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fgf19 fgf19 fgf4 fgf4 fgf3 fgf3 LOC101157631 LOC101157631 INHBB INHBB Fgf1 Fgf1 FGF13 FGF13 LOC101165892 LOC101165892 LOC101166137 LOC101166137 LOC101158789 LOC101158789 vegfc vegfc inha inha IL12B IL12B LOC101155037 LOC101155037 fgf7 fgf7 fgf11 fgf11 LOC101165330 LOC101165330 amh amh INHBC INHBC LOC101161650 LOC101161650 fgf16 fgf16 LOC101164147 LOC101164147 bmp6 bmp6 LOC101162532 LOC101162532 bmp8a bmp8a gdf6 gdf6 gdnf gdnf LOC100144359 LOC100144359 pdgfa pdgfa LOC101157368 LOC101157368 bmp15 bmp15 LOC101167980 LOC101167980 nodal nodal LOC101155815 LOC101155815 bmp2 bmp2 bmp5 bmp5 gdf3 gdf3 LOC101171139 LOC101171139 angptl3 angptl3 LOC101168287 LOC101168287 LOC101173146 LOC101173146 rabep2 rabep2 gfer gfer bmp4 bmp4 LOC101165149 LOC101165149 LOC101160897 LOC101160897 mdk mdk cxcl12 cxcl12 rabep1 rabep1 bmp10 bmp10 FGF6 FGF6 H2MLW1_ORYLA H2MLW1_ORYLA fgf23 fgf23 LOC101173579 LOC101173579 lefty1 lefty1 tgfb3 tgfb3 NRTN NRTN ogn ogn PSPN PSPN gdf10 gdf10 LOC101163237 LOC101163237 fgf20b fgf20b LOC101156096 LOC101156096 pdgfb pdgfb LOC101166903 LOC101166903 igf1 igf1 bmp3 bmp3 ENSORLP00000027361 ENSORLP00000027361 LOC101166036 LOC101166036 ENSORLP00000028183 ENSORLP00000028183 Kitlg Kitlg manf manf gdf11 gdf11 HDGFL3 HDGFL3 mia mia LOC111946374 LOC111946374 mstn mstn LOC101159516 LOC101159516 LOC101174977 LOC101174977 vegfa vegfa LOC101162992 LOC101162992 bdnf bdnf ENSORLP00000032081 ENSORLP00000032081 gmfb gmfb LOC101170230 LOC101170230 LOC101161449 LOC101161449 LOC105355769 LOC105355769 egf egf LOC101160461 LOC101160461 pdgfc pdgfc prok2 prok2 ntf3 ntf3 ENSORLP00000036734 ENSORLP00000036734 LOC101166855 LOC101166855 hdgf hdgf nenf nenf LOC101155207 LOC101155207 vegfb vegfb fgf5 fgf5 LOC101164582 LOC101164582 fgf18 fgf18 LOC101164584 LOC101164584 gdf5 gdf5 LOC101171064 LOC101171064 igf2 igf2 CCN3 CCN3 LOC101163346 LOC101163346 clec11a clec11a fgf10 fgf10 LOC101157715 LOC101157715 LOC101164758 LOC101164758 gsdf gsdf a-sdf1a a-sdf1a fgf8 fgf8 fgf20a fgf20a LOC101166143 LOC101166143 prok1 prok1 LOC101163116 LOC101163116 FGF14 FGF14 pdgfd pdgfd il34 il34 FGF6-2 FGF6-2 LOC101162318 LOC101162318 LOC101174326 LOC101174326 ptn ptn ENSORLP00000045700 ENSORLP00000045700 LOC101170375 LOC101170375
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
fgf3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
INHBBInhibin subunit beta B. (386 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
LOC101165892EGF-like domain-containing protein. (162 aa)
LOC101166137EGF-like domain-containing protein. (154 aa)
LOC101158789Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
vegfcPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (494 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (352 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (320 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
fgf7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa)
fgf11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
LOC101165330Glia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (142 aa)
amhAnti-muellerian hormone. (496 aa)
INHBCInhibin beta B chain-like protein. (379 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
LOC101164147Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (198 aa)
bmp6Bone morphogenetic protein 6. (424 aa)
LOC101162532Southpaw. (413 aa)
bmp8aBone morphogenetic protein 8a. (454 aa)
gdf6Growth differentiation factor 6b. (409 aa)
gdnfGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (265 aa)
LOC100144359TGF_BETA_2 domain-containing protein. (398 aa)
pdgfaPlatelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (227 aa)
LOC101157368Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (291 aa)
bmp15Bone morphogenetic protein 15. (444 aa)
LOC101167980TGF_BETA_2 domain-containing protein. (506 aa)
nodalNodal-related 2. (381 aa)
LOC101155815Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
bmp2TGF_BETA_2 domain-containing protein. (413 aa)
bmp5Bone morphogenetic protein 5. (417 aa)
gdf3Growth differentiation factor 3. (376 aa)
LOC101171139Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
angptl3Angiopoietin-like 3. (472 aa)
LOC101168287Colony stimulating factor 1b (macrophage). (301 aa)
LOC101173146Bone morphogenetic protein 7b. (427 aa)
rabep2Rabaptin, RAB GTPase binding effector protein 2. (458 aa)
gferSulfhydryl oxidase. (175 aa)
bmp4Bone morphogenetic protein 4. (441 aa)
LOC101165149Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (510 aa)
LOC101160897Bone morphogenetic protein 7a. (425 aa)
mdkMidkine b. (143 aa)
cxcl12Chemokine (C-X-C motif) ligand 12b; Belongs to the intercrine alpha (chemokine CxC) family. (102 aa)
rabep1Rabaptin, RAB GTPase binding effector protein 1. (858 aa)
bmp10Bone morphogenetic protein 10. (488 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (198 aa)
H2MLW1_ORYLAUncharacterized protein. (125 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (263 aa)
LOC101173579Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
lefty1Left-right determination factor. (358 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
NRTNNeurturin. (212 aa)
ognOsteoglycin, paralog a. (257 aa)
PSPNPersephin. (112 aa)
gdf10Growth differentiation factor 10b. (426 aa)
LOC101163237Growth differentiation factor 2. (415 aa)
fgf20bFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC101156096Heparin-binding EGF-like growth factor a. (233 aa)
pdgfbPlatelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (553 aa)
LOC101166903Interleukin 11a. (200 aa)
igf1Insulin-like growth factor 1. (199 aa)
bmp3Bone morphogenetic protein 3. (473 aa)
ENSORLP00000027361Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
LOC101166036Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (402 aa)
ENSORLP00000028183Uncharacterized protein. (250 aa)
KitlgKit ligand a. (233 aa)
manfMesencephalic astrocyte-derived neurotrophic factor. (180 aa)
gdf11Growth differentiation factor 11. (389 aa)
HDGFL3HDGF like 3. (211 aa)
miaMIA SH3 domain containing. (141 aa)
LOC111946374Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
mstnTGF_BETA_2 domain-containing protein. (424 aa)
LOC101159516Neuregulin 2b. (712 aa)
LOC101174977Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
LOC101162992Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (281 aa)
ENSORLP00000032081SCY domain-containing protein. (103 aa)
gmfbGlia maturation factor, beta. (199 aa)
LOC101170230Inhibin subunit beta Aa. (457 aa)
LOC101161449PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (135 aa)
LOC105355769EGF-like domain-containing protein. (520 aa)
egfEpidermal growth factor. (966 aa)
LOC101160461EGF-like domain-containing protein. (607 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (342 aa)
prok2Prokineticin 2. (131 aa)
ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (284 aa)
ENSORLP00000036734SCY domain-containing protein. (109 aa)
LOC101166855Transforming growth factor, alpha. (254 aa)
hdgfHeparin binding growth factor. (228 aa)
nenfNeudesin neurotrophic factor; Belongs to the cytochrome b5 family. (159 aa)
LOC101155207Betacellulin, epidermal growth factor family member. (183 aa)
vegfbPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (237 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
LOC101164582Neuregulin 2a. (711 aa)
fgf18Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC101164584Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
gdf5Growth differentiation factor 5. (567 aa)
LOC101171064Growth differentiation factor 6a. (437 aa)
igf2Insulin-like growth factor 2b. (212 aa)
CCN3Cellular communication network factor 3. (366 aa)
LOC101163346Bone morphogenetic protein 16. (516 aa)
clec11aC-type lectin domain containing 11A. (271 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
LOC101157715Bone morphogenetic protein 10, like. (441 aa)
LOC101164758Fibrosin. (1269 aa)
gsdfGonadal soma derived factor. (216 aa)
a-sdf1aChemokine (C-X-C motif) ligand 12a; Belongs to the intercrine alpha (chemokine CxC) family. (98 aa)
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
fgf20aFibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
LOC101166143Growth differentiation factor 9. (435 aa)
prok1Prokineticin 1. (106 aa)
LOC101163116Neuregulin 3b. (763 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (270 aa)
pdgfdPlatelet derived growth factor d. (404 aa)
il34Interleukin 34. (236 aa)
FGF6-2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
LOC101162318TGF_BETA_2 domain-containing protein. (298 aa)
LOC101174326Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (233 aa)
ptnPleiotrophin. (165 aa)
ENSORLP00000045700TGF_BETA_2 domain-containing protein. (131 aa)
LOC101170375Anti-dorsalizing morphogenic protein. (437 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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