitor gamma.	0.664
ENSORLP00000045038	cdkn2b	ENSORLP00000045038	ENSORLP00000031160	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	0.508
ENSORLP00000045038	cdkn2c	ENSORLP00000045038	ENSORLP00000035582	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	0.480
ENSORLP00000045038	rb1	ENSORLP00000045038	ENSORLP00000036779	Uncharacterized protein.	Retinoblastoma 1.	0.612
ENSORLP00000045591	adar	ENSORLP00000045591	ENSORLP00000012489	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Adenosine deaminase RNA specific.	0.487
ENSORLP00000045591	cav3	ENSORLP00000045591	ENSORLP00000000896	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.555
ENSORLP00000045591	sfrp2	ENSORLP00000045591	ENSORLP00000010461	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Secreted frizzled-related protein 2.	0.498
H2L6D0_ORYLA	cdkn2b	ENSORLP00000001376	ENSORLP00000031160	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	0.485
H2L6D0_ORYLA	cdkn2c	ENSORLP00000001376	ENSORLP00000035582	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	0.459
H2L6D0_ORYLA	rb1	ENSORLP00000001376	ENSORLP00000036779	Uncharacterized protein.	Retinoblastoma 1.	0.612
H2MFW2_ORYLA	akt1s1	ENSORLP00000017489	ENSORLP00000026390	Si:dkeyp-97e7.9.	Uncharacterized protein.	0.558
H2MJT0_ORYLA	Nf1	ENSORLP00000018929	ENSORLP00000026133	Uncharacterized protein.	Uncharacterized protein.	0.943
H2MW65_ORYLA	LOC101159349	ENSORLP00000023083	ENSORLP00000003822	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	Protein kinase, cAMP-dependent, regulatory, type II, alpha A.	0.548
H2MW65_ORYLA	prkar1a	ENSORLP00000023083	ENSORLP00000004817	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	Protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) b.	0.556
H2MW65_ORYLA	prkar1b	ENSORLP00000023083	ENSORLP00000010584	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	Protein kinase, cAMP-dependent, regulatory, type I, beta.	0.556
H2MW65_ORYLA	prkar2b	ENSORLP00000023083	ENSORLP00000005487	Protein kinase, cAMP-dependent, regulatory, type II, alpha, B.	Protein kinase cAMP-dependent type II regulatory subunit beta.	0.564
LOC100125499	LOC101161673	ENSORLP00000021654	ENSORLP00000017533	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Apolipoprotein Eb.	0.457
LOC100125499	LOC101166888	ENSORLP00000021654	ENSORLP00000039405	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.902
LOC101158476	LOC101171145	ENSORLP00000044381	ENSORLP00000005779	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	Sprouty RTK signaling antagonist 2.	0.882
LOC101158476	SPRY3	ENSORLP00000044381	ENSORLP00000019283	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	Sprouty RTK signaling antagonist 3.	0.765